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Richard Upton
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Su1810 USING A PHARMACOKINETIC SIMULATION MODEL TO DETERMINE THE OPTIMAL INFLIXIMAB INTENSIFICATION STRATEGY IN INFLAMMATORY BOWEL DISEASE
A Srinivasan, R Upton
Gastroenterology 166 (5), S-824, 2024
2024
“Getting the Dose Right”—Revisiting the Topic With Focus on Biologic Agents
DR Mould, RN Upton
Clinical Pharmacology & Therapeutics, 2024
2024
Application of a Precision‐Dosing Model to a Real‐World Cohort of Patients on Infliximab Maintenance Therapy: Drug Usage and Cost Analysis
AL Nguyen, PR Gibson, RN Upton, DR Mould, MP Sparrow
The Journal of Clinical Pharmacology 64 (4), 399-409, 2024
2024
Combining the potential of 3D printed buccal films and nanostructured lipid carriers for personalised cannabidiol delivery
S Abdella, S Kim, F Afinjuomo, Y Song, R Upton, S Garg
Drug Delivery and Translational Research 14 (4), 984-1004, 2024
2024
Using a pharmacokinetic simulation model to determine the optimal infliximab intensification strategy to address loss of response in inflammatory bowel disease
A Srinivasan, R Upton
JOURNAL OF CROHNS & COLITIS 18, I1290-+, 2024
2024
P684 Using a pharmacokinetic simulation model to determine the optimal infliximab intensification strategy to address loss of response in inflammatory bowel disease
A Srinivasan, R Upton
Journal of Crohn's and Colitis 18 (Supplement_1), i1300-i1303, 2024
2024
Dynamic exposure and body burden models for per-and polyfluoroalkyl substances (PFAS) enable management of food safety risks in cattle
AT Mikkonen, J Martin, RN Upton, JL Moenning, J Numata, MP Taylor, ...
Environment International 180, 108218, 2023
2023
Harnessing the Synergistic Potential of 3D Printed Buccal Films and Nanostructured Lipid Carriers (NLCs) For Personalised Cannabidiol Delivery
S Abdella, S Kim, F Afinjuomo, Y Song, R Upton, S Garg
2023
Spatio-temporal trends in livestock exposure to per-and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures
AT Mikkonen, J Martin, RN Upton, AO Barker, CM Brumley, MP Taylor, ...
Environmental Research 225, 115518, 2023
62023
3D printed bilayer mucoadhesive buccal film of estradiol: Impact of design on film properties, release kinetics and predicted in vivo performance
S Abdella, F Afinjuomo, Y Song, R Upton, S Garg
International Journal of Pharmaceutics 628, 122324, 2022
122022
Subtherapeutic dosing occurs in one-half of patients on infliximab maintenance therapy for inflammatory bowel disease
A Nguyen, P Gibson, D Mould, R Upton, M Sparrow
Zeitschrift für Gastroenterologie 60 (08), KA527, 2022
2022
SUBTHERAPEUTIC DOSING OCCURS IN ONE-THIRD OF PATIENTS ON INFLIXIMAB MAINTENANCE THERAPY FOR INFLAMMATORY BOWEL DISEASE
A Nguyen, PR Gibson, DR Mould, RN Upton, M Sparrow
GASTROENTEROLOGY 162 (7), S1096-S1097, 2022
2022
EP1309: SUBTHERAPEUTIC DOSING OCCURS IN ONE-THIRD OF PATIENTS ON INFLIXIMAB MAINTENANCE THERAPY FOR INFLAMMATORY BOWEL DISEASE
A Nguyen, PR Gibson, DR Mould, RN Upton, M Sparrow
Gastroenterology 162 (7), S-1096-S-1097, 2022
2022
Population Pharmacokinetic Model for Tramadol and O-desmethyltramadol in Older Patients
AA Al-Qurain, RN Upton, R Tadros, MS Roberts, MD Wiese
European Journal of Drug Metabolism and Pharmacokinetics 47 (3), 387-402, 2022
12022
Mucoadhesive buccal film of estradiol for hormonal replacement therapy: development and in-vivo performance prediction
S Abdella, F Afinjuomo, Y Song, R Upton, S Garg
Pharmaceutics 14 (3), 542, 2022
152022
3D Printing of thermo-sensitive drugs
S Abdella, SH Youssef, F Afinjuomo, Y Song, P Fouladian, R Upton, ...
Pharmaceutics 13 (9), 1524, 2021
312021
Population pharmacokinetic model of subcutaneous fentanyl in older acute care patients
AA Al-Qurain, R Upton, DB Williams, L Mackenzie, C Phillips, PT Russell, ...
European Journal of Clinical Pharmacology 77, 1357-1368, 2021
22021
Physiologically Based Models: Techniques and Applications to Drug Delivery
RN Upton, AM Hopkins, AY Abuhelwa, JH Hughes, DJR Foster
Drug Delivery Approaches: Perspectives from Pharmacokinetics and …, 2021
2021
Pharmacokinetic Modelling of Human Recombinant Protein, p75ECD-Fc: A Novel Therapeutic Approach for Treatment of Alzheimer’s Disease, in Serum and Tissue of Sprague Dawley Rats
S Kelliny, L Bobrovskaya, XF Zhou, R Upton
European Journal of Drug Metabolism and Pharmacokinetics 46, 235-248, 2021
12021
3D Printing of Thermo-Sensitive Drugs. Pharmaceutics 2021, 13, 1524
S Abdella, SH Youssef, F Afinjuomo, Y Song, P Fouladian, R Upton, ...
s Note: MDPI stays neu-tral with regard to jurisdictional claims in …, 2021
12021
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