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Collin Tokheim
Collin Tokheim
在 astrazeneca.com 的电子邮件经过验证
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Critical assessment of genome interpretation consortium. CAGI, the critical assessment of genome interpretation, establishes progress and pprospects for computational genetic …
S Jain, C Bakolitsa, EB Steven, P Radivojac, J Moult, S Repo, AH Roger, ...
Genome Biology 22 (22; 25 (1): 53.), 1-46, 2024
2024
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
N Null, S Jain, C Bakolitsa, SE Brenner, P Radivojac, J Moult, S Repo, ...
Genome Biology 25 (1), 1-46, 2024
32024
Pan-cancer proteogenomics connects oncogenic drivers to functional states
Y Li, E Porta-Pardo, C Tokheim, MH Bailey, TM Yaron, V Stathias, ...
Cell 186 (18), 3921-3944. e25, 2023
252023
Tutorial: integrative computational analysis of bulk RNA-sequencing data to characterize tumor immunity using RIMA
L Yang, J Wang, J Altreuter, A Jhaveri, CJ Wong, L Song, J Fu, L Taing, ...
Nature Protocols 18 (8), 2404-2414, 2023
62023
Discovery of targets for immune–metabolic antitumor drugs identifies estrogen-related receptor alpha
A Sahu, X Wang, P Munson, JPG Klomp, X Wang, SS Gu, Y Han, G Qian, ...
Cancer discovery 13 (3), 672-701, 2023
122023
Machine learning modeling of protein-intrinsic features predicts tractability of targeted protein degradation
W Zhang, SS Roy Burman, J Chen, KA Donovan, Y Cao, C Shu, B Zhang, ...
Genomics, Proteomics and Bioinformatics 20 (5), 882-898, 2022
172022
Charting the spatial landscape of cancer hallmarks
M Sibai, S Cervilla, D Grases, E Musulen, A Fortian, M Romeo, A Bernat, ...
bioRxiv, 2022
12022
Genetic fusions favor tumorigenesis through degron loss in oncogenes
J Liu, C Tokheim, JD Lee, W Gan, BJ North, XS Liu, PP Pandolfi, W Wei
Nature Communications 12 (1), 6704, 2021
182021
In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
X Wang, C Tokheim, SS Gu, B Wang, Q Tang, Y Li, N Traugh, Z Zeng, ...
Cell 184 (21), 5357-5374. e22, 2021
962021
Cross-site concordance evaluation of tumor DNA and RNA sequencing platforms for the CIMAC-CIDC Network
Z Zeng, J Fu, C Cibulskis, A Jhaveri, C Gumbs, B Das, ...
Clinical Cancer Research 27 (18), 5049-5061, 2021
62021
Therapeutically increasing MHC-I expression potentiates immune checkpoint blockade
SS Gu, W Zhang, X Wang, P Jiang, N Traugh, Z Li, C Meyer, B Stewig, ...
Cancer discovery 11 (6), 1524-1541, 2021
1162021
Systematic characterization of mutations altering protein degradation in human cancers
C Tokheim, X Wang, RT Timms, B Zhang, EL Mena, B Wang, C Chen, ...
Molecular cell 81 (6), 1292-1308. e11, 2021
442021
The genetic evolution of treatment-resistant cutaneous, acral, and uveal melanomas
AP Makohon-Moore, EJ Lipson, JE Hooper, A Zucker, J Hong, CM Bielski, ...
Clinical Cancer Research 27 (5), 1516-1525, 2021
82021
Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
SS Gu, X Wang, X Hu, P Jiang, Z Li, N Traugh, X Bu, Q Tang, C Wang, ...
Genome biology 21, 1-28, 2020
172020
Determinants of transcription factor regulatory range
CH Chen, R Zheng, C Tokheim, X Dong, J Fan, C Wan, Q Tang, M Brown, ...
Nature communications 11 (1), 2472, 2020
472020
Integrated informatics analysis of cancer-related variants
KA Pagel, R Kim, K Moad, B Busby, L Zheng, C Tokheim, M Ryan, ...
JCO clinical cancer informatics 4, 310-317, 2020
772020
High-throughput prediction of MHC class I and II neoantigens with MHCnuggets
XM Shao, R Bhattacharya, J Huang, IKA Sivakumar, C Tokheim, L Zheng, ...
Cancer immunology research 8 (3), 396-408, 2020
1242020
CHASMplus reveals the scope of somatic missense mutations driving human cancers
C Tokheim, R Karchin
Cell systems 9 (1), 9-23. e8, 2019
982019
A pan-cancer analysis reveals high-frequency genetic alterations in mediators of signaling by the TGF-β superfamily
A Korkut, S Zaidi, RS Kanchi, S Rao, NR Gough, A Schultz, X Li, ...
Cell systems 7 (4), 422-437. e7, 2018
1452018
Minimal functional driver gene heterogeneity among untreated metastases
JG Reiter, AP Makohon-Moore, JM Gerold, A Heyde, MA Attiyeh, ...
Science 361 (6406), 1033-1037, 2018
2792018
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