The extracellular matrix modulates the hallmarks of cancer MW Pickup, JK Mouw, VM Weaver EMBO reports 15 (12), 1243-1253, 2014 | 1826 | 2014 |
The roles of TGFβ in the tumour microenvironment M Pickup, S Novitskiy, HL Moses Nature Reviews Cancer 13 (11), 788-799, 2013 | 999 | 2013 |
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression H Laklai, YA Miroshnikova, MW Pickup, EA Collisson, GE Kim, AS Barrett, ... Nature medicine 22 (5), 497-505, 2016 | 564 | 2016 |
Gr-1+ CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung HH Yan, M Pickup, Y Pang, AE Gorska, Z Li, A Chytil, Y Geng, JW Gray, ... Cancer research 70 (15), 6139-6149, 2010 | 416 | 2010 |
Tissue mechanics promote IDH1-dependent HIF1α–tenascin C feedback to regulate glioblastoma aggression YA Miroshnikova, JK Mouw, JM Barnes, MW Pickup, JN Lakins, Y Kim, ... Nature cell biology 18 (12), 1336-1345, 2016 | 326 | 2016 |
Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β–deficient mouse mammary carcinomas MW Pickup, H Laklai, I Acerbi, P Owens, AE Gorska, A Chytil, M Aakre, ... Cancer research 73 (17), 5336-5346, 2013 | 208 | 2013 |
From transformation to metastasis: deconstructing the extracellular matrix in breast cancer S Kaushik, MW Pickup, VM Weaver Cancer and Metastasis Reviews 35, 655-667, 2016 | 167 | 2016 |
TGF-β receptor II loss promotes mammary carcinoma progression by Th17-dependent mechanisms SV Novitskiy, MW Pickup, AE Gorska, P Owens, A Chytil, M Aakre, H Wu, ... Cancer discovery 1 (5), 430-441, 2011 | 157 | 2011 |
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional … AH Mekhdjian, FB Kai, MG Rubashkin, LS Prahl, LM Przybyla, ... Molecular biology of the cell 28 (11), 1467-1488, 2017 | 138 | 2017 |
Role of TGF-β signaling in generation of CD39+ CD73+ myeloid cells in tumors SV Ryzhov, MW Pickup, A Chytil, AE Gorska, Q Zhang, P Owens, ... The Journal of Immunology 193 (6), 3155-3164, 2014 | 122 | 2014 |
Inhibition of BMP signaling suppresses metastasis in mammary cancer P Owens, MW Pickup, SV Novitskiy, JM Giltnane, AE Gorska, CR Hopkins, ... Oncogene 34 (19), 2437-2449, 2015 | 115 | 2015 |
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators P Owens, MW Pickup, SV Novitskiy, A Chytil, AE Gorska, ME Aakre, ... Proceedings of the National Academy of Sciences 109 (8), 2814-2819, 2012 | 94 | 2012 |
Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties SV Novitskiy, MW Pickup, A Chytil, D Polosukhina, P Owens, HL Moses Journal of leukocyte biology 92 (3), 641-651, 2012 | 92 | 2012 |
ALCAM/CD166 Is a TGF-β–responsive marker and functional regulator of prostate cancer metastasis to bone AG Hansen, SA Arnold, M Jiang, TD Palmer, T Ketova, A Merkel, ... Cancer research 74 (5), 1404-1415, 2014 | 89 | 2014 |
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression EC Woods, FB Kai, JM Barnes, K Pedram, MW Pickup, MJ Hollander, ... Elife 6, e25752, 2017 | 81 | 2017 |
Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk LA Matise, TD Palmer, WJ Ashby, A Nashabi, A Chytil, M Aakre, ... Breast cancer research 14, 1-18, 2012 | 81 | 2012 |
TGF-β, bone morphogenetic protein, and activin signaling and the tumor microenvironment MW Pickup, P Owens, HL Moses Cold Spring Harbor perspectives in biology 9 (5), a022285, 2017 | 67 | 2017 |
Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases AL Bates, MW Pickup, MA Hallett, EA Dozier, S Thomas, B Fingleton The Journal of pathology 235 (5), 773-783, 2015 | 64 | 2015 |
Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer B Jovanović, JS Beeler, MW Pickup, A Chytil, AE Gorska, WJ Ashby, ... Breast Cancer Research 16, 1-14, 2014 | 64 | 2014 |
α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site YA Miroshnikova, GI Rozenberg, L Cassereau, M Pickup, JK Mouw, G Ou, ... Molecular biology of the cell 28 (22), 2958-2977, 2017 | 63 | 2017 |