Type I interferons in host defense DB Stetson, R Medzhitov Immunity 25 (3), 373-381, 2006 | 1452 | 2006 |
Trex1 prevents cell-intrinsic initiation of autoimmunity DB Stetson, JS Ko, T Heidmann, R Medzhitov Cell 134 (4), 587-598, 2008 | 1313 | 2008 |
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response DB Stetson, R Medzhitov Immunity 24 (1), 93-103, 2006 | 1235 | 2006 |
Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response GI Rice, J Bond, A Asipu, RL Brunette, IW Manfield, IM Carr, JC Fuller, ... Nature genetics 41 (7), 829-832, 2009 | 794 | 2009 |
Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function DB Stetson, M Mohrs, RL Reinhardt, JL Baron, ZE Wang, L Gapin, ... The Journal of experimental medicine 198 (7), 1069-1076, 2003 | 790 | 2003 |
Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease A Gall, P Treuting, KB Elkon, YM Loo, M Gale Jr, GN Barber, DB Stetson Immunity 36 (1), 120-131, 2012 | 528 | 2012 |
DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway L Lau, EE Gray, RL Brunette, DB Stetson Science 350 (6260), 568-571, 2015 | 454 | 2015 |
Isoforms of RNA-editing enzyme ADAR1 independently control nucleic acid sensor MDA5-driven autoimmunity and multi-organ development K Pestal, CC Funk, JM Snyder, ND Price, PM Treuting, DB Stetson Immunity 43 (5), 933-944, 2015 | 432 | 2015 |
Limiting cholesterol biosynthetic flux spontaneously engages type I IFN signaling AG York, KJ Williams, JP Argus, QD Zhou, G Brar, L Vergnes, EE Gray, ... Cell 163 (7), 1716-1729, 2015 | 386 | 2015 |
Cutting edge: cGAS is required for lethal autoimmune disease in the Trex1-deficient mouse model of Aicardi–Goutières syndrome EE Gray, PM Treuting, JJ Woodward, DB Stetson The Journal of Immunology 195 (5), 1939-1943, 2015 | 368 | 2015 |
Mouse Vα14i natural killer T cells are resistant to cytokine polarization in vivo JL Matsuda, L Gapin, JL Baron, S Sidobre, DB Stetson, M Mohrs, ... Proceedings of the National Academy of Sciences 100 (14), 8395-8400, 2003 | 338 | 2003 |
The enemy within: endogenous retroelements and autoimmune disease HE Volkman, DB Stetson Nature immunology 15 (5), 415-422, 2014 | 287 | 2014 |
The type I interferonopathies: 10 years on YJ Crow, DB Stetson Nature Reviews Immunology 22 (8), 471-483, 2022 | 245 | 2022 |
Extensive evolutionary and functional diversity among mammalian AIM2-like receptors RL Brunette, JM Young, DG Whitley, IE Brodsky, HS Malik, DB Stetson Journal of Experimental Medicine 209 (11), 1969-1983, 2012 | 242 | 2012 |
Tight nuclear tethering of cGAS is essential for preventing autoreactivity HE Volkman, S Cambier, EE Gray, DB Stetson Elife 8, e47491, 2019 | 234 | 2019 |
The AIM2-like receptors are dispensable for the interferon response to intracellular DNA EE Gray, D Winship, JM Snyder, SJ Child, AP Geballe, DB Stetson Immunity 45 (2), 255-266, 2016 | 208 | 2016 |
Intracellular nucleic acid detection in autoimmunity JT Crowl, EE Gray, K Pestal, HE Volkman, DB Stetson Annual review of immunology 35 (1), 313-336, 2017 | 204 | 2017 |
The SKIV2L RNA exosome limits activation of the RIG-I-like receptors SC Eckard, GI Rice, A Fabre, C Badens, EE Gray, JL Hartley, YJ Crow, ... Nature immunology 15 (9), 839-845, 2014 | 200 | 2014 |
Activation of the integrated stress response during T helper cell differentiation S Scheu, DB Stetson, RL Reinhardt, JH Leber, M Mohrs, RM Locksley Nature immunology 7 (6), 644-651, 2006 | 191 | 2006 |
Human DNA-PK activates a STING-independent DNA sensing pathway K Burleigh, JH Maltbaek, S Cambier, R Green, M Gale Jr, RC James, ... Science immunology 5 (43), eaba4219, 2020 | 152 | 2020 |