Understanding Coenzyme Q Y Wang, N Lilienfeldt, S Hekimi Physiological Reviews, 2024 | | 2024 |
Accessory subunit NDUFB4 participates in mitochondrial complex I supercomplex formation G Parmar, C Fong-McMaster, CA Pileggi, DA Patten, A Cuillerier, S Myers, ... Journal of Biological Chemistry 300 (2), 2024 | | 2024 |
Biallelic variants in COQ7 cause distal hereditary motor neuropathy with upper motor neuron signs AP Rebelo, PJ Tomaselli, J Medina, Y Wang, MF Dohrn, E Nyvltova, ... Brain 146 (10), 4191-4199, 2023 | 10 | 2023 |
Novel Homozygous Variant in COQ7 in Siblings With Hereditary Motor Neuropathy IC Smith, CA Pileggi, Y Wang, K Kernohan, T Hartley, HJ McMillan, ... Neurology: Genetics 9 (1), e200048, 2023 | 6 | 2023 |
Mitochondrial dysfunction, aging, and the mitochondrial unfolded protein response in Caenorhabditis elegans CM Haynes, S Hekimi Genetics 222 (4), iyac160, 2022 | 16 | 2022 |
Stimulation of RAS-dependent ROS signaling extends longevity by modulating a developmental program of global gene expression R Branicky, Y Wang, A Khaki, JL Liu, M Kramer-Drauberg, S Hekimi Science Advances 8 (48), eadc9851, 2022 | 5 | 2022 |
A novel COQ7 mutation causing primarily neuromuscular pathology and its treatment options Y Wang, E Gumus, S Hekimi Molecular Genetics and Metabolism Reports 31, 100877, 2022 | 21 | 2022 |
The CoQ biosynthetic di-iron carboxylate hydroxylase COQ7 is inhibited by in vivo metalation with manganese but remains function by metalation with cobalt Y Wang, S Hekimi MicroPublications biology, 2022 | 1 | 2022 |
The efficacy of coenzyme Q10 treatment in alleviating the symptoms of primary coenzyme Q10 deficiency: a systematic review Y Wang, S Hekimi Journal of Cellular and Molecular Medicine, 2022 | 18 | 2022 |
Minimal mitochondrial respiration is required to prevent cell death by inhibition of mTOR signaling in CoQ-deficient cells Y Wang, S Hekimi Cell Death Discovery 7 (1), 201, 2021 | 8 | 2021 |
Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis MP Rossmann, K Hoi, V Chan, BJ Abraham, S Yang, J Mullahoo, ... Science 372 (6543), 716-721, 2021 | 31 | 2021 |
Formulations for improving the delivery of hydrophobic agents S Hekimi, Y Wang | 1 | 2021 |
Micellization of coenzyme Q by the fungicide caspofungin allows for safe intravenous administration to reach extreme supraphysiological concentrations Y Wang, S Hekimi Redox Biology 36, 101680, 2020 | 20 | 2020 |
ROS regulation of RAS and vulva development in Caenorhabditis elegans M Kramer-Drauberg, JL Liu, D Desjardins, Y Wang, R Branicky, S Hekimi PLoS genetics 16 (6), e1008838, 2020 | 14 | 2020 |
SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans IE Krabbendam, B Honrath, B Dilberger, EF Iannetti, RS Branicky, ... Cell death & disease 11 (4), 263, 2020 | 42 | 2020 |
The complexity of making ubiquinone Y Wang, S Hekimi Trends in Endocrinology & Metabolism 30 (12), 929-943, 2019 | 56 | 2019 |
Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling Y Wang, R Branicky, A Noë, S Hekimi Journal of Cell Biology 217 (6), 1915-1928, 2018 | 1618 | 2018 |
Estimating the occurrence of primary ubiquinone deficiency by analysis of large-scale sequencing data BG Hughes, PM Harrison, S Hekimi Scientific reports 7 (1), 17744, 2017 | 36 | 2017 |
Pathogenicity of two COQ7 mutations and responses to 2,4‐dihydroxybenzoate bypass treatment Y Wang, C Smith, JS Parboosingh, A Khan, M Innes, S Hekimi Journal of cellular and molecular medicine 21 (10), 2329-2343, 2017 | 71 | 2017 |
Many possible maximum lifespan trajectories BG Hughes, S Hekimi Nature 546 (7660), E8-E9, 2017 | 45 | 2017 |