Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations PP Lowe, C Morel, A Ambade, A Iracheta-Vellve, E Kwiatkowski, ... Journal of neuroinflammation 17, 1-18, 2020 | 57 | 2020 |
DEFINING THE ONSET OF FIBROSIS IN A CDAA DIET INDUCED MOUSE MODEL OF NON-ALCOHOLIC STEATOHEPATITIS USING RNA-SEQ/PATHWAY PROFILING. A Ambade, F Lewis, G Kolumam, JP Morrison, J Cornicelli HEPATOLOGY 72, 908A-908A, 2020 | | 2020 |
VALIDATION OF THE OB/OB MOUSE MODEL FOR NASH PROGRESSION BY TRANSCRIPTIONAL PROFILING OF MOUSE LIVER USING RNA-SEQ V Goelela, M Fokkelman, A Ambade, ME Kirkland, NT Jones, C Zhang, ... HEPATOLOGY 70, 1068A-1069A, 2019 | | 2019 |
CHANGE IN DIET REVERSES NASH IN CDAA DIET INDUCED MOUSE MODEL ALONG WITH IMPROVEMENT OF OVERALL LIVER FUNCTION. S Perrotta, A Ambade, J Al-Beik, K Bayer, ME Kirkland, NT Jones, ... HEPATOLOGY 70, 1317A-1317A, 2019 | | 2019 |
Alcohol-induced IL-17A production in Paneth cells amplifies endoplasmic reticulum stress, apoptosis, and inflammasome-IL-18 activation in the proximal small intestine in mice B Gyongyosi, Y Cho, P Lowe, CD Calenda, A Iracheta-Vellve, ... Mucosal immunology 12 (4), 930-944, 2019 | 41 | 2019 |
Sa1500–Alcohol Induced Il-17A Production in Paneth Cells Amplifies Endoplasmic Reticulum Stress and Inflammasome-Il-18 Activation in the Proximal Small Intestine in Mice Y Cho, P Lowe, B Gyöngyösi, CD Calenda, A Iracheta-Vellve, ... Gastroenterology 156 (6), S-1225, 2019 | | 2019 |
Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol‐Induced Liver Damage, Steatosis, and Inflammation in Mice A Ambade, P Lowe, K Kodys, D Catalano, B Gyongyosi, Y Cho, ... Hepatology 69 (3), 1105-1121, 2019 | 177 | 2019 |
Macrophage‐Specific Hypoxia‐Inducible Factor‐1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis X Wang, M de Carvalho Ribeiro, A Iracheta‐Vellve, P Lowe, A Ambade, ... Hepatology 69 (2), 545-563, 2019 | 104 | 2019 |
Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, Y Cho, ... Journal of neuroinflammation 15, 1-12, 2018 | 113 | 2018 |
FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice A Iracheta‐Vellve, CD Calenda, J Petrasek, A Ambade, K Kodys, ... Hepatology communications 2 (11), 1379-1391, 2018 | 92 | 2018 |
Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use TN Bukong, Y Cho, A Iracheta-Vellve, B Saha, P Lowe, A Adejumo, I Furi, ... Journal of hepatology 69 (5), 1145-1154, 2018 | 125 | 2018 |
Harmful Neutrophils in Alcoholic Hepatitis: Increased Extracellular Traps (NETs) in Patients and Attenuated Liver Injury after Neutrophil Depletion in Mice Y Cho, T Bukong, A Ambade, P Lowe, D Catalano, K Kodys, G Szabo HEPATOLOGY 68, 942A-942A, 2018 | | 2018 |
LIVER-BRAIN-AXIS IN ALD: CHRONIC ALCOHOL INDUCES RECRUITMENT OF PERIPHERAL MACROPHAGES WITH DIFFERENT INFLAMMATORY EXPRESSION PROFILES INTO THE LIVER AND BRAIN P Lowe, A Ambade, A Iracheta-Vellve, I Furi, B Gyongyosi, D Catalano, ... ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 42, 104A-104A, 2018 | | 2018 |
MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients From Ethanol-Induced Liver Disease A Satishchandran, A Ambade, S Rao, YC Hsueh, A Iracheta-Vellve, ... Gastroenterology 154 (1), 238-252. e7, 2018 | 141 | 2018 |
Manuscript Review and Publication DYR Stainier, E Raz, ND Lawson, SC Ekker, RD Burdine, JS Eisen, ... Viewpoints, 2017 | | 2017 |
Liver-brain axis in alcoholic liver disease: Chronic alcohol induces recruitment of peripheral macrophages with different inflammatory gene expression profile into the liver … PP Lowe, A Ambade, A Iracheta-Vellve, I Furi, B Gyongyosi, D Catalano, ... HEPATOLOGY 66, 690A-690A, 2017 | | 2017 |
Alcohol‐induced miR‐155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease S Bala, T Csak, K Kodys, D Catalano, A Ambade, I Furi, P Lowe, Y Cho, ... Journal of leukocyte biology 102 (2), 487-498, 2017 | 86 | 2017 |
Correction: Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice. PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, A Ambade, ... PloS one 12 (5), e0179070, 2017 | 8 | 2017 |
Reduced Neutrophil Extracellular Trap Formation and their Impaired Clearance by Macrophages Exacerbates Liver Injury in Alcoholic Liver Disease TN Bukong, B Saha, A Iracheta-Vellve, AC Adejumo, I Furi, A Ambade, ... Gastroenterology 152 (5), S1111, 2017 | | 2017 |
miR-155 Dependent Dysregulation of Autophagy in Hepatocytes and Macrophages Drives the Development of Ald By Exploiting the Exosomal Pathway I Furi, TN Bukong, S Bala, P Lowe, A Iracheta-Vellve, K Kodys, A Ambade, ... Gastroenterology 152 (5), S1046, 2017 | | 2017 |