Dual allosteric activation mechanisms in monomeric human glucokinase AC Whittington, M Larion, JM Bowler, KM Ramsey, R Brüschweiler, ... Proceedings of the National Academy of Sciences 112 (37), 11553-11558, 2015 | 66 | 2015 |
A single mutation unlocks cascading exaptations in the origin of a potent pitviper neurotoxin AC Whittington, AJ Mason, DR Rokyta Molecular Biology and Evolution 35 (4), 887-898, 2018 | 37 | 2018 |
Nanosecond-timescale dynamics and conformational heterogeneity in human GCK regulation and disease SM Sternisha, AC Whittington, JAM Fiesco, C Porter, MM McCray, ... Biophysical journal 118 (5), 1109-1118, 2020 | 9 | 2020 |
Resurrecting prehistoric parvalbumins to explore the evolution of thermal compensation in extant Antarctic fish parvalbumins AC Whittington, TS Moerland Journal of Experimental Biology 215 (18), 3281-3292, 2012 | 9 | 2012 |
The Chemosensory Repertoire of the Eastern Diamondback Rattlesnake (Crotalus adamanteus) Reveals Complementary Genetics of Olfactory and Vomeronasal … MP Hogan, AC Whittington, MB Broe, MJ Ward, HL Gibbs, DR Rokyta Journal of Molecular Evolution 89, 313-328, 2021 | 7 | 2021 |
Biophysical spandrels form a hot-spot for kosmotropic mutations in bacteriophage thermal adaptation AC Whittington, DR Rokyta Journal of Molecular Evolution 87, 27-36, 2019 | 4 | 2019 |
Functional and structural characterization of a eurytolerant calsequestrin from the intertidal teleost Fundulus heteroclitus AC Whittington, TE Nienow, CL Whittington, TJ Fort, TJ Grove Plos one 7 (11), e50801, 2012 | 2 | 2012 |
Recruitment of a Middling Promiscuous Enzyme Drives Adaptive Metabolic Evolution in Escherichia coli RP Campbell, AC Whittington, DAR Zorio, BG Miller Molecular Biology and Evolution 40 (9), msad202, 2023 | 1 | 2023 |
Vertical Investigations of Enzyme Evolution Using Ancestral Sequence Reconstruction AC Whittington, S Kamalaldinezabadi, JI Santiago, BG Miller Elsevier, 2020 | 1 | 2020 |
Ancestral sequence reconstruction and homology modeling link temperature adaptation and conservation of function with sequence evolution in parvalbumin AC Whittington, TS Moerland Biophysical Journal 96 (3), 651a, 2009 | 1 | 2009 |
Molecular basis for cA6 synthesis by a type III-A CRISPR–Cas enzyme and its conversion to cA4 production HN Goswami, F Ahmadizadeh, B Wang, D Addo-Yobo, Y Zhao, ... Nucleic Acids Research 52 (17), 10619-10629, 2024 | | 2024 |
Cardiac troponin C N-helix deletion in mouse heart Y Shi, MO Assibey, MCR Garcia, AC Whittington, H He, VE Galkin, ... Biophysical Journal 123 (3), 17a, 2024 | | 2024 |
Biochemical methods to map and quantify allosteric motions in human glucokinase BH Gordon, P Liu, AC Whittington, R Silvers, BG Miller Methods in enzymology 685, 433-459, 2023 | | 2023 |
Evolutionary origins of a heteromeric protein-protein interaction that regulates mammalian glucose homeostasis JI Santiago, AC Whittington, BG Miller Biophysical Journal 121 (3), 18a, 2022 | | 2022 |
Evolutionary origins of redox sensitivity in glucokinases JE Papa, AC Whittington, BG Miller Biophysical Journal 121 (3), 451a, 2022 | | 2022 |
The genetic basis of sensory perception in pitvipers M Hogan, AC Whittington, DR Rokyta Toxicon 182, S31-S31, 2020 | | 2020 |
From Muscle to Molecule: Function and Structure of the Calcium-Binding Protein Calsequestrin from a Eurythermal Teleost TJ Grove, AC Whittington, TE Nienow, CL Whittington, TJ Fort INTEGRATIVE AND COMPARATIVE BIOLOGY 53, E83-E83, 2013 | | 2013 |
Time Travel in the Lab: Exploring Thermal Compensation in Antarctic Fish Parvalbumins TS Moerland, AC Whittington INTEGRATIVE AND COMPARATIVE BIOLOGY 53, E148-E148, 2013 | | 2013 |
The evolution of thermal compensation in Antarctic fish parvalbumins AC Whittington The Florida State University, 2011 | | 2011 |
Homology model of Fundulus heteroclitus calsequestrin reveals structural differences that may contribute to thermal adaptation of F. heteroclitus TE Nienow, AC Whittington, TJ Grove INTEGRATIVE AND COMPARATIVE BIOLOGY 50, E274-E274, 2010 | | 2010 |