关注
Junxian Lim
Junxian Lim
University of Queensland, Institute for Molecular Bioscience
在 uq.edu.au 的电子邮件经过验证 - 首页
标题
引用次数
年份
Protease-activated receptor 2: a promising therapeutic target for women's cancers
H Shah, DP Fairlie, J Lim
Journal of Pharmacology and Experimental Therapeutics, 2024
2024
Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cells
H Shah, TA Hill, J Lim, DP Fairlie
Journal of Cell Communication and Signaling 17 (4), 1293-1307, 2023
12023
Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: limacodidae)
MH Goudarzi, DA Eagles, J Lim, KA Biggs, AC Kotze, AP Ruffell, ...
Biochemical Pharmacology 213, 115598, 2023
22023
Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages
KC Wu, ND Condon, TA Hill, RC Reid, DP Fairlie, J Lim
Journal of Innate Immunity 15 (1), 468-484, 2023
32023
Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles
P Wang, TA Hill, J Mitchell, RL Fitzsimmons, W Xu, Z Loh, JY Suen, J Lim, ...
Journal of Medicinal Chemistry 65 (17), 11759-11775, 2022
42022
Tuning electrostatic and hydrophobic surfaces of aromatic rings to enhance membrane association and cell uptake of peptides
AD de Araujo, HN Hoang, J Lim, JYW Mak, DP Fairlie
Angewandte Chemie 134 (29), e202203995, 2022
172022
Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation
E Sinniah, Z Wu, S Shen, M Naval-Sanchez, X Chen, J Lim, A Helfer, ...
Cell Reports 39 (7), 2022
12022
The histone deacetylase Hdac7 supports LPS-inducible glycolysis and Il-1β production in murine macrophages via distinct mechanisms
D Ramnath, K Das Gupta, Y Wang, R Abrol, JEB Curson, J Lim, RC Reid, ...
Journal of Leukocyte Biology 111 (2), 327-336, 2022
92022
Chemical Biology
AD de Araujo, J Lim, KC Wu, HN Hoang, HT Nguyen, DP Fairlie
2022
Helical structure in cyclic peptides: effect of N-methyl amides versus esters
C Wu, HN Hoang, TA Hill, J Lim, WM Kok, K Akondi, L Liu, DP Fairlie
Chemical Communications 58 (89), 12475-12478, 2022
32022
Landscaping macrocyclic peptides: stapling hDM2-binding peptides for helicity, protein affinity, proteolytic stability and cell uptake
AD de Araujo, J Lim, KC Wu, HN Hoang, HT Nguyen, DP Fairlie
RSC Chemical Biology 3 (7), 895-904, 2022
132022
HDAC7 inhibition by phenacetyl and phenylbenzoyl hydroxamates
JYW Mak, KC Wu, PK Gupta, S Barbero, MG McLaughlin, AJ Lucke, J Tng, ...
Journal of Medicinal Chemistry 64 (4), 2186-2204, 2021
152021
PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR
Y Jiang, J Lim, KC Wu, W Xu, JY Suen, DP Fairlie
British Journal of Pharmacology 178 (4), 913-932, 2021
252021
Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition
AJ Kennedy, L Sundström, S Geschwindner, EKY Poon, Y Jiang, R Chen, ...
Communications biology 3 (1), 782, 2020
272020
Achiral derivatives of hydroxamate AR-42 potently inhibit HDAC1 and cancer cell proliferation
A Lucke, KC Wu, J Tng, R Reid, J Lim, W Xu, D Fairlie
American Chemical Society SciMeetings 1 (2), 2020
2020
Achiral derivatives of hydroxamate AR-42 potently inhibit class I HDAC enzymes and cancer cell proliferation
J Tng, J Lim, KC Wu, AJ Lucke, W Xu, RC Reid, DP Fairlie
Journal of medicinal chemistry 63 (11), 5956-5971, 2020
212020
Potent thiophene antagonists of human complement C3a receptor with anti-inflammatory activity
JA Rowley, RC Reid, EKY Poon, KC Wu, J Lim, RJ Lohman, JK Hamidon, ...
Journal of Medicinal Chemistry 63 (2), 529-541, 2020
202020
Heterocycles for switching GPCR ligand conformation and activity
D Fairlie, R Reid, J Rowley, KC Wu, MK Yau, J Lim, A Iyer
Abstracts of Papers of the American Chemical Society 257, 2019
2019
Chemical synthesis and applications of a novel fluorescent probe for human complement C3a receptor
C Wu, A de Araujo, KC Wu, R Reid, T Durek, J Lim, D Fairlie
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Bicyclic helical peptides as dual inhibitors selective for Bcl2A1 and Mcl-1 proteins
A D. de Araujo, J Lim, KC Wu, Y Xiang, AC Good, R Skerlj, DP Fairlie
Journal of medicinal chemistry 61 (7), 2962-2972, 2018
462018
系统目前无法执行此操作,请稍后再试。
文章 1–20