Tension activation of mechanosensitive two-pore domain K+ channels TRAAK, TREK-1, and TREK-2 B Sorum, T Docter, V Panico, RA Rietmeijer, SG Brohawn Nature communications 15 (1), 3142, 2024 | | 2024 |
Structural basis for assembly and lipid-mediated gating of LRRC8A: C volume-regulated anion channels DM Kern, J Bleier, S Mukherjee, JM Hill, AA Kossiakoff, EY Isacoff, ... Nature Structural & Molecular Biology 30 (6), 841-852, 2023 | 18 | 2023 |
Pressure and ultrasound activate mechanosensitive TRAAK K+ channels through increased membrane tension B Sorum, T Docter, V Panico, RA Rietmeijer, SG Brohawn bioRxiv, 2023 | 3 | 2023 |
Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A CM Hoel, L Zhang, SG Brohawn Elife 11, e81704, 2022 | 10 | 2022 |
Structure of SARS-CoV-2 M protein in lipid nanodiscs KA Dolan, M Dutta, DM Kern, A Kotecha, GA Voth, SG Brohawn Elife 11, e81702, 2022 | 47 | 2022 |
Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs K Tucker, S Sridharan, H Adesnik, SG Brohawn Nature communications 13 (1), 4842, 2022 | 24 | 2022 |
High-performance microbial opsins for spatially and temporally precise perturbations of large neuronal networks S Sridharan, MA Gajowa, MB Ogando, UK Jagadisan, L Abdeladim, ... Neuron 110 (7), 1139-1155. e6, 2022 | 67 | 2022 |
Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes SK Gunasekar, L Xie, A Kumar, J Hong, PR Chheda, C Kang, DM Kern, ... Nature communications 13 (1), 784, 2022 | 21 | 2022 |
Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca2+-dependent switch from intra- to intermembrane dimerization B Li, CM Hoel, SG Brohawn Nature communications 12 (1), 6913, 2021 | 16 | 2021 |
Physical basis for distinct basal and mechanically gated activity of the human K+ channel TRAAK RA Rietmeijer, B Sorum, B Li, SG Brohawn Neuron 109 (18), 2902-2913. e4, 2021 | 11 | 2021 |
Author Correction: Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs DM Kern, B Sorum, SS Mali, CM Hoel, S Sridharan, JP Remis, DB Toso, ... Nature structural & molecular biology 28 (8), 702-702, 2021 | 5 | 2021 |
Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs DM Kern, B Sorum, SS Mali, CM Hoel, S Sridharan, JP Remis, DB Toso, ... Nature structural & molecular biology 28 (7), 573-582, 2021 | 206 | 2021 |
10.3 Bacterial preparation of anti-GFP nanobody DM Kern, SG Brohawn Ion Channels: Channel Production and Optical Methods, 231, 2021 | | 2021 |
Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex JY Wang, CM Hoel, B Al-Shayeb, JF Banfield, SG Brohawn, JA Doudna Nature communications 12 (1), 2571, 2021 | 12 | 2021 |
Small molecule SWELL1-LRRC8 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes SK Gunasekar, L Xie, PR Chheda, C Kang, DM Kern, C My-Ta, A Kumar, ... bioRxiv, 2021.02. 28.432901, 2021 | 1 | 2021 |
Ultrasound activates mechanosensitive TRAAK K+ channels through the lipid membrane B Sorum, RA Rietmeijer, K Gopakumar, H Adesnik, SG Brohawn Proceedings of the National Academy of Sciences 118 (6), e2006980118, 2021 | 90 | 2021 |
SARS-CoV-2 3a expression, purification, and reconstitution into lipid nanodiscs DM Kern, SG Brohawn Methods in Enzymology 653, 207-235, 2021 | 1 | 2021 |
Ultrasound activates mechanosensitive TRAAK K+ channels directly through the lipid membrane B Sorum, RA Rietmeijer, K Gopakumar, H Adesnik, SG Brohawn bioRxiv, 2020.10. 24.349738, 2020 | 1 | 2020 |
Structural coordination between active sites of a Cas6-reverse transcriptase-Cas1—Cas2 CRISPR integrase complex JY Wang, CM Hoel, B Al-Shayeb, JF Banfield, SG Brohawn, JA Doudna bioRxiv, 2020.10. 18.344481, 2020 | 1 | 2020 |
Structural basis for pH gating of the two-pore domain K+ channel TASK2 B Li, RA Rietmeijer, SG Brohawn Nature 586 (7829), 457-462, 2020 | 57 | 2020 |