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Christopher Desjardins
Christopher Desjardins
Aera Therapeutics
在 aeratx.com 的电子邮件经过验证
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引用次数
年份
Use of immunotherapy and microbiome modulation to treat cancer
E HALVORSEN, C Desjardins, K BARDHAN, SD PANDIAN
US Patent App. 18/546,922, 2024
2024
Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pangenome hybrid selection
MG Young, TJ Straub, CJ Worby, HC Metsky, A Gnirke, RA Bronson, ...
bioRxiv, 2024
2024
607 MCGRAW trial: evaluation of the safety and efficacy of an oral microbiome intervention (SER-401) in combination with nivolumab in first line metastatic melanoma patients
IG Oliva, O Hamid, P Ott, G Boland, R Sullivan, K Grossmann, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
62022
110: IMPACT OF SER-109, AN INVESTIGATIONAL MICROBIOME THERAPEUTIC, ON STOOL FATTY ACID METABOLITES IN A PHASE 3 RANDOMIZED TRIAL (ECOSPOR III) FOR TREATMENT OF RECURRENT …
JA Bryant, M Vulic, C Desjardins, CB Ford, KD Litcofsky, JR Wortman, ...
Gastroenterology 162 (7), S-21, 2022
22022
Engraftment of investigational microbiome therapeutic SER-109 is durable through 24 weeks in a randomized trial (ECOSPOR III) for the treatment of recurrent Clostridioides …
C Desjardins, JA Bryant, E Walsh, CB Ford, KD Litcofsky, JR Wortman, ...
GASTROENTEROLOGY 162 (7), S651-S651, 2022
12022
Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women
CJ Worby, HL Schreiber IV, TJ Straub, LR van Dijk, RA Bronson, ...
Nature microbiology 7 (5), 630-639, 2022
892022
Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections
TJ Straub, WC Chou, AL Manson, HL Schreiber, BJ Walker, ...
BMC microbiology 21, 1-17, 2021
242021
Treatment of a cancer by microbiome modulation
J Wortman, D Liyang, C Desjardins, G Marnellos, H Matthew, J Wargo, ...
US Patent App. 15/733,682, 2021
22021
SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial
BH McGovern, CB Ford, MR Henn, DS Pardi, S Khanna, EL Hohmann, ...
Clinical Infectious Diseases 72 (12), 2132-2140, 2021
1312021
Assessment of cancer-specific microbiome signature of response to immune checkpoint inhibitors.
M Sarfaty, CA Desjardins, P Giardina, K Bardhan, S Pandian, K Halley, ...
Journal of Clinical Oncology 39 (15_suppl), 2574-2574, 2021
22021
Leveraging gut microbiota networks to impact tumor immunotherapy.
J Sceneay, S Srinivasan, K Halley, M Bist, K Cieciuch, G Marnellos, ...
CANCER IMMUNOLOGY RESEARCH 8 (4), 26-26, 2020
2020
Abstract PR01: Leveraging gut microbiota networks to impact tumor immunotherapy
J Sceneay, S Srinivasan, K Halley, M Bist, K Cieciuch, G Marnellos, ...
Cancer Immunology Research 8 (4_Supplement), PR01-PR01, 2020
2020
Landscape of gene expression variation of natural isolates of Cryptococcus neoformans in response to biologically relevant stresses
CH Yu, Y Chen, CA Desjardins, JL Tenor, DL Toffaletti, C Giamberardino, ...
Microbial genomics 6 (1), e000319, 2020
292020
Extensive global movement of multidrug-resistant M. tuberculosis strains revealed by whole-genome analysis
KA Cohen, AL Manson, T Abeel, CA Desjardins, SB Chapman, S Hoffner, ...
Thorax 74 (9), 882-889, 2019
292019
Deciphering drug resistance in Mycobacterium tuberculosis using whole-genome sequencing: progress, promise, and challenges
KA Cohen, AL Manson, CA Desjardins, T Abeel, AM Earl
Genome medicine 11 (1), 45, 2019
1362019
623–Ser-287, an investigational microbiome therapeutic, induces widespread transcriptional changes related to clinical remission in a placebo-controlled, double-blind …
L Diao, MC Nnamani, E OBrien, C Desjardins, A Martinez, S Simmons, ...
Gastroenterology 156 (6), S-130, 2019
52019
Abstract B063: Leveraging gut microbiota networks to impact tumor immunotherapy
L Jayaraman, J Sceneay, S Srinivasan, K Halley, M Bist, K Cieciuch, ...
Cancer Immunology Research 7 (2_Supplement), B063-B063, 2019
32019
Antagonistic paralogs control a switch between growth and pathogen resistance in C. elegans
KC Reddy, T Dror, RS Underwood, GA Osman, CR Elder, CA Desjardins, ...
PLoS pathogens 15 (1), e1007528, 2019
742019
621. Treatment of Recurrent Clostridium difficile Infection with SER-109 Increases the Concentration of Secondary Bile Acids in a Dose-Dependent Manner
M Henn, C Ford, E O’Brien, J Wortman, L Diao, C Desjardins, ...
Open Forum Infectious Diseases 5 (suppl_1), S226-S227, 2018
22018
SynerClust: a highly scalable, synteny-aware orthologue clustering tool
CH Georgescu, AL Manson, AD Griggs, CA Desjardins, A Pironti, ...
Microbial genomics 4 (11), e000231, 2018
182018
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