Identification of gastric cancer stem cells using the cell surface marker CD44 S Takaishi, T Okumura, S Tu, SSW Wang, W Shibata, R Vigneshwaran, ... Stem cells 27 (5), 1006-1020, 2009 | 1336 | 2009 |
Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth M Quante, SP Tu, H Tomita, T Gonda, SSW Wang, S Takashi, GH Baik, ... Cancer cell 19 (2), 257-272, 2011 | 1161 | 2011 |
Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling K Imajo, K Fujita, M Yoneda, Y Nozaki, Y Ogawa, Y Shinohara, S Kato, ... Cell metabolism 16 (1), 44-54, 2012 | 373 | 2012 |
Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth K Sakamoto, S Maeda, Y Hikiba, H Nakagawa, Y Hayakawa, W Shibata, ... Clinical Cancer Research 15 (7), 2248-2258, 2009 | 303 | 2009 |
Mist1 expressing gastric stem cells maintain the normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche Y Hayakawa, H Ariyama, J Stancikova, K Sakitani, S Asfaha, BW Renz, ... Cancer cell 28 (6), 800-814, 2015 | 295 | 2015 |
Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation H Nakagawa, S Maeda, Y Hikiba, T Ohmae, W Shibata, A Yanai, ... Gastroenterology 135 (4), 1311-1321, 2008 | 279 | 2008 |
Mice that express human interleukin-8 have increased mobilization of immature myeloid cells, which exacerbates inflammation and accelerates colon carcinogenesis S Asfaha, AN Dubeykovskiy, H Tomita, X Yang, S Stokes, W Shibata, ... Gastroenterology 144 (1), 155-166, 2013 | 200 | 2013 |
Cutting edge: the IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis W Shibata, S Maeda, Y Hikiba, A Yanai, T Ohmae, K Sakamoto, ... The Journal of Immunology 179 (5), 2681-2685, 2007 | 165 | 2007 |
Essential roles of high-mobility group box 1 in the development of murine colitis and colitis-associated cancer S Maeda, Y Hikiba, W Shibata, T Ohmae, A Yanai, K Ogura, S Yamada, ... Biochemical and biophysical research communications 360 (2), 394-400, 2007 | 155 | 2007 |
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis H Nakagawa, Y Hikiba, Y Hirata, J Font-Burgada, K Sakamoto, ... Proceedings of the National Academy of Sciences 111 (3), 1090-1095, 2014 | 133 | 2014 |
IFN-γ inhibits gastric carcinogenesis by inducing epithelial cell autophagy and T-cell apoptosis SP Tu, M Quante, G Bhagat, S Takaishi, G Cui, XD Yang, S Muthuplani, ... Cancer research 71 (12), 4247-4259, 2011 | 132 | 2011 |
Inhibition of gastric carcinogenesis by the hormone gastrin is mediated by suppression of TFF1 epigenetic silencing H Tomita, S Takaishi, TR Menheniott, X Yang, W Shibata, G Jin, KS Betz, ... Gastroenterology 140 (3), 879-891. e18, 2011 | 131 | 2011 |
The effect of Helicobacter pylori eradication on reducing the incidence of gastric cancer K Ogura, Y Hirata, A Yanai, W Shibata, T Ohmae, Y Mitsuno, S Maeda, ... Journal of clinical gastroenterology 42 (3), 279-283, 2008 | 120 | 2008 |
c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice W Shibata, S Maeda, Y Hikiba, A Yanai, K Sakamoto, H Nakagawa, ... Cancer research 68 (13), 5031-5039, 2008 | 113 | 2008 |
Interleukin-6 mediates epithelial–stromal interactions and promotes gastric tumorigenesis H Kinoshita, Y Hirata, H Nakagawa, K Sakamoto, Y Hayakawa, ... PloS one 8 (4), e60914, 2013 | 96 | 2013 |
MyD88 and TNF receptor-associated factor 6 are critical signal transducers in Helicobacter pylori-infected human epithelial cells Y Hirata, T Ohmae, W Shibata, S Maeda, K Ogura, H Yoshida, T Kawabe, ... The Journal of Immunology 176 (6), 3796-3803, 2006 | 96 | 2006 |
K-ras mutation targeted to gastric tissue progenitor cells results in chronic inflammation, an altered microenvironment, and progression to intraepithelial neoplasia T Okumura, RE Ericksen, S Takaishi, SSW Wang, Z Dubeykovskiy, ... Cancer research 70 (21), 8435-8445, 2010 | 92 | 2010 |
Folic acid increases global DNA methylation and reduces inflammation to prevent Helicobacter-associated gastric cancer in mice TA Gonda, YI Kim, MC Salas, MV Gamble, W Shibata, S Muthupalani, ... Gastroenterology 142 (4), 824-833. e7, 2012 | 86 | 2012 |
Stromal cell-derived factor-1 overexpression induces gastric dysplasia through expansion of stromal myofibroblasts and epithelial progenitors W Shibata, H Ariyama, CB Westphalen, DL Worthley, S Muthupalani, ... Gut 62 (2), 192-200, 2013 | 82 | 2013 |
Conditional deletion of IκB-kinase-β accelerates Helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia W Shibata, S Takaishi, S Muthupalani, DM Pritchard, MT Whary, ... Gastroenterology 138 (3), 1022-1034. e10, 2010 | 82 | 2010 |