Vocal learning–associated convergent evolution in mammalian proteins and regulatory elements ME Wirthlin, TA Schmid, JE Elie, X Zhang, A Kowalczyk, R Redlich, ... Science 383 (6690), eabn3263, 2024 | 5 | 2024 |
Single nuclei transcriptomics in human and non-human primate striatum in opioid use disorder BDN Phan, MH Ray, X Xue, C Fu, RJ Fenster, SJ Kohut, J Bergman, ... Nature Communications 15 (1), 878, 2024 | 4* | 2024 |
Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes HY Chen, BDN Phan, G Shim, GR Hamersky, N Sadowski, TS O’Donnell, ... Molecular psychiatry 28 (11), 4679-4692, 2023 | 1 | 2023 |
Integrative multi-dimensional characterization of striatal projection neuron heterogeneity in adult brain J Gayden, S Puig, C Srinivasan, BDN Phan, G Abdelhady, SA Buck, ... bioRxiv, 2023 | 3* | 2023 |
Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs KL Moon, HJ Huson, K Morrill, MS Wang, X Li, K Srikanth, Z Consortium, ... Science 380 (6643), eabn5887, 2023 | 7 | 2023 |
The contribution of historical processes to contemporary extinction risk in placental mammals AP Wilder, MA Supple, A Subramanian, A Mudide, R Swofford, ... Science 380 (6643), eabn5856, 2023 | 28 | 2023 |
The functional and evolutionary impacts of human-specific deletions in conserved elements JR Xue, A Mackay-Smith, K Mouri, MF Garcia, MX Dong, JF Akers, ... Science 380 (6643), eabn2253, 2023 | 17 | 2023 |
Insights into mammalian TE diversity through the curation of 248 genome assemblies AB Osmanski, NS Paulat, J Korstian, JR Grimshaw, M Halsey, ... Science 380 (6643), eabn1430, 2023 | 31 | 2023 |
A genomic timescale for placental mammal evolution NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ... Science 380 (6643), eabl8189, 2023 | 52 | 2023 |
Integrating gene annotation with orthology inference at scale BM Kirilenko, C Munegowda, E Osipova, D Jebb, V Sharma, M Blumer, ... Science 380 (6643), eabn3107, 2023 | 49 | 2023 |
Three-dimensional genome rewiring in loci with human accelerated regions KC Keough, S Whalen, F Inoue, PF Przytycki, T Fair, C Deng, M Steyert, ... Science 380 (6643), eabm1696, 2023 | 33 | 2023 |
Mammalian evolution of human cis-regulatory elements and transcription factor binding sites G Andrews, K Fan, HE Pratt, N Phalke, Zoonomia Consortium §, ... Science 380 (6643), eabn7930, 2023 | 30 | 2023 |
Leveraging base-pair mammalian constraint to understand genetic variation and human disease PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li, DP Genereux, ... Science 380 (6643), eabn2937, 2023 | 42 | 2023 |
Evolutionary constraint and innovation across hundreds of placental mammals MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ... Science 380 (6643), eabn3943, 2023 | 93 | 2023 |
Relating enhancer genetic variation across mammals to complex phenotypes using machine learning IM Kaplow, AJ Lawler, DE Schäffer, C Srinivasan, HH Sestili, ME Wirthlin, ... Science 380 (6643), eabm7993, 2023 | 25 | 2023 |
Regression convolutional neural network models implicate peripheral immune regulatory variants in the predisposition to Alzheimer’s disease E Ramamurthy, S Agarwal, N Toong, IM Kaplow, BD Phan, AR Pfenning bioRxiv, 2022.12. 02.518903, 2022 | | 2022 |
An in vivo massively parallel platform for deciphering tissue-specific regulatory function AR Brown, GA Fox, IM Kaplow, AJ Lawler, BDN Phan, ME Wirthlin, ... bioRxiv, 2022.11. 23.517755, 2022 | 3 | 2022 |
Olfactory and neurological outcomes of SARS-CoV-2 from acute infection to recovery DD Desai, SE Yu, B Salvatore, Z Goldberg, EMR Bowers, JA Moore, ... Frontiers in Allergy 3, 1019274, 2022 | 3 | 2022 |
Inhibiting the type 2 inflammatory pathway with dupilumab is associated with an increase in interleukin‐4 and interleukin‐18 production. J Morris, TF Olonisakin, JA Moore, BD Phan, DM Parker, BA Uribe, ... International Forum of Allergy & Rhinology 12 (10), 2022 | | 2022 |
Machine learning sequence prioritization for cell type-specific enhancer design AJ Lawler, E Ramamurthy, AR Brown, N Shin, Y Kim, N Toong, IM Kaplow, ... Elife 11, e69571, 2022 | 14 | 2022 |