SARS-CoV-2 infection depends on cellular heparan sulfate and ACE2 TM Clausen, DR Sandoval, CB Spliid, J Pihl, HR Perrett, CD Painter, ... Cell 183 (4), 1043-1057. e15, 2020 | 1053 | 2020 |
Targeting human cancer by a glycosaminoglycan binding malaria protein A Salanti, TM Clausen, MØ Agerbæk, N Al Nakouzi, M Dahlbäck, HZ Oo, ... Cancer cell 28 (4), 500-514, 2015 | 230 | 2015 |
Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria TM Clausen, S Christoffersen, M Dahlbäck, AE Langkilde, KE Jensen, ... Journal of Biological Chemistry 287 (28), 23332-23345, 2012 | 212 | 2012 |
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 S Yuan, X Yin, X Meng, JFW Chan, ZW Ye, L Riva, L Pache, CCY Chan, ... Nature 593 (7859), 418-423, 2021 | 187 | 2021 |
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner MØ Agerbæk, SR Bang-Christensen, MH Yang, TM Clausen, MA Pereira, ... Nature communications 9 (1), 3279, 2018 | 132 | 2018 |
The GAGOme: a cell-based library of displayed glycosaminoglycans YH Chen, Y Narimatsu, TM Clausen, C Gomes, R Karlsson, C Steentoft, ... Nature Methods 15 (11), 881-888, 2018 | 124 | 2018 |
The chondroitin sulfate A-binding site of the VAR2CSA protein involves multiple N-terminal domains M Dahlbäck, LM Jørgensen, MA Nielsen, TM Clausen, SB Ditlev, ... Journal of Biological Chemistry 286 (18), 15908-15917, 2011 | 110 | 2011 |
Virus-like particle display of HER2 induces potent anti-cancer responses A Palladini, S Thrane, CM Janitzek, J Pihl, SB Clemmensen, ... Oncoimmunology 7 (3), e1408749, 2018 | 106 | 2018 |
A High-Throughput O-Glycopeptide Discovery Platform for Seromic Profiling O Blixt, E Cló, AS Nudelman, KK Sørensen, T Clausen, HH Wandall, ... Journal of proteome research 9 (10), 5250-5261, 2010 | 100 | 2010 |
Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1 M Ayres Pereira, T Mandel Clausen, C Pehrson, Y Mao, M Resende, ... PLoS pathogens 12 (8), e1005831, 2016 | 98 | 2016 |
The role of proteoglycans in cancer metastasis and circulating tumor cell analysis TD Ahrens, SR Bang-Christensen, AM Jørgensen, C Løppke, CB Spliid, ... Frontiers in cell and developmental biology 8, 749, 2020 | 72 | 2020 |
Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility TM Clausen, MA Pereira, N Al Nakouzi, HZ Oo, MØ Agerbæk, S Lee, ... Molecular Cancer Research 14 (12), 1288-1299, 2016 | 67 | 2016 |
Capture and detection of circulating glioma cells using the recombinant VAR2CSA malaria protein SR Bang-Christensen, RS Pedersen, MA Pereira, TM Clausen, C Løppke, ... Cells 8 (9), 998, 2019 | 62 | 2019 |
Spike-heparan sulfate interactions in SARS-CoV-2 infection FL Kearns, DR Sandoval, L Casalino, TM Clausen, MA Rosenfeld, ... Current opinion in structural biology 76, 102439, 2022 | 50 | 2022 |
An oncofetal glycosaminoglycan modification provides therapeutic access to cisplatin-resistant bladder cancer R Seiler, HZ Oo, D Tortora, TM Clausen, CK Wang, G Kumar, MA Pereira, ... European urology 72 (1), 142-150, 2017 | 49 | 2017 |
SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling SB Biering, FT Gomes de Sousa, LV Tjang, F Pahmeier, C Zhu, R Ruan, ... Nature Communications 13 (1), 7630, 2022 | 38 | 2022 |
Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity C Martino, BP Kellman, DR Sandoval, TM Clausen, CA Marotz, SJ Song, ... BioRxiv, 2020.08. 17.238444, 2020 | 35 | 2020 |
Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates R Karlsson, P Chopra, A Joshi, Z Yang, SY Vakhrushev, TM Clausen, ... Science advances 7 (52), eabl6026, 2021 | 32 | 2021 |
Noninvasive detection of any-stage cancer using free glycosaminoglycans S Bratulic, A Limeta, S Dabestani, H Birgisson, G Enblad, K Stålberg, ... Proceedings of the National Academy of Sciences 119 (50), e2115328119, 2022 | 31 | 2022 |
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding K Wang, R Dagil, T Lavstsen, SK Misra, CB Spliid, Y Wang, T Gustavsson, ... Nature Communications 12 (1), 2956, 2021 | 29 | 2021 |