Structural biology of the Bcl-2 family of proteins AM Petros, ET Olejniczak, SW Fesik Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1644 (2-3), 83-94, 2004 | 1061 | 2004 |
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain Z Liu, C Sun, ET Olejniczak, RP Meadows, SF Betz, T Oost, J Herrmann, ... Nature 408 (6815), 1004-1008, 2000 | 865 | 2000 |
Discovery of small molecules that bind to K‐Ras and inhibit Sos‐mediated activation Q Sun, JP Burke, J Phan, MC Burns, ET Olejniczak, AG Waterson, T Lee, ... Angewandte Chemie International Edition 51 (25), 6140-6143, 2012 | 551 | 2012 |
Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies AM Petros, DG Nettesheim, Y Wang, ET Olejniczak, RP Meadows, J Mack, ... Protein Science 9 (12), 2528-2534, 2000 | 547 | 2000 |
One-dimensional relaxation-and diffusion-edited NMR methods for screening compounds that bind to macromolecules PJ Hajduk, ET Olejniczak, SW Fesik Journal of the American Chemical Society 119 (50), 12257-12261, 1997 | 539 | 1997 |
NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain B Huang, M Eberstadt, ET Olejniczak, RP Meadows, SW Fesik Nature 384 (6610), 638-641, 1996 | 530 | 1996 |
Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer TK Oost, C Sun, RC Armstrong, AS Al-Assaad, SF Betz, TL Deckwerth, ... Journal of medicinal chemistry 47 (18), 4417-4426, 2004 | 502 | 2004 |
Discovery of potent nonpeptide inhibitors of stromelysin using SAR by NMR PJ Hajduk, G Sheppard, DG Nettesheim, ET Olejniczak, SB Shuker, ... Journal of the American Chemical Society 119 (25), 5818-5827, 1997 | 470 | 1997 |
Structure and ligand recognition of the phosphotyrosine binding domain of Shc MM Zhou, KS Ravichandran, ET Olejniczak, AM Petros, RP Meadows, ... Nature 378 (6557), 584-592, 1995 | 467 | 1995 |
Structural characterization of a soluble amyloid β-peptide oligomer L Yu, R Edalji, JE Harlan, TF Holzman, AP Lopez, B Labkovsky, H Hillen, ... Biochemistry 48 (9), 1870-1877, 2009 | 453 | 2009 |
Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure … G Liu, JR Huth, ET Olejniczak, R Mendoza, P DeVries, S Leitza, EB Reilly, ... Journal of medicinal chemistry 44 (8), 1202-1210, 2001 | 421 | 2001 |
Analysis of deuterium nuclear magnetic resonance line shapes in anisotropic media RJ Wittebort, ET Olejniczak, RG Griffin The Journal of chemical physics 86 (10), 5411-5420, 1987 | 403 | 1987 |
A general method for assigning NMR spectra of denatured proteins using 3D HC (CO) NH-TOCSY triple resonance experiments TM Logan, ET Olejniczak, RX Xu, SW Fesik Journal of biomolecular NMR 3, 225-231, 1993 | 361 | 1993 |
Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design A Friberg, D Vigil, B Zhao, RN Daniels, JP Burke, PM Garcia-Barrantes, ... Journal of medicinal chemistry 56 (1), 15-30, 2013 | 320 | 2013 |
A novel MCL1 inhibitor combined with venetoclax rescues venetoclax-resistant acute myelogenous leukemia HE Ramsey, MA Fischer, T Lee, AE Gorska, MP Arrate, L Fuller, KL Boyd, ... Cancer discovery 8 (12), 1566-1581, 2018 | 305 | 2018 |
Structure of the N-terminal RNA-binding domain of the SARS CoV nucleocapsid protein Q Huang, L Yu, AM Petros, A Gunasekera, Z Liu, N Xu, P Hajduk, J Mack, ... Biochemistry 43 (20), 6059-6063, 2004 | 299 | 2004 |
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC LR Thomas, Q Wang, BC Grieb, J Phan, AM Foshage, Q Sun, ... Molecular cell 58 (3), 440-452, 2015 | 288 | 2015 |
Solution structure of a pleckstrin-homology domain HS Yoon, PJ Hajduk, AM Petros, ET Olejniczak, RP Meadows, SW Fesik Nature 369 (6482), 672-675, 1994 | 270 | 1994 |
ALARM NMR: a rapid and robust experimental method to detect reactive false positives in biochemical screens JR Huth, R Mendoza, ET Olejniczak, RW Johnson, DA Cothron, Y Liu, ... Journal of the American Chemical Society 127 (1), 217-224, 2005 | 250 | 2005 |
NMR studies of [U-13C] cyclosporin A bound to cyclophilin: bound conformation and portions of cyclosporin involved in binding SW Fesik, RT Gampe Jr, HL Eaton, G Gemmecker, ET Olejniczak, P Neri, ... Biochemistry 30 (26), 6574-6583, 1991 | 245 | 1991 |