Methods and applications of genome-wide profiling of DNA damage and rare mutations GP Pfeifer, SG Jin Nature Reviews Genetics, 1-18, 2024 | 1 | 2024 |
Homeobox and Polycomb target gene methylation in human solid tumors R Blanchett, KH Lau, GP Pfeifer Scientific Reports 14 (1), 13912, 2024 | | 2024 |
DNA Damage and Parkinson’s Disease GP Pfeifer International Journal of Molecular Sciences 25 (8), 4187, 2024 | 3 | 2024 |
SMCHD1 maintains heterochromatin and genome compartments in human myoblasts Z Huang, W Cui, I Ratnayake, R Tawil, GP Pfeifer bioRxiv, 2024.07. 07.602392, 2024 | | 2024 |
Deficiency of the Polycomb protein RYBP and TET methylcytosine oxidases promotes extensive CpG island hypermethylation and malignant transformation W Cui, Z Huang, SG Jin, J Johnson, KH Lau, G Hostetter, GP Pfeifer Cancer research 83 (15), 2480-2495, 2023 | 4 | 2023 |
Circle damage sequencing for whole-genome analysis of DNA damage SG Jin, J Johnson, GP Pfeifer Cancer Systems and Integrative Biology, 247-262, 2023 | 1 | 2023 |
Abstract A34: Mutant NPM1 hijacks active transcriptional machinery to maintain pathogenic gene programs in AML XQD Wang, D Fan, Y Liu, H Miao, D Chen, X Wang, H Gore, P Himadewi, ... Blood Cancer Discovery 4 (3_Supplement), A34-A34, 2023 | | 2023 |
The link between 5-hydroxymethylcytosine and DNA demethylation in early embryos GP Pfeifer, PE Szabó Epigenomics 15 (6), 335-339, 2023 | | 2023 |
Mutant NPM1 hijacks transcriptional hubs to maintain pathogenic gene programs in acute myeloid leukemia XQD Wang, D Fan, Q Han, Y Liu, H Miao, X Wang, Q Li, D Chen, H Gore, ... Cancer discovery 13 (3), 724-745, 2023 | 35 | 2023 |
TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis H Liu, Y Liu, SG Jin, J Johnson, H Xuan, D Lu, J Li, L Zhai, X Li, Y Zhao, ... Cell Reports 42 (1), 2023 | 5 | 2023 |
5-hydroxymethylcytosine stabilizes transcription by preventing aberrant initiation in gene bodies GP Pfeifer Nature Genetics 55 (1), 2-3, 2023 | 2 | 2023 |
Methods for Analyzing DNA Cytosine Modifications Genome-wide TA Rauch, GP Pfeifer Handbook of Epigenetics, 123-135, 2023 | 1 | 2023 |
UVA Radiation, DNA damage, and melanoma SG Jin, F Padron, GP Pfeifer ACS omega 7 (37), 32936-32948, 2022 | 30 | 2022 |
Arthur D. Riggs 1939–2022 GP Pfeifer, J Singer-Sam, K Itakura Nature Biotechnology 40 (9), 1317-1318, 2022 | | 2022 |
Dysfunction of the Polycomb protein RYBP and of 5-methylcytosine oxidases leads to widespread CpG island hypermethylation and cell transformation W Cui, Z Huang, SG Jin, J Johnson, G Hostetter, GP Pfeifer bioRxiv, 2022.07. 26.501603, 2022 | | 2022 |
Z-DNA is remodelled by ZBTB43 in prospermatogonia to safeguard the germline genome and epigenome Y Meng, G Wang, H He, KH Lau, A Hurt, BJ Bixler, A Parham, SG Jin, ... Nature Cell Biology 24 (7), 1141-1153, 2022 | 14 | 2022 |
Concordance of hydrogen peroxide–induced 8-oxo-guanine patterns with two cancer mutation signatures of upper GI tract tumors SG Jin, Y Meng, J Johnson, PE Szabó, GP Pfeifer Science Advances 8 (22), eabn3815, 2022 | 20 | 2022 |
Lack of major genome-wide DNA methylation changes in succinate-treated human epithelial cells W Cui, Z Huang, GP Pfeifer International Journal of Molecular Sciences 23 (10), 5663, 2022 | 2 | 2022 |
The ups and downs of DNA methylation: an interview with Gerd Pfeifer GP Pfeifer Epigenomics 14 (6), 339-343, 2022 | 1 | 2022 |
3′ HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression P Himadewi, XQD Wang, F Feng, H Gore, Y Liu, L Yu, R Kurita, ... Elife 10, e70557, 2021 | 12 | 2021 |