| Galectin-8N-Selective 4-Halophenylphthalazinone-Galactals Double π-Stack in a Unique Pocket S van Klaveren, M Hassan, M Håkansson, RE Johnsson, J Larsson, ... ACS Medicinal Chemistry Letters 15 (8), 1319-1324, 2024 | | 2024 |
| Discovery of the selective and orally available galectin-1 inhibitor GB1908 as a potential treatment for lung cancer FR Zetterberg, K Peterson, UJ Nilsson, K Andréasson Dahlgren, C Diehl, ... Journal of Medicinal Chemistry, 2024 | 1 | 2024 |
| Prospective de novo drug design with deep interactome learning K Atz, L Cotos, C Isert, M Håkansson, D Focht, M Hilleke, DF Nippa, M Iff, ... Nature Communications 15 (1), 3408, 2024 | 9 | 2024 |
| Discovery of selective and orally available galectin-1 inhibitors FR Zetterberg, C Diehl, M Håkansson, B Kahl-Knutson, H Leffler, ... Journal of Medicinal Chemistry 66 (24), 16980-16990, 2023 | 7 | 2023 |
| ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1 K Enell Smith, S Fritzell, A Nilsson, K Barchan, A Rosén, L Schultz, ... Cancer Immunology, Immunotherapy 72 (12), 4145-4159, 2023 | 3 | 2023 |
| Deep interactome learning for de novo drug design K Atz, LC Muñoz, C Isert, M Håkansson, D Focht, DF Nippa, M Hilleke, ... | 2 | 2023 |
| The bispecific tumor antigen-conditional 4–1BB x 5T4 agonist, ALG. APV-527, mediates strong T-Cell activation and potent antitumor activity in preclinical studies MH Nelson, S Fritzell, R Miller, D Werchau, D Van Citters, A Nilsson, ... Molecular Cancer Therapeutics 22 (1), 89-101, 2023 | 6 | 2023 |
| Crystal structure of DNA polymerase I from Thermus phage G20c J Ahlqvist, JA Linares-Pastén, A Jasilionis, M Welin, M Håkansson, ... Acta Crystallographica Section D: Structural Biology 78 (11), 1384-1398, 2022 | 3 | 2022 |
| Dusquetide modulates innate immune response through binding to p62 Y Zhang, CG Towers, UK Singh, J Liu, M Håkansson, DT Logan, O Donini, ... Structure 30 (8), 1055-1061. e7, 2022 | 2 | 2022 |
| Expression, purification and crystallization of a novel metagenome-derived salicylaldehyde dehydrogenase from Alpine soil SU Dandare, M Håkansson, LA Svensson, DJ Timson, CCR Allen Acta Crystallographica Section F: Structural Biology Communications 78 (4 …, 2022 | | 2022 |
| Crystal structure and initial characterization of a novel archaeal-like Holliday junction-resolving enzyme from Thermus thermophilus phage Tth15-6 J Ahlqvist, JA Linares-Pastén, M Håkansson, A Jasilionis, ... Acta Crystallographica Section D: Structural Biology 78 (2), 212-227, 2022 | 4 | 2022 |
| Structures of activin ligand traps using natural sets of type I and type II TGFβ receptors EJ Goebel, C Kattamuri, GR Gipson, L Krishnan, M Chavez, M Czepnik, ... IScience 25 (1), 2022 | 8 | 2022 |
| Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation M Hassan, S van Klaveren, M Håkansson, C Diehl, R Kovačič, ... European journal of medicinal chemistry 223, 113664, 2021 | 20 | 2021 |
| Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain M Hassan, F Baussière, S Guzelj, AP Sundin, M Håkansson, ... ACS medicinal chemistry letters 12 (11), 1745-1752, 2021 | 11 | 2021 |
| Going to extremes–a metagenomic journey into the dark matter of life A Aevarsson, AK Kaczorowska, BT Adalsteinsson, J Ahlqvist, ... FEMS microbiology letters 368 (12), fnab067, 2021 | 26 | 2021 |
| Expanding the Toolbox of R‐Selective Amine Transaminases by Identification and Characterization of New Members A Telzerow, J Paris, M Håkansson, J González‐Sabín, N Ríos‐Lombardía, ... ChemBioChem 22 (7), 1232-1242, 2021 | 15 | 2021 |
| Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology MJGW Ladds, G Popova, A Pastor-Fernández, S Kannan, ... Journal of Biological Chemistry 295 (52), 17935-17949, 2020 | 13 | 2020 |
| Current status and future opportunities for serial crystallography at MAX IV Laboratory A Shilova, H Lebrette, O Aurelius, J Nan, M Welin, R Kovacic, S Ghosh, ... Journal of Synchrotron Radiation 27 (5), 1095-1102, 2020 | 13 | 2020 |
| Molecular characterization of a novel lytic enzyme LysC from Clostridium intestinale URNW and its antibacterial activity mediated by positively charged N-terminal extension M Plotka, M Szadkowska, M Håkansson, R Kovačič, S Al-Karadaghi, ... International journal of molecular sciences 21 (14), 4894, 2020 | 19 | 2020 |
| N‐locking stabilization of covalent helical peptides: Application to Bfl‐1 antagonists C Baggio, P Udompholkul, L Gambini, J Jossart, AF Salem, M Håkansson, ... Chemical biology & drug design 95 (4), 412-426, 2020 | 8 | 2020 |
