Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal I Fares, J Chagraoui, Y Gareau, S Gingras, R Ruel, N Mayotte, E Csaszar, ... Science 345 (6203), 1509-1512, 2014 | 629 | 2014 |
EPCR expression marks UM171-expanded CD34+ cord blood stem cells I Fares, J Chagraoui, B Lehnertz, T MacRae, N Mayotte, E Tomellini, ... Blood, The Journal of the American Society of Hematology 129 (25), 3344-3351, 2017 | 191 | 2017 |
Identification of small molecules that support human leukemia stem cell activity ex vivo C Pabst, J Krosl, I Fares, G Boucher, R Ruel, A Marinier, S Lemieux, ... Nature methods 11 (4), 436-442, 2014 | 158 | 2014 |
Mapping human haematopoietic stem cells from haemogenic endothelium to birth V Calvanese, S Capellera-Garcia, F Ma, I Fares, S Liebscher, ES Ng, ... Nature 604 (7906), 534-540, 2022 | 113 | 2022 |
Integrin-α3 is a functional marker of ex vivo expanded human long-term hematopoietic stem cells E Tomellini, I Fares, B Lehnertz, J Chagraoui, N Mayotte, T MacRae, ... Cell reports 28 (4), 1063-1073. e5, 2019 | 58 | 2019 |
UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal J Chagraoui, B Lehnertz, S Girard, JF Spinella, I Fares, E Tomellini, ... PLoS One 14 (11), e0224900, 2019 | 53 | 2019 |
Self-calibrating supplemental oxygen delivery system PL Bliss, WS Davidson US Patent 6,910,482, 2005 | 52 | 2005 |
High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells B Gerby, DFT Veiga, J Krosl, S Nourreddine, J Ouellette, A Haman, ... The Journal of Clinical Investigation 126 (12), 4569-4584, 2016 | 39 | 2016 |
UM171 enhances lentiviral gene transfer and recovery of primitive human hematopoietic cells M Ngom, S Imren, T Maetzig, JE Adair, DJHF Knapp, J Chagraoui, I Fares, ... Molecular Therapy-Methods & Clinical Development 10, 156-164, 2018 | 32 | 2018 |
Small molecule regulation of normal and leukemic stem cells I Fares, L Rivest-Khan, S Cohen, G Sauvageau Current Opinion in Hematology 22 (4), 309-316, 2015 | 32 | 2015 |
Pyrimido [4, 5-B] indole derivatives and use thereof in the expansion of hematopoietic stem cells G Sauvageau, Y Gareau, R Ruel, S Gingras, I Fares US Patent 9,409,906, 2016 | 25 | 2016 |
BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes EJ Schaefer, HC Wang, HQ Karp, CA Meyer, P Cejas, MD Gearhart, ... Blood cancer discovery 3 (2), 116-135, 2022 | 21 | 2022 |
Decoding human hematopoietic stem cell self-renewal I Fares, V Calvanese, HKA Mikkola Current Stem Cell Reports 8 (2), 93-106, 2022 | 10 | 2022 |
UM171 is a novel and potent agonist Of human hematopoietic stem cell renewal I Fares, J Chagraoui, Y Gareau, S Gingras, R Rjean, E Csaszar, S Cohen, ... Blood 122 (21), 798, 2013 | 4 | 2013 |
Coordination of Pro-and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion J Chagraoui, E Tomellini, L Aubert, I Fares, JF Spinella, S Girard, ... Blood 132, 2555, 2018 | 2 | 2018 |
Dual effects of BCOR-PRC1. 1 dependent gene regulation mediate cooperation of BCOR and TET2 mutations in myeloid transformation EJ Schaefer, I Fares, C Meyer, P Cejas, A Apffel, M Schenone, HW Long, ... Blood 132, 651, 2018 | 2 | 2018 |
Screen for Small Molecules Capable of Expanding Human Hematopoietic Stem Cell Ex Vivo IH Fares, J Chagraoui, J Krosl, DC Roy, S Cohen, G Sauvageau Blood 118 (21), 1919, 2011 | 1 | 2011 |
MYCT1 controls environmental sensing in human haematopoietic stem cells J Aguadé-Gorgorió, Y Jami-Alahmadi, V Calvanese, M Kardouh, I Fares, ... Nature, 1-9, 2024 | | 2024 |
MYCT1 Controls Environmental Sensing to Maintain Self-Renewal in Human Hematopoietic Stem Cells J Aguade-Gorgorio, Y Jami-alahmadi, V Calvanese, M Kardouh, I Fares, ... Blood 142, 4042, 2023 | | 2023 |
Selection of human hematopoetic stem cells using EPCR G Sauvageau, I Fares, J Chagraoui US Patent 11,725,187, 2023 | | 2023 |