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Richard J. A. Goodwin
Richard J. A. Goodwin
在 astrazeneca.com 的电子邮件经过验证
标题
引用次数
年份
Multimodal Mass Spectrometry Imaging of an Osteosarcoma Multicellular Tumour Spheroid Model to Investigate Drug-Induced Response
SM Pearce, NA Cross, DP Smith, MR Clench, LE Flint, G Hamm, ...
Metabolites 14 (6), 315, 2024
2024
Morphological and molecular preservation through universal preparation of fresh-frozen tissue samples for multimodal imaging workflows
A Dannhorn, E Kazanc, L Flint, F Guo, A Carter, AR Hall, SA Jones, ...
Nature Protocols, 1-27, 2024
2024
Functional mouse hepatocytes derived from interspecies chimeric livers effectively mitigate chronic liver fibrosis
C Huang, H Jiang, J Dong, L Jiang, J Li, J Xu, T Cui, L Wang, X Li, G Feng, ...
Stem Cell Reports, 2024
2024
Accelerating drug development using spatial multi-omics
RJA Goodwin, SJ Platz, JS Reis-Filho, ST Barry
Cancer Discovery 14 (4), 620-624, 2024
12024
Probing intratumoral metabolic compartmentalisation in fumarate hydratase-deficient renal cancer using clinical hyperpolarised 13C-MRI and mass spectrometry imaging
I Horvat-Menih, R Casey, J Denholm, G Hamm, H Hulme, J Gallon, ...
medRxiv, 2024.05. 06.24306817, 2024
2024
Spatial mapping of dextran sodium sulphate-induced intestinal inflammation and its systemic effects
L Adams, O Rasid, H Hulme, T Quon, R Burchmore, S Milling, R Goodwin, ...
bioRxiv, 2024.04. 26.591292, 2024
2024
Microbiome-derived metabolite effects on intestinal barrier integrity and immune cell response to infection
L Adams, X Li, R Burchmore, R Goodwin, DM Wall
bioRxiv, 2024.02. 06.579072, 2024
2024
Large-Scale Evaluation of Spatial Metabolomics Protocols and Technologies
V Saharuka, LM Vieira, L Stuart, M Ekelöf, MR Molenaar, A Bailoni, ...
bioRxiv, 2024.01. 29.577354, 2024
12024
Imaging tumor lactate is feasible for identifying intermediate-risk prostate cancer patients with postsurgical biochemical recurrence
N Sushentsev, G Hamm, J Richings, MA McLean, IH Menih, V Ayyappan, ...
Proceedings of the National Academy of Sciences 120 (49), e2312261120, 2023
32023
Vitamin B5 supports MYC oncogenic metabolism and tumor progression in breast cancer
P Kreuzaler, P Inglese, A Ghanate, E Gjelaj, V Wu, Y Panina, ...
Nature metabolism 5 (11), 1870-1886, 2023
112023
Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models
L Hopcroft, EM Wigmore, SC Williamson, S Ros, C Eberlein, JI Moss, ...
NPJ Breast Cancer 9 (1), 64, 2023
72023
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
J Vande Voorde, RT Steven, AK Najumudeen, CA Ford, A Dexter, ...
Nature metabolism 5 (8), 1303-1318, 2023
112023
Tissue Mass Spectrometry: How Solid Is Our Future?
D Unsihuay, WS Phipps, AG Paulovich, JR Chapman, A Ducret, ...
Clinical Chemistry 69 (7), 676-683, 2023
2023
Targeted desorption electrospray ionization mass spectrometry imaging for drug distribution, toxicity, and tissue classification studies
A Dannhorn, ML Doria, J McKenzie, P Inglese, JG Swales, G Hamm, ...
Metabolites 13 (3), 377, 2023
72023
Targeting succinate metabolism to decrease brain injury upon mechanical thrombectomy treatment of ischemic stroke
A Mottahedin, HA Prag, A Dannhorn, R Mair, C Schmidt, M Yang, ...
Redox Biology 59, 102600, 2023
142023
Metabolic imaging across scales reveals distinct prostate cancer phenotypes
N Sushentsev, G Hamm, L Flint, D Birtles, A Zakirov, J Richings, S Ling, ...
medRxiv, 2023.09. 29.23296228, 2023
2023
Author Correction: Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models
L Hopcroft, EM Wigmore, SC Williamson, S Ros, C Eberlein, JI Moss, ...
NPJ breast cancer 9, 2023
2023
Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma
V Graziano, A Dannhorn, H Hulme, K Williamson, H Buckley, SA Karim, ...
Journal for ImmunoTherapy of Cancer 11 (8), 2023
32023
Ischemia-selective protection against cardiac ischemia/reperfusion injury by malonate
H Prag, D Aksentijevic, A Dannhorn, A Giles, J Mulvey, O Sauchanka, ...
Journal of Molecular and Cellular Cardiology 173, S5, 2022
12022
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer
SJ Adua, A Arnal-Estapé, M Zhao, B Qi, ZZ Liu, C Kravitz, H Hulme, ...
Nature Communications 13 (1), 7690, 2022
102022
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