De novo induction of amyloid-β deposition in vivo R Morales, C Duran-Aniotz, J Castilla, LD Estrada, C Soto Molecular psychiatry 17 (12), 1347-1353, 2012 | 241 | 2012 |
Crossing the species barrier by PrP Sc replication in vitro generates unique infectious prions J Castilla, D Gonzalez-Romero, P Saá, R Morales, J De Castro, C Soto Cell 134 (5), 757-768, 2008 | 236 | 2008 |
Molecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseases R Morales, LD Estrada, R Diaz-Espinoza, D Morales-Scheihing, MC Jara, ... The Journal of Neuroscience 30 (13), 4528-4535, 2010 | 235 | 2010 |
Cell‐free propagation of prion strains J Castilla, R Morales, P Saá, M Barria, P Gambetti, C Soto The EMBO journal 27 (19), 2557-2566, 2008 | 231 | 2008 |
Cross-seeding of misfolded proteins: implications for etiology and pathogenesis of protein misfolding diseases R Morales, I Moreno-Gonzalez, C Soto PLoS Pathog 9 (9), e1003537, 2013 | 228 | 2013 |
The prion strain phenomenon: molecular basis and unprecedented features R Morales, K Abid, C Soto Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (6), 681-691, 2007 | 224 | 2007 |
Protein misfolding cyclic amplification for diagnosis and prion propagation studies J Castilla, P Saá, R Morales, K Abid, K Maundrell, C Soto Methods in enzymology 412, 3-21, 2006 | 189 | 2006 |
Isolation and characterization of a proteinase K-sensitive PrPSc fraction MA Pastrana, G Sajnani, B Onisko, J Castilla, R Morales, C Soto, ... Biochemistry 45 (51), 15710-15717, 2006 | 187 | 2006 |
De novo generation of infectious prions in vitro produces a new disease phenotype MA Barria, A Mukherjee, D Gonzalez-Romero, R Morales, C Soto PLoS Pathog 5 (5), e1000421, 2009 | 182 | 2009 |
Grass Plants Bind, Retain, Uptake, and Transport Infectious Prions S Pritzkow, R Morales, F Moda, U Khan, GC Telling, E Hoover, C Soto Cell reports 11 (8), 1168-1175, 2015 | 162 | 2015 |
Detection of infectious prions in urine D Gonzalez-Romero, MA Barria, P Leon, R Morales, C Soto FEBS letters 582 (21-22), 3161-3166, 2008 | 148 | 2008 |
Protein misfolding cyclic amplification of infectious prions R Morales, C Duran-Aniotz, R Diaz-Espinoza, MV Camacho, C Soto Nature protocols 7 (7), 1397-1409, 2012 | 147 | 2012 |
Estimating prion concentration in fluids and tissues by quantitative PMCA B Chen, R Morales, MA Barria, C Soto Nature methods 7 (7), 519-520, 2010 | 137 | 2010 |
The endoplasmic reticulum chaperone GRP78/BiP modulates prion propagation in vitro and in vivo KW Park, GE Kim, R Morales, F Moda, I Moreno-Gonzalez, ... Scientific Reports 7, 44723, 2017 | 107 | 2017 |
Cross currents in protein misfolding disorders: interactions and therapy R Morales, KM Green, C Soto CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2009 | 86 | 2009 |
Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein W Gomez, R Morales, V Maracaja-Coutinho, V Parra, M Nassif Aging (Albany NY) 12 (1), 1011, 2020 | 82 | 2020 |
Prion protein glycosylation is not required for strain-specific neurotropism JR Piro, BT Harris, K Nishina, C Soto, R Morales, JR Rees, ... Journal of virology 83 (11), 5321-5328, 2009 | 80 | 2009 |
Prion strains in mammals: Different conformations leading to disease R Morales PLoS Pathogens 13 (7), e1006323, 2017 | 79 | 2017 |
Cellular factors implicated in prion replication K Abid, R Morales, C Soto FEBS letters 584 (11), 2409-2414, 2010 | 77 | 2010 |
Prion-like features of misfolded Aβ and tau aggregates R Morales, K Callegari, C Soto Virus research 207, 106-112, 2015 | 69 | 2015 |