Chlorination of epithelial tight junction proteins by neutrophil myeloperoxidase promotes barrier dysfunction and mucosal inflammation IM Cartwright, L Zhou, SD Koch, N Welch, D Zakharov, R Callahan, ... JCI Insight 9 (14), 2024 | | 2024 |
Sa1202 PHOSPHOCREATINE SUPPLEMENTATION INDUCES PROTECTIVE EFFECT ON MURINE COLITIS AND INTESTINAL EPITHELIAL CELL FUNCTION G Bhagavatula, R Neuhart, C Worledge, JS Lee, I Cartwright, SP Colgan, ... Gastroenterology 166 (5), S-382, 2024 | | 2024 |
Abstract 1503 Microbiota-derived butyrate is an endogenous HIF prolyl hydroxylase inhibitor M Henen, R Wang, J Lee, S Colgan, B Vogeli Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Allopurinol Disrupts Purine Metabolism to Increase Damage in Experimental Colitis CS Worledge, RE Kostelecky, L Zhou, G Bhagavatula, SP Colgan, JS Lee Cells 13 (5), 373, 2024 | | 2024 |
Microbiota-dependent indole production stimulates the development of collagen-induced arthritis in mice BJ Seymour, B Trent, BE Allen, AJ Berlinberg, J Tangchittsumran, ... The Journal of Clinical Investigation 134 (4), 2024 | 6 | 2024 |
PROTEOLYSIS TARGETING CHIMERAS (PROTACS) AS ATTRACTIVE THERAPEUTICS IN IBD THROUGH THE REGULATION OF HYPOXIA-INDUCIBLE FACTORS A Ornelas, J Countess, N Welch, I Cartwright, S Colgan Gastroenterology 166 (3), S83-S84, 2024 | | 2024 |
Epithelial heme oxygenase-1 enhances colonic tumorigenesis by inhibiting ferroptosis RC Callahan, G Bhagavatula, J Curry, AW Staley, REM Schaefer, ... bioRxiv, 2024.03. 06.583112, 2024 | | 2024 |
Mimicry of microbially-derived butyrate reveals templates for potent intestinal epithelial HIF stabilizers A Ornelas, N Welch, JA Countess, L Zhou, RX Wang, AS Dowdell, ... Gut Microbes 15 (2), 2267706, 2023 | 1 | 2023 |
Fundamental role for the creatine kinase pathway in protection from murine colitis CHT Hall, JM Lanis, AS Dowdell, EM Murphy, G Bhagavatula, ... Mucosal Immunology 16 (6), 817-825, 2023 | 2 | 2023 |
Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice KM Alula, AS Dowdell, B LeBere, JS Lee, CL Levens, KA Kuhn, ... Microbiome 11 (1), 256, 2023 | 6 | 2023 |
Microbiota-dependent indole production is required for the development of collagen-induced arthritis BJ Seymour, B Trent, B Allen, AJ Berlinberg, J Tangchittsumran, ... bioRxiv, 2023 | 1 | 2023 |
OVEREXPRESSION OF TNFalpha CONTRIBUTES TO INCREASED HEPATIC INFLAMMATION AND CHOLANGIOCYTE PROLIFERATION IN MICE CT Shearn, A Anderson, M Devereaux, SD Koch, DJ Orlicky, C Steiner, ... HEPATOLOGY 78, S1790-S1790, 2023 | | 2023 |
Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models D Feng, X Xiang, Y Guan, A Guillot, H Lu, C Chang, Y He, H Wang, H Pan, ... The Journal of Clinical Investigation 133 (15), 2023 | 19 | 2023 |
The TNFΔARE mouse as a model of intestinal fibrosis CA Steiner, SD Koch, T Evanoff, N Welch, R Kostelecky, R Callahan, ... The American Journal of Pathology 193 (8), 1013-1028, 2023 | 2 | 2023 |
Epithelial heme oxygenase-1 promotes colitis associated tumorigenesis through regulation of tumor epithelial differentiation and survival R Callahan, J Onyiah, G Bhagavatula, R Schaefer, A Staley, E Murphy, ... Physiology 38 (S1), 5796045, 2023 | | 2023 |
Bacterial catabolism of tryptophan to indole is required to induce collagen induced arthritis via the IL23/Th17 axis B Seymour, B Allen, B Trent, A Berlinberg, W Jubair, S Colgan, K Kuhn The Journal of Immunology 210 (1_Supplement), 165.03-165.03, 2023 | | 2023 |
Tu1221 LOSS OF CREATINE KINASE RESULTS IN A DEFECTIVE INTESTINAL EPITHELIAL BARRIER, WHICH IS RESCUED BY PHOSPHOCREATINE SUPPLEMENTATION G Bhagavatula, JS Lee, I Cartwright, SP Colgan, C Hall Gastroenterology 164 (6), S-998, 2023 | | 2023 |
Synaptopodin is necessary for Shigella flexneri intercellular spread JM Vickery, JD Toperzer, JE Raab, LL Lenz, SP Colgan, BC Russo bioRxiv, 2023.04. 25.537990, 2023 | | 2023 |
Butyrate ameliorates Paneth cell defects, total inflammation, and epithelial cell apoptosis during mitochondrial dysfunction driven by Prohibitin 1-deficiency K Alula, A Dowdell, J Lee, S Colgan, A Theiss Gastroenterology 164 (4), S63, 2023 | | 2023 |
STRUCTURAL MODIFICATIONS OF BUTYRATE REVEAL TEMPLATES FOR INTESTINAL EPITHELIAL HIF STABILIZERS A Ornelas, R Wang, J Countess, S Colgan Gastroenterology 164 (4), S62, 2023 | | 2023 |