关注
Joel S. Bader
Joel S. Bader
Professor, Biomedical Engineering, Johns Hopkins University; Founder, Neochromosome, Inc.
在 jhu.edu 的电子邮件经过验证 - 首页
标题
引用次数
年份
Prioritizing drug targets by perturbing biological network response functions
MC Perrone, MG Lerner, M Dunworth, AJ Ewald, JS Bader
PLOS Computational Biology 20 (6), e1012195, 2024
2024
Methods and compositions using an engineered release factor
L Mitchell, JS Bader
US Patent App. 18/501,724, 2024
2024
Longitudinal change in mitochondrial heteroplasmy exhibits positive selection for deleterious variants
LM Kuiper, W Shi, J Verlouw, YS Hong, P Arp, D Puiu, L Broer, J Xie, ...
medRxiv, 2024
2024
Ensemble Detection of DNA Engineering Signatures
A Adler, JS Bader, B Basnight, BW Booth, J Cai, E Cho, JH Collins, Y Ge, ...
ACS Synthetic Biology 13 (4), 1105-1115, 2024
12024
Proteomic Signature of HIV-Associated Subclinical Left Atrial Remodeling and Incident Heart Failure
TE Peterson, VS Hahn, R Moaddel, M Zhu, SA Haberlen, FJ Palella, ...
medRxiv, 2024.02. 13.24302797, 2024
2024
Manipulating the 3D organization of the largest synthetic yeast chromosome
W Zhang, L Lazar-Stefanita, H Yamashita, MJ Shen, LA Mitchell, ...
Molecular Cell 83 (23), 4424-4437. e5, 2023
152023
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
Y Zhao, C Coelho, AL Hughes, L Lazar-Stefanita, S Yang, AN Brooks, ...
Cell 186 (24), 5220-5236. e16, 2023
422023
Establishing chromosomal design-build-test-learn through a synthetic chromosome and its combinatorial reconfiguration
JL Foo, S Kitano, AV Susanto, Z Jin, Y Lin, Z Luo, L Huang, Z Liang, ...
Cell Genomics 3 (11), 2023
102023
Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defects
TC Williams, H Kroukamp, X Xu, ELI Wightman, B Llorente, AR Borneman, ...
Cell Genomics 3 (11), 2023
82023
Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics
BA Blount, X Lu, MRM Driessen, D Jovicevic, MI Sanchez, K Ciurkot, ...
Cell Genomics 3 (11), 2023
132023
Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains
LH McCulloch, V Sambasivam, AL Hughes, N Annaluru, S Ramalingam, ...
Cell Genomics 3 (11), 2023
92023
Context-dependent neocentromere activity in synthetic yeast chromosome VIII
S Lauer, J Luo, L Lazar-Stefanita, W Zhang, LH McCulloch, V Fanfani, ...
Cell Genomics 3 (11), 2023
112023
Dissecting aneuploidy phenotypes by constructing Sc2. 0 chromosome VII and SCRaMbLEing synthetic disomic yeast
Y Shen, F Gao, Y Wang, Y Wang, J Zheng, J Gong, J Zhang, Z Luo, ...
Cell genomics 3 (11), 2023
192023
Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function
J Luo, LA Vale-Silva, AR Raghavan, G Mercy, J Heldrich, X Sun, MK Li, ...
Cell Genomics 3 (11), 2023
152023
Proteomic Signatures of Human Immunodeficiency Virus-Associated Subclinical Left Atrial Dilation
TE Peterson, VS Hahn, S Haberlen, M Plankey, F Palella, J Bader, ...
Circulation 148 (Suppl_1), A15132-A15132, 2023
2023
Functional Whole Genome Screen of Nutrient-Starved Mycobacterium tuberculosis Identifies Genes Involved in Rifampin Tolerance
WM Matern, HT Harris, C Danchik, M McDonald, G Patel, A Srivastava, ...
Microorganisms 11 (9), 2269, 2023
2023
Pervasive RNA folding is crucial for narnavirus genome maintenance
M Fukuda, J Cai, JS Bader, JD Boeke
Proceedings of the National Academy of Sciences 120 (26), e2304082120, 2023
22023
Priors, population sizes, and power in genome-wide hypothesis tests
J Cai, J Zhan, DE Arking, JS Bader
BMC bioinformatics 24 (1), 170, 2023
22023
Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion
YJ Jeong, H Knutsdottir, F Shojaeian, MG Lerner, MF Wissler, E Henriet, ...
The Journal of clinical investigation 133 (8), 2023
52023
Next-generation large-scale binary protein interaction network for Drosophila melanogaster
HW Tang, K Spirohn, Y Hu, T Hao, IA Kovács, Y Gao, R Binari, ...
Nature communications 14 (1), 1-16, 2023
11*2023
系统目前无法执行此操作,请稍后再试。
文章 1–20