Multi-scale approaches for the simulation of cardiac electrophysiology: I–Sub-cellular and stochastic calcium dynamics from cell to organ MA Colman, M Holmes, DG Whittaker, I Jayasinghe, AP Benson Methods 185, 49-59, 2021 | 13 | 2021 |
Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics M Holmes, ME Hurley, TMD Sheard, AP Benson, I Jayasinghe, ... Philosophical Transactions of the Royal Society B 377 (1864), 20210317, 2022 | 7 | 2022 |
Sub-cellular Heterogeneity in SERCA Determines Spatial Calcium Dynamics in Cardiomyocytes M Holmes, ME Hurley, TMD Sheard, HJ Stevenson-Cocks, A Benson, ... Biophysical Journal 118 (3), 172a-173a, 2020 | 1 | 2020 |
Investigating calcium-mediated arrhythmias via a computational model of a rabbit atrial myocyte M Holmes, AP Benson, OV Aslanidi, MA Colman 2018 Computing in Cardiology Conference (CinC) 45, 1-4, 2018 | 1 | 2018 |
Cardiac Digital Twin Pipeline for Virtual Therapy Evaluation J Camps, ZJ Wang, R Doste, M Holmes, B Lawson, J Tomek, K Burrage, ... arXiv preprint arXiv:2401.10029, 2024 | | 2024 |
The Influence of Calcium Handling Variability on Cardiac Electrophysiology in Ventricular and Atrial Myocytes M Holmes University of Leeds, 2021 | | 2021 |
Sensitivity of ECG and ejection fraction to human electromechanical myocardial properties in post-myocardial infarction ZJ Wang, M Holmes, R Doste, J Camps, X Zhou, B Rodriguez | | |
Online Supplement: Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics M Holmes, ME Hurley, TMD Sheard, AP Benson, I Jayasinghe, ... | | |
A Novel Model of the Rabbit Atrial Myocyte for the Study of Ca2+ Mediated Arrhythmia M Holmes, AP Benson, OV Aslanidi, MA Colman | | |