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Laura M. Bohn, PhD
Laura M. Bohn, PhD
The Herbert Wertheim UF Scripps Biomedical Institute for Technology & Innovation
在 ufl.edu 的电子邮件经过验证
标题
引用次数
年份
Structural and functional insights into the G protein-coupled receptors: CB1 and CB2
CA Brust, MA Swanson, LM Bohn
Biochemical Society Transactions 51 (4), 1533-1543, 2023
22023
A Route to Potent, Selective, and Biased Salvinorin Chemical Space
SJ Hill, N Dao, VQ Dang, EL Stahl, LM Bohn, RA Shenvi
ACS Central Science 9 (8), 1567-1574, 2023
62023
Hyperactivity in mice induced by opioid agonists with partial intrinsic efficacy and biased agonism administered alone and in combination with morphine
A Acevedo-Canabal, TW Grim, CL Schmid, N McFague, EL Stahl, ...
Biomolecules 13 (6), 935, 2023
12023
Hyperactivity in mice induced by opioid agonists with partial intrinsic efficacy and biased agonism; alone and in combination with morphine
A Acevedo-Canabal, TW Grim, CL Schmid, N McFague, EL Stahl, ...
bioRxiv, 2023.05. 11.540403, 2023
2023
Synthesis of 20-nor-salvinorin A
R Shenvi, J Roach, Y Sasano, L Bohn, C Schmid
US Patent 11,512,075, 2022
2022
Asymmetric Syntheses of (+)- and (−)-Collybolide Enable Reevaluation of kappa-Opioid Receptor Agonism
SL Shevick, SM Freeman, G Tong, RJ Russo, LM Bohn, RA Shenvi
ACS Central Science 8 (7), 948-954, 2022
42022
Community guidelines for GPCR ligand bias: IUPHAR review 32
P Kolb, T Kenakin, SPH Alexander, M Bermudez, LM Bohn, CS Breinholt, ...
British journal of pharmacology 179 (14), 3651-3674, 2022
1202022
Functional analysis of key residues involved in CB1 and CB2 activation
CA Brust, JH Ho, E Stahl, C Iliopoulos‐Tsoutsouvas, S Nikas, ...
The FASEB Journal 36, 2022
2022
Irreversible and noncompetitive mu opioid receptor agonists
E Stahl, CL Schmid, A Acevedo‐Canabal, C Read, T Grim, NM Kennedy, ...
The FASEB Journal 36, 2022
2022
Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance
H Ma, T Brust, KJ Frankowski, KM Lovell, MD Cameron, LM Bohn, J Aube
ACS Chemical Neuroscience 13 (8), 1315-1332, 2022
12022
Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists
IP Papanastasiou, MO Georgiadis, C Iliopoulos-Tsoutsouvas, CA Paronis, ...
European Journal of Medicinal Chemistry 230, 114027, 2022
32022
Pharmacological Diversity in Opioid Analgesics: Lessons From Clinically Useful Drugs
A Acevedo-Canabal, F Pantouli, A Ravichandran, L Rullo, LM Bohn
Elsevier, 2022
22022
G protein signaling–biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists
EL Stahl, CL Schmid, A Acevedo-Canabal, C Read, TW Grim, ...
Proceedings of the National Academy of Sciences 118 (48), e2102178118, 2021
212021
A genetically encoded F-19 NMR probe reveals the allosteric modulation mechanism of cannabinoid receptor 1
X Wang, D Liu, L Shen, F Li, Y Li, L Yang, T Xu, H Tao, D Yao, L Wu, ...
Journal of the American Chemical Society 143 (40), 16320-16325, 2021
592021
Low intrinsic efficacy alone cannot explain the improved side effect profiles of new opioid agonists
EL Stahl, LM Bohn
Biochemistry 61 (18), 1923-1935, 2021
402021
Some effects of putative G-protein biased mu-opioid receptor agonists in male rhesus monkeys
JC Cornelissen, BE Blough, LM Bohn, SS Negus, ML Banks
Behavioural pharmacology 32 (5), 453-458, 2021
62021
Structure–activity relationship investigation of triazole-based kappa opioid receptor agonists
KJ Frankowski, T Brust, KM Lovell, E Yoo, LM Bohn, J Aubé
Medicinal Chemistry Research 30 (7), 1386-1396, 2021
22021
Decaf or regular? Energizing the caffeine receptor
EL Stahl, LM Bohn
Cell 184 (7), 1659-1660, 2021
2021
Novel functionalized cannabinoid receptor probes: Development of exceptionally potent agonists
S Jiang, C Iliopoulos-Tsoutsouvas, F Tong, CA Brust, CM Keenan, ...
Journal of Medicinal Chemistry 64 (7), 3870-3884, 2021
102021
Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain
F Pantouli, TW Grim, CL Schmid, A Acevedo-Canabal, NM Kennedy, ...
Neuropharmacology 185, 108439, 2021
192021
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