Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women: a randomized crossover trial D Zambón, J Sabaté, S Munoz, B Campero, E Casals, M Merlos, ... Annals of internal medicine 132 (7), 538-546, 2000 | 479 | 2000 |
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells T Coll, E Eyre, R Rodríguez-Calvo, X Palomer, RM Sánchez, M Merlos, ... Journal of biological chemistry 283 (17), 11107-11116, 2008 | 419 | 2008 |
New Azole Antifungals. 3. Synthesis and Antifungal Activity of 3-Substituted-4(3H)-quinazolinones J Bartroli, E Turmo, M Algueró, E Boncompte, ML Vericat, L Conte, ... Journal of medicinal chemistry 41 (11), 1869-1882, 1998 | 285 | 1998 |
Synthesis and SAR of a New Series of COX-2-Selective Inhibitors: Pyrazolo[1,5-a]pyrimidines C Almansa, AF de Arriba, FL Cavalcanti, LA Gómez, A Miralles, M Merlos, ... Journal of medicinal chemistry 44 (3), 350-361, 2001 | 235 | 2001 |
Palmitate induces tumor necrosis factor-α expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-κB activation M Jové, A Planavila, RM Sánchez, M Merlos, JC Laguna, ... Endocrinology 147 (1), 552-561, 2006 | 217 | 2006 |
Pharmacological properties of S1RA, a new sigma‐1 receptor antagonist that inhibits neuropathic pain and activity‐induced spinal sensitization L Romero, D Zamanillo, X Nadal, R Sánchez‐Arroyos, I Rivera‐Arconada, ... British journal of pharmacology 166 (8), 2289-2306, 2012 | 208 | 2012 |
Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF) M Merlos, M Giral, D Balsa, R Ferrando, M Queralt, A Puigdemont, ... Journal of Pharmacology and Experimental Therapeutics 280 (1), 114-121, 1997 | 200 | 1997 |
Palmitate-mediated downregulation of peroxisome proliferator–activated receptor-γ coactivator 1α in skeletal muscle cells involves MEK1/2 and nuclear factor-κB activation T Coll, M Jové, R Rodríguez-Calvo, E Eyre, X Palomer, RM Sánchez, ... Diabetes 55 (10), 2779-2787, 2006 | 183 | 2006 |
Synthesis and structure− activity relationship of a new series of COX-2 selective inhibitors: 1, 5-diarylimidazoles C Almansa, J Alfón, AF de Arriba, FL Cavalcanti, I Escamilla, LA Gómez, ... Journal of medicinal chemistry 46 (16), 3463-3475, 2003 | 181 | 2003 |
Sigma 1 receptor: a new therapeutic target for pain D Zamanillo, L Romero, M Merlos, JM Vela European Journal of Pharmacology 716 (1-3), 78-93, 2013 | 158 | 2013 |
Activation of peroxisome proliferator–activated receptor β/δ inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-κB activity via … R Rodriguez-Calvo, L Serrano, T Coll, N Moullan, RM Sánchez, M Merlos, ... Diabetes 57 (8), 2149-2157, 2008 | 151 | 2008 |
Synthesis and Biological Evaluation of the 1-Arylpyrazole Class of σ1 Receptor Antagonists: Identification of 4-{2-[5-Methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy … JL Díaz, R Cuberes, J Berrocal, M Contijoch, U Christmann, A Fernández, ... Journal of medicinal chemistry 55 (19), 8211-8224, 2012 | 143 | 2012 |
Rupatadine: a new selective histamine H1 receptor and platelet-activating factor (PAF) antagonist. A review of pharmacological profile and clinical management of allergic rhinitis. I Izquierdo, M Merlos, J García-Rafanell Drugs of today (Barcelona, Spain: 1998) 39 (6), 451-468, 2003 | 126 | 2003 |
PPARβ/δ activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells D Álvarez-Guardia, X Palomer, T Coll, L Serrano, R Rodríguez-Calvo, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2011 | 100 | 2011 |
Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects A Vidal-Torres, B De La Puente, M Rocasalbas, C Touriño, SA Bura, ... European journal of pharmacology 711 (1-3), 63-72, 2013 | 94 | 2013 |
Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment L Vilà, A Rebollo, GS Ađalsteisson, M Alegret, M Merlos, N Roglans, ... Toxicology and applied pharmacology 251 (1), 32-40, 2011 | 94 | 2011 |
Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction M Rodríguez-Muñoz, P Sánchez-Blázquez, M Merlos, J Garzón-Niño Oncotarget 7 (34), 55840, 2016 | 89 | 2016 |
Modulation of peripheral μ-opioid analgesia by σ1 receptors C Sánchez-Fernández, Á Montilla-García, R González-Cano, FR Nieto, ... Journal of Pharmacology and Experimental Therapeutics 348 (1), 32-45, 2014 | 89 | 2014 |
The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control M Rodríguez-Muñoz, P Sánchez-Blázquez, R Herrero-Labrador, ... Antioxidants & redox signaling 22 (10), 799-818, 2015 | 85 | 2015 |
Walnut-enriched diet increases the association of LDL from hypercholesterolemic men with human HepG2 cells S Muñoz, M Merlos, D Zambón, C Rodríguez, J Sabaté, E Ros, ... Journal of lipid research 42 (12), 2069-2076, 2001 | 83 | 2001 |