Structural and functional insights into the G protein-coupled receptors: CB1 and CB2 CA Brust, MA Swanson, LM Bohn Biochemical Society Transactions 51 (4), 1533-1543, 2023 | 2 | 2023 |
A Route to Potent, Selective, and Biased Salvinorin Chemical Space SJ Hill, N Dao, VQ Dang, EL Stahl, LM Bohn, RA Shenvi ACS Central Science 9 (8), 1567-1574, 2023 | 6 | 2023 |
Hyperactivity in mice induced by opioid agonists with partial intrinsic efficacy and biased agonism administered alone and in combination with morphine A Acevedo-Canabal, TW Grim, CL Schmid, N McFague, EL Stahl, ... Biomolecules 13 (6), 935, 2023 | 1 | 2023 |
Hyperactivity in mice induced by opioid agonists with partial intrinsic efficacy and biased agonism; alone and in combination with morphine A Acevedo-Canabal, TW Grim, CL Schmid, N McFague, EL Stahl, ... bioRxiv, 2023.05. 11.540403, 2023 | | 2023 |
Synthesis of 20-nor-salvinorin A R Shenvi, J Roach, Y Sasano, L Bohn, C Schmid US Patent 11,512,075, 2022 | | 2022 |
Asymmetric Syntheses of (+)- and (−)-Collybolide Enable Reevaluation of kappa-Opioid Receptor Agonism SL Shevick, SM Freeman, G Tong, RJ Russo, LM Bohn, RA Shenvi ACS Central Science 8 (7), 948-954, 2022 | 4 | 2022 |
Community guidelines for GPCR ligand bias: IUPHAR review 32 P Kolb, T Kenakin, SPH Alexander, M Bermudez, LM Bohn, CS Breinholt, ... British journal of pharmacology 179 (14), 3651-3674, 2022 | 120 | 2022 |
Functional analysis of key residues involved in CB1 and CB2 activation CA Brust, JH Ho, E Stahl, C Iliopoulos‐Tsoutsouvas, S Nikas, ... The FASEB Journal 36, 2022 | | 2022 |
Irreversible and noncompetitive mu opioid receptor agonists E Stahl, CL Schmid, A Acevedo‐Canabal, C Read, T Grim, NM Kennedy, ... The FASEB Journal 36, 2022 | | 2022 |
Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance H Ma, T Brust, KJ Frankowski, KM Lovell, MD Cameron, LM Bohn, J Aube ACS Chemical Neuroscience 13 (8), 1315-1332, 2022 | 1 | 2022 |
Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists IP Papanastasiou, MO Georgiadis, C Iliopoulos-Tsoutsouvas, CA Paronis, ... European Journal of Medicinal Chemistry 230, 114027, 2022 | 3 | 2022 |
Pharmacological Diversity in Opioid Analgesics: Lessons From Clinically Useful Drugs A Acevedo-Canabal, F Pantouli, A Ravichandran, L Rullo, LM Bohn Elsevier, 2022 | 2 | 2022 |
G protein signaling–biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists EL Stahl, CL Schmid, A Acevedo-Canabal, C Read, TW Grim, ... Proceedings of the National Academy of Sciences 118 (48), e2102178118, 2021 | 21 | 2021 |
A genetically encoded F-19 NMR probe reveals the allosteric modulation mechanism of cannabinoid receptor 1 X Wang, D Liu, L Shen, F Li, Y Li, L Yang, T Xu, H Tao, D Yao, L Wu, ... Journal of the American Chemical Society 143 (40), 16320-16325, 2021 | 59 | 2021 |
Low intrinsic efficacy alone cannot explain the improved side effect profiles of new opioid agonists EL Stahl, LM Bohn Biochemistry 61 (18), 1923-1935, 2021 | 40 | 2021 |
Some effects of putative G-protein biased mu-opioid receptor agonists in male rhesus monkeys JC Cornelissen, BE Blough, LM Bohn, SS Negus, ML Banks Behavioural pharmacology 32 (5), 453-458, 2021 | 6 | 2021 |
Structure–activity relationship investigation of triazole-based kappa opioid receptor agonists KJ Frankowski, T Brust, KM Lovell, E Yoo, LM Bohn, J Aubé Medicinal Chemistry Research 30 (7), 1386-1396, 2021 | 2 | 2021 |
Decaf or regular? Energizing the caffeine receptor EL Stahl, LM Bohn Cell 184 (7), 1659-1660, 2021 | | 2021 |
Novel functionalized cannabinoid receptor probes: Development of exceptionally potent agonists S Jiang, C Iliopoulos-Tsoutsouvas, F Tong, CA Brust, CM Keenan, ... Journal of Medicinal Chemistry 64 (7), 3870-3884, 2021 | 10 | 2021 |
Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain F Pantouli, TW Grim, CL Schmid, A Acevedo-Canabal, NM Kennedy, ... Neuropharmacology 185, 108439, 2021 | 19 | 2021 |