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Stephen Sligar
Stephen Sligar
在 illinois.edu 的电子邮件经过验证 - 首页
标题
引用次数
年份
Optical annealing of peroxo-ferric intermediates in CYP17A1 and product formation.
IG Denisov, YV Grinkova, SG Sligar
Journal of Inorganic Biochemistry, 112701, 2024
2024
Nanodiscs for the study of membrane proteins
IG Denisov, SG Sligar
Current Opinion in Structural Biology 87, 102844, 2024
2024
Cryoradiolysis of oxygenated cytochrome P450 17A1 with lyase substrates generates expected products
R Usai, IG Denisov, SG Sligar, JR Kincaid
Journal of Inorganic Biochemistry 257, 112582, 2024
12024
Selective α-Hydroxyketone Formation and Subsequent C–C Bond Cleavage by Cytochrome P450 Monooxygenase Enzymes
JHZ Lee, T Coleman, MA Mclean, MN Podgorski, EF Hayball, ISJ Stone, ...
ACS Catalysis 14, 8958-8971, 2024
2024
Revealing KRas4b topology on the membrane surface
S Shree, MA McLean, AG Stephen, SG Sligar
Biochemical and Biophysical Research Communications 678, 122-127, 2023
22023
Tsuneo Omura-In memory of a Pioneer in cytochrome P450 research.
JH Dawson, SG Sligar
Journal of Inorganic Biochemistry, 112327-112327, 2023
2023
Solvent isotope effects in the catalytic cycle of P450 CYP17A1: Computational modeling of the hydroxylation and lyase reactions
IG Denisov, SG Sligar
Journal of inorganic biochemistry 243, 112202, 2023
32023
Engineering C–C bond cleavage activity into a P450 monooxygenase enzyme
JC Miller, JHZ Lee, MA Mclean, RR Chao, ISJ Stone, TL Pukala, ...
Journal of the American Chemical Society 145 (16), 9207-9222, 2023
112023
Midazolam as a probe for heterotropic drug-drug interactions mediated by CYP3A4
IG Denisov, YV Grinkova, MA McLean, T Camp, SG Sligar
Biomolecules 12 (6), 853, 2022
112022
Importance of asparagine 202 in manipulating active site structure and substrate preference for human CYP17A1
Y Liu, I Denisov, M Gregory, SG Sligar, JR Kincaid
Biochemistry 61 (7), 583-594, 2022
62022
Mechanism of the clinically relevant E305G mutation in human P450 CYP17A1
Y Liu, Y Grinkova, MC Gregory, IG Denisov, JR Kincaid, SG Sligar
Biochemistry 60 (43), 3262-3271, 2021
62021
Revealing the Structure and Function of Membrane Proteins
S Sligar
PROTEIN SCIENCE 30, 153-154, 2021
2021
A Pathfinder in High-Pressure Bioscience: In Memoriam of Gaston Hui Bon Hoa
DR Davydov, C Jung, GA Petsko, SG Sligar, JA Kornblatt
Biology 10 (8), 778, 2021
2021
Midazolam as a probe for drug–drug interactions mediated by cyp3a4: homotropic allosteric mechanism of site-specific hydroxylation
IG Denisov, YV Grinkova, T Camp, MA McLean, SG Sligar
Biochemistry 60 (21), 1670-1681, 2021
232021
Substrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome b5
Y Liu, IG Denisov, SG Sligar, JR Kincaid
Journal of the American Chemical Society 143 (10), 3729-3733, 2021
132021
Nanodiscs: A toolkit for membrane protein science
SG Sligar, IG Denisov
Protein Science 30 (2), 297-315, 2021
1112021
Biomimetic chemical sensors using nanoelectronic readout of olfactory receptors
AT Johnson Jr, BR Goldsmith, JJ Mitala, BM Discher, SG Sligar, ...
US Patent 10,900,971, 2021
2021
P450 CYP17A1 variant with a disordered proton shuttle assembly retains peroxo‐mediated lyase efficiency
Y Liu, IG Denisov, YV Grinkova, SG Sligar, JR Kincaid
Chemistry–A European Journal 26 (70), 16846-16852, 2020
92020
Dark, ultra-dark and ultra-bright nanodiscs for membrane protein investigations
MA McLean, IG Denisov, YV Grinkova, SG Sligar
Analytical biochemistry 607, 113860, 2020
62020
A modified vilsmeier–haack strategy to construct β-pyridine-fused 5, 10, 15, 20-tetraarylporphyrins
P Singh, M Nath
SynOpen 4 (02), 44-50, 2020
92020
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