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Penny Lovat
Penny Lovat
Professor of Cellular Dermatology and Oncology , Newcastle University
在 ncl.ac.uk 的电子邮件经过验证
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AMBRA1 levels predict resistance to MAPK inhibitors in melanoma
L Di Leo, C Pagliuca, A Kishk, S Rizza, C Tsiavou, C Pecorari, C Dahl, ...
Proceedings of the National Academy of Sciences 121 (25), e2400566121, 2024
2024
Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
G Kelly, T Kataura, J Panek, G Ma, H Salmonowicz, A Davis, H Kendall, ...
Dev Cell 59 (10.1016), 2024
12024
The combined immunohistochemical expression of AMBRA1 and SQSTM1 identifies patients with poorly differentiated cutaneous squamous cell carcinoma at risk of metastasis: A proof …
MH Alexander, WJ Cousins, T Ewen, AP South, P Lovat, N Stefanos
Journal of Cutaneous Pathology 51 (6), 450-458, 2024
2024
Porcine‐derived collagen peptides promote re‐epithelialisation through activation of integrin signalling
K Mistry, G Richardson, S Vleminckx, R Smith, E Gevaert, PE Lovat
Wound Repair and Regeneration, 2024
2024
Método in vitro para determinar se um sujeito com melanoma tem um risco maior de desenvolver metástase
M Labus, P Lovat, R Ellis
2024
AMBRA1 is a predictive biomarker of melanoma response to targeted therapy
L Di Leo, C Pagliuca, A Kishk, S Rizza, C Tsiavou, C Pecorari, C Dahl, ...
EJC Skin Cancer 2, 2024
2024
Loss of AMBRA1 expression in the tumour endothelium as a potential biomarker to identify AJCC stage I/II melanomas at high risk of metastasis
P Lovat, R Stout, K Best, P Sloan, J Armstrong
EJC Skin Cancer 2, 2024
2024
Immunohistochemical analysis of AMBRA1 and loricrin expression reveals maintained expression in the epidermis overlying a range of benign melanocytic naevi but which may be …
A Husain, P Lovat, G Richardson, T Ness, C Jones, C Graham, M Labus, ...
EJC Skin Cancer 2, 2024
2024
Validation of Epidermal AMBRA1 and Loricrin (AMBLor) as a prognostic biomarker for non-ulcerated AJCC stage I/II cutaneous melanoma
T Ewen, A Husain, N Stefanos, P Barrett, C Jones, T Ness, A Long, ...
British Journal of Dermatology, 2023
3*2023
Predictive accuracy of risk prediction models for recurrence, metastasis and survival for early-stage cutaneous melanoma: a systematic review
TP Kunonga, RPW Kenny, M Astin, A Bryant, V Kontogiannis, D Coughlan, ...
BMJ open 13 (9), e073306, 2023
22023
O17 Endogenous double-stranded RNA (dsRNA) in melanoma: an attack from within
S Sadeq, R Plummer, S Chitcharoen, P Lovat, G Nelson, A Werner
British Journal of Dermatology 189 (1), e11-e12, 2023
2023
Discovery and validation of AMBLor as a prognostic biomarker for non-ulcerated cutaneous AJCC stage I/II melanoma.
P Lovat, T Ewen, S Podlipnik, S Puig, J Malvehy, P Clark, C Lewis, ...
Journal of Clinical Oncology 41 (16_suppl), 9573-9573, 2023
2023
Performance analysis of four machine learning algorithms for the accurate prediction of metastatic disease in cutaneous squamous cell carcinoma.
TW Andrew, I Bolnykh, AL Bowes, SASG Fernando, A Nair, SNP Martin, ...
Journal of Clinical Oncology 41 (16_suppl), e13579-e13579, 2023
2023
Programmed cell death-1 receptor-mediated regulation of Tbet+NK1.1 innate lymphoid cells within the tumor microenvironment
JX Lim, CY Lai, GE Mallett, D McDonald, G Hulme, S Laba, A Shapanis, ...
Proceedings of the National Academy of Sciences 120 (18), e2216587120, 2023
52023
1235 Endothelial AMBRA1 and Claudin5 as potential biomarkers of metastases in early-stage melanoma
I Cosgarea, R Stout, K Best, P Sloan, J Armstrong, P Lovat
Journal of Investigative Dermatology 143 (5), S212, 2023
2023
Clinical management of oropharyngeal squamous cell carcinoma
P Lovat
US Patent App. 17/633,073, 2022
42022
463 Implications of the ds-RNA stress response in melanoma cell lines and patient samples
S Sadeq, P Lovat, G Nelson, D Mcdonald, A Filby, A Werner
Journal of Investigative Dermatology 142 (12), S260, 2022
2022
Biomarkers for disease progression in squamous cell carcinoma
M Labus, P Lovat, R Ellis, A Mcconnell
US Patent App. 17/594,939, 2022
2022
AMBLor: an immunohistochemical prognostic biomarker to identify low-risk nonulcerated cutaneous AJCC stage I/II melanomas
P Sloan, T Ewen, G Paragh, P Bogner, A Hussain, N Stefanos, P Barrett, ...
BRITISH JOURNAL OF DERMATOLOGY 187, 143-144, 2022
2022
Loss of epidermal integrity and tumour ulceration in melanoma is driven by tumoral transforming growth factor-beta 2 secretion and mediated through AMBRA1 and claudin-1 …
I Cosgarea, A McConnell, T Ewen, D Tang, A Greenwood, J Armstrong, ...
BRITISH JOURNAL OF DERMATOLOGY 187 (1), E2-E2, 2022
2022
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