| Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2 B Xia, Q Sheng, K Nakanishi, A Ohashi, J Wu, N Christ, X Liu, M Jasin, ... Molecular cell 22 (6), 719-729, 2006 | 1056 | 2006 |
| Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells A Ohashi, M Ohori, K Iwai, Y Nakayama, T Nambu, D Morishita, ... Nature communications 6 (1), 7668, 2015 | 206 | 2015 |
| Functional evaluation and cancer risk assessment of BRCA2 unclassified variants K Wu, SR Hinson, A Ohashi, D Farrugia, P Wendt, SV Tavtigian, ... Cancer research 65 (2), 417-426, 2005 | 161 | 2005 |
| TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma K Nakayama, MM Szewczyk, C dela Sena, H Wu, A Dong, H Zeng, F Li, ... Oncotarget 9 (26), 18480, 2018 | 106 | 2018 |
| Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2-and RAD51-associated homologous recombination in response to DNA damage A Ohashi, MZ Zdzienicka, J Chen, FJ Couch Journal of Biological Chemistry 280 (15), 14877-14883, 2005 | 104* | 2005 |
| Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice M Rowley, A Ohashi, G Mondal, L Mills, L Yang, L Zhang, R Sundsbak, ... Gastroenterology 140 (4), 1303-1313. e3, 2011 | 90 | 2011 |
| Combination treatment with a PI3K/Akt/mTOR pathway inhibitor overcomes resistance to anti-HER2 therapy in PIK3CA-mutant HER2-positive breast cancer cells Y Fujimoto, TY Morita, A Ohashi, H Haeno, Y Hakozaki, M Fujii, ... Scientific reports 10 (1), 21762, 2020 | 72 | 2020 |
| TAS6417/CLN-081 Is a Pan-Mutation–Selective EGFR Tyrosine Kinase Inhibitor with a Broad Spectrum of Preclinical Activity against Clinically Relevant EGFR Mutations H Udagawa, S Hasako, A Ohashi, R Fujioka, Y Hakozaki, M Shibuya, ... Molecular Cancer Research 17 (11), 2233-2243, 2019 | 67 | 2019 |
| Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor K Iwai, T Nambu, R Dairiki, M Ohori, J Yu, K Burke, M Gotou, Y Yamamoto, ... Science advances 5 (5), eaav3660, 2019 | 62 | 2019 |
| Tex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpoint G Mondal, A Ohashi, L Yang, M Rowley, FJ Couch Molecular cell 45 (5), 680-695, 2012 | 62 | 2012 |
| Synthetic studies on centromere-associated protein-E (CENP-E) inhibitors: 2. Application of electrostatic potential map (EPM) and structure-based modeling to imidazo [1, 2-a … T Hirayama, M Okaniwa, H Banno, H Kakei, A Ohashi, K Iwai, M Ohori, ... Journal of medicinal chemistry 58 (20), 8036-8053, 2015 | 50 | 2015 |
| Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos N Minami, A Aizawa, R Ihara, M Miyamoto, A Ohashi, H Imai Biology of reproduction 69 (5), 1736-1742, 2003 | 50 | 2003 |
| Single-cell analyses reveal diverse mechanisms of resistance to EGFR tyrosine kinase inhibitors in lung cancer Y Kashima, D Shibahara, A Suzuki, K Muto, IS Kobayashi, D Plotnick, ... Cancer research 81 (18), 4835-4848, 2021 | 47 | 2021 |
| A novel time-dependent CENP-E inhibitor with potent antitumor activity A Ohashi, M Ohori, K Iwai, T Nambu, M Miyamoto, T Kawamoto, ... PloS one 10 (12), e0144675, 2015 | 43 | 2015 |
| Long-read sequencing for non-small-cell lung cancer genomes Y Sakamoto, L Xu, M Seki, TT Yokoyama, M Kasahara, Y Kashima, ... Genome research 30 (9), 1243-1257, 2020 | 36 | 2020 |
| Synthetic studies of centromere-associated protein-E (CENP-E) inhibitors: 1. Exploration of fused bicyclic core scaffolds using electrostatic potential map T Hirayama, M Okaniwa, T Imada, A Ohashi, M Ohori, K Iwai, K Mori, ... Bioorganic & medicinal chemistry 21 (17), 5488-5502, 2013 | 34 | 2013 |
| Nuclear accumulation of cyclin B1 in mouse two-cell embryos is controlled by the activation of Cdc2 A Ohashi, N Minami, H Imai Biology of reproduction 65 (4), 1195-1200, 2001 | 26 | 2001 |
| Potentiality of multiple modalities for single-cell analyses to evaluate the tumor microenvironment in clinical specimens Y Kashima, Y Togashi, S Fukuoka, T Kamada, T Irie, A Suzuki, ... Scientific reports 11 (1), 341, 2021 | 24 | 2021 |
| Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active … O Kurasawa, T Miyazaki, M Homma, Y Oguro, T Imada, N Uchiyama, ... Journal of Medicinal Chemistry 63 (3), 1084-1104, 2020 | 24 | 2020 |
| Spontaneous vulvar papillomas in a colony of mice used for pancreatic cancer research NM Gades, A Ohashi, LD Mills, MA Rowley, KS Predmore, RJ Marler, ... Comparative medicine 58 (3), 271-275, 2008 | 21 | 2008 |
