Intraputaminal AAV-CAv1. 3-shRNA Averts Levodopa-induced Dyskinesias and Ameliorates Long-standing Parkinsonian Motor Deficits in Aged Parkinsonian Macaques (S26. 009) M Caulfield, K Steece-Collier, MV Werp, S Muller, J Stancati, T Collier, ... Neurology 102 (17_supplement_1), 2673, 2024 | | 2024 |
Engineered Nanobodies With Programmable Target Antigen Proteolysis (Ptap) Fusions Regulate Intracellular Alpha-synuclein in Vitro and in Vivo D Chatterjee, LY D’Brant, BM Hiller, DJ Marmion, IM Sandoval, KC Luk, ... Research Square, 2024 | | 2024 |
“Advanced” Parkinson's disease: A review S Aslam, F Manfredsson, A Stokes, H Shill Parkinsonism & Related Disorders, 106065, 2024 | | 2024 |
IFNγ drives neuroinflammation, demyelination, and neurodegeneration in a mouse model of multiple system atrophy NJ Corbin-Stein, GM Childers, JM Webster, A Zane, YT Yang, N Mudium, ... Acta neuropathologica communications 12 (1), 11, 2024 | 1 | 2024 |
Devaluing memories of reward: A case for dopamine B Fry, N Russell, V Fex, B Mo, N Pence, J Beatty, F Manfredsson, B Toth, ... bioRxiv, 2024.01. 10.575106, 2024 | | 2024 |
Method of engineering and isolating adeno-associated virus F Manfredsson, I Sandoval US Patent App. 17/906,715, 2023 | | 2023 |
Nigral-specific increase in ser31 phosphorylation compensates for tyrosine hydroxylase protein and nigrostriatal neuron loss: Implications for delaying parkinsonian signs EA Kasanga, Y Han, MK Shifflet, W Navarrete, R McManus, C Parry, ... Experimental neurology 368, 114509, 2023 | 8 | 2023 |
Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy V Joers, BC Murray, C McLaughlin, D Oliver, H Staley, J Coronado, ... bioRxiv, 2023 | | 2023 |
Differential expression of RET and GDNF family receptor, GFR-α1, between striatum and substantia nigra following nigrostriatal lesion: A case for diminished GDNF-signaling EA Kasanga, Y Han, W Navarrete, R McManus, MK Shifflet, C Parry, ... Experimental neurology 366, 114435, 2023 | 4 | 2023 |
Systems and methods for treating levodopa dyskinesia, enhancing motor benefit, and delaying disease progression F Manfredsson, K Steece-Collier US Patent App. 17/998,128, 2023 | | 2023 |
Downregulation of striatal CaV1. 3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age ME Caulfield, MJ Vander Werp, JA Stancati, TJ Collier, CE Sortwell, ... Neurobiology of disease 181, 106111, 2023 | 2 | 2023 |
A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates DM Anwer, F Gubinelli, YA Kurt, L Sarauskyte, F Jacobs, C Venuti, ... Plos one 18 (5), e0284480, 2023 | 1 | 2023 |
Broad serotonergic actions of vortioxetine as a promising avenue for the treatment of L-DOPA-induced dyskinesia C Budrow, K Elder, M Coyle, A Centner, N Lipari, S Cohen, J Glinski, ... Cells 12 (6), 837, 2023 | 3 | 2023 |
Nicotine-mediated recruitment of GABAergic neurons to a dopaminergic phenotype attenuates motor deficits in an alpha-Synuclein Parkinson’s model JIC Lai, A Porcu, B Romoli, M Keisler, FP Manfredsson, SB Powell, ... International journal of molecular sciences 24 (4), 4204, 2023 | 5 | 2023 |
The role of Striatal Cav1. 3 calcium channels in therapeutics for Parkinson’s Disease ME Caulfield, FP Manfredsson, K Steece-Collier Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in …, 2023 | 4 | 2023 |
Engineering of glial-targeted AAVs for neurodegenerative disease IM Sandoval, JD Elsworth, FP Manfredsson CELL TRANSPLANTATION 32, 32-32, 2023 | | 2023 |
Characterisation of functional deficits induced by AAV overexpression of alpha-synuclein in rats F Gubinelli, L Sarauskyte, C Venuti, I Kulacz, G Cazzolla, M Negrini, ... Current Research in Neurobiology 4, 100065, 2023 | 3 | 2023 |
Characterizing the relationship between L-DOPA-induced-dyskinesia and psychosis-like behaviors in a bilateral rat model of Parkinson's disease N Lipari, A Centner, J Glinski, S Cohen, FP Manfredsson, C Bishop Neurobiology of disease 176, 105965, 2023 | 1 | 2023 |
IFNγ drives neuroinflammation and demyelination in a mouse model of multiple system atrophy NJ Gallups, GM Childers, JM Webster, A Zane, YT Yang, N Mudium, ... bioRxiv, 2022.11. 22.517543, 2022 | | 2022 |
Assessment of microstructural changes associated with levodopa-induced dyskinesia in hemiparkinsonian rodents M Bergamino, A Fuentes, D Marmion, I Sandoval, C Bishop, ... MOVEMENT DISORDERS 37, S111-S113, 2022 | | 2022 |