Hydroxytyrosol Linoleoyl Ether Ameliorates Metabolic-Associated Fatty Liver Disease Symptoms in Obese Zucker Rats R Tovar, M de Ceglia, M Rodríguez-Pozo, A Vargas, A Gavito, J Suárez, ... ACS Pharmacology & Translational Science 7 (5), 1571-1583, 2024 | | 2024 |
基于 D-Pinitol 的治疗的新见解: tau 过度磷酸化和胰岛素抵抗之间的联系 D Medina-Vera, AJ López-Gambero, JA Navarro, C Sanjuan, E Baixeras, ... 中国神经再生研究 (英文版) 19 (2), 289, 2024 | | 2024 |
Novel insights into D-Pinitol based therapies: a link between tau hyperphosphorylation and insulin resistance D Medina-Vera, AJ López-Gambero, JA Navarro, C Sanjuan, E Baixeras, ... Neural Regeneration Research 19 (2), 289-295, 2024 | | 2024 |
Administration of Linoleoylethanolamide Reduced Weight Gain, Dyslipidemia, and Inflammation Associated with High-Fat-Diet-Induced Obesity R Tovar, M de Ceglia, M Ubaldi, M Rodríguez-Pozo, L Soverchia, C Cifani, ... Nutrients 15 (20), 4448, 2023 | 1 | 2023 |
Transcending the amyloid-beta dominance paradigm in Alzheimer's disease: An exploration of behavioural, metabolic, and gut microbiota phenotypes in 5xFAD mice D Medina-Vera, EN Zambrana-Infantes, AJ Lopez-Gambero, ... Neurobiology of disease 187, 106295, 2023 | 4 | 2023 |
CONTINUED TREATMENT OF D-PINITOL AMELIORATES COGNITIVE SPATIAL FLEXIBILITY OF ALZHEIMER’S DISEASE 5XFAD TRANSGENIC MICE D Medina-Vera, C Rosell-Valle, AJ López-Gambero, JA Navarro, ... IBRO Neuroscience Reports 15, S449-S450, 2023 | | 2023 |
Insulin signaling and neurological disorders: investigating the therapeutic potential of D-pinitol in Alzheimer's disease and tauopathies D Medina-Vera, AJ López-Gambero, C Sanjuan, E Baixeras, J Decara, ... Neuroscience Applied 2, 103779, 2023 | | 2023 |
Pharmacokinetics and endocrine effects of an oral dose of D-Pinitol in human fasting healthy volunteers JA Navarro, C Díaz, J Decara, D Medina-Vera, AJ Lopez-Gambero, ... Nutrients 14 (19), 4094, 2022 | 7 | 2022 |
d‐Pinitol promotes tau dephosphorylation through a cyclin‐dependent kinase 5 regulation mechanism: A new potential approach for tauopathies? D Medina‐Vera, JA Navarro, P Rivera, C Rosell‐Valle, A Gutiérrez‐Adán, ... British journal of pharmacology 179 (19), 4655-4672, 2022 | 14 | 2022 |
Gene dosage determines the behavioural phenotype in the 5xFAD mouse model of Alzheimer’s disease: analysis of the contribution of brain insulin signalling and gut microbiota D Medina-Vera, EN Zambrana-Infantes, AJ López-Gambero, ... | | 2022 |
Endocrine and metabolic impact of oral ingestion of a carob-pod-derived natural-syrup-containing d-pinitol: potential use as a novel sweetener in diabetes JA Navarro, J Decara, D Medina-Vera, R Tovar, AJ Lopez-Gambero, ... Pharmaceutics 14 (8), 1594, 2022 | 3 | 2022 |
Discovery of V-0219: a small-molecule positive allosteric modulator of the glucagon-like peptide-1 receptor toward oral treatment for “diabesity” JM Decara, H Vázquez-Villa, J Brea, M Alonso, RK Srivastava, L Orio, ... Journal of medicinal chemistry 65 (7), 5449-5461, 2022 | 8 | 2022 |
Palmitoleoylethanolamide is an efficient anti-obesity endogenous compound: comparison with oleylethanolamide in diet-induced obesity R Tovar, AL Gavito, A Vargas, L Soverchia, L Hernandez-Folgado, ... Nutrients 13 (8), 2589, 2021 | 17 | 2021 |
Activation of PI3K/Akt signaling pathway in rat hypothalamus induced by an acute oral administration of d-pinitol D Medina-Vera, JA Navarro, R Tovar, C Rosell-Valle, A Gutiérrez-Adan, ... Nutrients 13 (7), 2268, 2021 | 14 | 2021 |
D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome E Pericuesta Camacho, R Laguna-Barraza, P Ramos Ibeas, ... Departamento de Reproducción Animal, 2020 | | 2020 |
D-chiro-inositol treatment affects oocyte and embryo quality and improves glucose intolerance in both aged mice and mouse models of polycystic ovarian syndrome E Pericuesta, R Laguna-Barraza, P Ramos-Ibeas, JL Gutierrez-Arroyo, ... International Journal of Molecular Sciences 21 (17), 6049, 2020 | 12 | 2020 |
D-Pinitol from Ceratonia siliqua Is an Orally Active Natural Inositol That Reduces Pancreas Insulin Secretion and Increases Circulating Ghrelin Levels in Wistar Rats JA Navarro, J Decara, D Medina-Vera, R Tovar, J Suarez, J Pavón, ... Nutrients 12 (7), 2030, 2020 | 25 | 2020 |
Peroxisome proliferator-activated receptors: Experimental targeting for the treatment of inflammatory bowel diseases J Decara, P Rivera, AJ López-Gambero, A Serrano, FJ Pavón, E Baixeras, ... Frontiers in pharmacology 11, 730, 2020 | 111 | 2020 |
Cocaine-induced changes in CX3CL1 and inflammatory signaling pathways in the hippocampus: Association with IL1β J Montesinos, E Castilla-Ortega, L Sánchez-Marín, S Montagud-Romero, ... Neuropharmacology 162, 107840, 2020 | 20 | 2020 |
The adiponectin promoter activator NP-1 induces high levels of circulating TNFα and weight loss in obese (fa/fa) Zucker rats J Decara, A Serrano, FJ Pavón, P Rivera, R Arco, A Gavito, A Vargas, ... Scientific reports 8 (1), 9858, 2018 | 12 | 2018 |