A statistical method for identifying differential gene–gene co-expression patterns Y Lai, B Wu, L Chen, H Zhao Bioinformatics 20 (17), 3146-3155, 2004 | 201 | 2004 |
Comparison of single-nucleotide polymorphisms and microsatellites in inference of population structure N Liu, L Chen, S Wang, C Oh, H Zhao Bmc Genetics 6, 1-5, 2005 | 194 | 2005 |
A two-parameter generalized Poisson model to improve the analysis of RNA-seq data S Srivastava, L Chen Nucleic acids research 38 (17), e170-e170, 2010 | 188 | 2010 |
miRNA biomarkers in breast cancer detection and management SW Fu, L Chen, Y Man Journal of Cancer 2, 116, 2011 | 150 | 2011 |
Role of deregulated microRNAs in breast cancer progression using FFPE tissue L Chen, Y Li, Y Fu, J Peng, MH Mo, M Stamatakos, CB Teal, RF Brem, ... PloS one 8 (1), e54213, 2013 | 121 | 2013 |
PTBP1 and PTBP2 serve both specific and redundant functions in neuronal pre-mRNA splicing JK Vuong, CH Lin, M Zhang, L Chen, DL Black, S Zheng Cell reports 17 (10), 2766-2775, 2016 | 116 | 2016 |
Co-expression network analysis identified FCER1G in association with progression and prognosis in human clear cell renal cell carcinoma L Chen, L Yuan, Y Wang, G Wang, Y Zhu, R Cao, G Qian, C Xie, X Liu, ... International Journal of Biological Sciences 13 (11), 1361, 2017 | 114 | 2017 |
Role of β-catenin and TCF/LEF family members in transcriptional activity of HIV in astrocytes SD Narasipura, LJ Henderson, SW Fu, L Chen, F Kashanchi, L Al-Harthi Journal of virology 86 (4), 1911-1921, 2012 | 101 | 2012 |
miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer X Tan, Y Fu, L Chen, W Lee, Y Lai, K Rezaei, S Tabbara, P Latham, ... Oncotarget 7 (1), 293, 2016 | 97 | 2016 |
GC content around splice sites affects splicing through pre-mRNA secondary structures J Zhang, CCJ Kuo, L Chen BMC genomics 12, 1-11, 2011 | 97 | 2011 |
Transcriptional trajectories of human kidney injury progression PE Cippà, B Sun, J Liu, L Chen, M Naesens, AP McMahon JCI insight 3 (22), 2018 | 95 | 2018 |
Alternative splicing: Human disease and quantitative analysis from high-throughput sequencing W Jiang, L Chen Computational and structural biotechnology journal 19, 183-195, 2021 | 94 | 2021 |
Mitotic regulator Mis18β interacts with and specifies the centromeric assembly of molecular chaperone holliday junction recognition protein (HJURP) J Wang, X Liu, Z Dou, L Chen, H Jiang, C Fu, G Fu, D Liu, J Zhang, T Zhu, ... Journal of Biological Chemistry 289 (12), 8326-8336, 2014 | 94 | 2014 |
Protein–DNA interaction mapping using genomic tiling path microarrays in Drosophila LV Sun, L Chen, F Greil, N Negre, TR Li, G Cavalli, H Zhao, ... Proceedings of the National Academy of Sciences 100 (16), 9428-9433, 2003 | 90 | 2003 |
Co-expression network analysis identified six hub genes in association with progression and prognosis in human clear cell renal cell carcinoma (ccRCC) L Yuan, L Chen, K Qian, G Qian, CL Wu, X Wang, Y Xiao Genomics data 14, 132-140, 2017 | 82 | 2017 |
Deep soft K-means clustering with self-training for single-cell RNA sequence data L Chen, W Wang, Y Zhai, M Deng NAR genomics and bioinformatics 2 (2), lqaa039, 2020 | 79 | 2020 |
TM4SF1 regulates apoptosis, cell cycle and ROS metabolism via the PPARγ-SIRT1 feedback loop in human bladder cancer cells R Cao, G Wang, K Qian, L Chen, L Ju, G Qian, CL Wu, HC Dan, W Jiang, ... Cancer letters 414, 278-293, 2018 | 72 | 2018 |
Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis L Yuan, B Shu, L Chen, K Qian, Y Wang, G Qian, Y Zhu, X Cao, C Xie, ... Oncotarget 8 (41), 70508, 2017 | 68 | 2017 |
Characterization and comparison of human nuclear and cytosolic editomes L Chen Proceedings of the National Academy of Sciences 110 (29), E2741-E2747, 2013 | 68 | 2013 |
Axonogenesis is coordinated by neuron-specific alternative splicing programming and splicing regulator PTBP2 M Zhang, V Ergin, L Lin, C Stork, L Chen, S Zheng Neuron 101 (4), 690-706. e10, 2019 | 66 | 2019 |