Let it be: Preserving tumor-draining lymph nodes in the era of immuno-oncology R Saddawi-Konefka, S Schokrpur, JS Gutkind Cancer Cell 42 (6), 930-933, 2024 | | 2024 |
A phase 2 study of ipatasertib in combination with pembrolizumab for first-line treatment of recurrent or metastatic squamous cell cancer of the head and neck. JS Thomas, J Yang Bruce, Z Li, JH Lorch, T Phillips, V Villaflor, C Ruel, ... Journal of Clinical Oncology 42 (16_suppl), TPS6117-TPS6117, 2024 | | 2024 |
CTEP 10492, a phase 1/1b study of the AKT inhibitor ipatasertib with chemoradiation for locally advanced head and neck squamous cell carcinoma. MD Mattes, H Willers, Y Lin, LA Gharzai, ER Alesi, CE Lominska, S Kim, ... Journal of Clinical Oncology 42 (16_suppl), TPS6127-TPS6127, 2024 | | 2024 |
Structural Dynamics in RhoGEF Signaling Investigated Using Model Cell Membranes J Cash, S Ravala, SR Adame-Garcia, S Li, CL Chen, M Cianfrocco, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
Mouse Models for Head and Neck Squamous Cell Carcinoma J Zhou, C Liu, P Amornphimoltham, SC Cheong, JS Gutkind, Q Chen, ... Journal of Dental Research, 00220345241240997, 2024 | | 2024 |
The landscape of cancer-rewired GPCR signaling axes C Arora, M Matic, L Bisceglia, P Di Chiaro, NDO Rosa, F Carli, L Clubb, ... Cell Genomics 4 (5), 2024 | 2 | 2024 |
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer F Haderk, YT Chou, L Cech, C Fernández-Méndez, J Yu, V Olivas, ... Nature Communications 15 (1), 3741, 2024 | 10 | 2024 |
Dysregulation of the Hippo pathway enhances PD-L2 transcription to promote cancer immune evasion T Ando, K Okamoto, K Sato, Y Goto, H Izumi, N Kataoka, Y Ueda, ... | | 2024 |
Many paths lead to immunology AJ García-Sáez, AI Domingos, JS Gutkind, S Mattoo, P Du Cell 187 (9), 2117-2119, 2024 | | 2024 |
Abstract CT260: A phase II trial of defactinib combined with avutometinib in patients with metastatic uveal melanoma RS Seedor, M Terai, A Majeed, R Tanaka, AE Aplin, M Orloff, AA Molinolo, ... Cancer Research 84 (7_Supplement), CT260-CT260, 2024 | | 2024 |
Abstract SY39-03: Illuminating the tumor immune GPCRome: Novel immunotherapy targets JS Gutkind Cancer Research 84 (7_Supplement), SY39-03-SY39-03, 2024 | | 2024 |
A novel combination therapy targeting RAF, MEK and FAK to overcome skin cutaneous melanoma treatment resistance S Lubrano, F Faraji, RD Cervantes-Villagrana, S Ramirez, N Arang, ... Cancer Research 84 (6_Supplement), 4745-4745, 2024 | | 2024 |
YAP-driven epigenetic reprogramming in head and neck cancer A Officer, F Faraji, S Ramirez, A Goren, P Tamayo, JS Gutkind Cancer Research 84 (6_Supplement), 1707-1707, 2024 | | 2024 |
Genome-wide CRISPR screening reveals a central role for ferroptotic cell death in the anti-tumor response to mTOR inhibitors in HNSCC K Koshizuka, X Wu, K Sato, PT Vo, GM Murawska, T Ishikawa, Z Wang, ... Cancer Research 84 (6_Supplement), 5996-5996, 2024 | | 2024 |
An ex-vivo organotypic culture platform of mucinous carcinomatosis peritonei identifies CDK4-6 inhibition as a novel treatment J Weitz, D Nishizaki, J Patel, I Ng, S Sun, D Ramms, J Zou, J Baumgartner, ... Cancer Research 84 (6_Supplement), 6777-6777, 2024 | | 2024 |
Structural dynamics in RhoGEF signaling investigated using model cell membranes S Ravala, S Adame-Garcia, S Li, CL Chen, MA Cianfrocco, JS Gutkind, ... Biophysical Journal 123 (3), 152a, 2024 | | 2024 |
CHMP2A regulates broad immune cell-mediated antitumor activity in an immunocompetent in vivo head and neck squamous cell carcinoma model J Yun, R Saddawi-Konefka, B Goldenson, R Al-Msari, D Bernareggi, ... Journal for Immunotherapy of Cancer 12 (5), 2024 | | 2024 |
Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion OM Chaim, S Miki, BC Prager, J Ma, AY Jeong, J Lara, NK Tran, JM Smith, ... Scientific Reports 13 (1), 22412, 2023 | | 2023 |
Akt Is Controlled by Bag5 through a Monoubiquitination to Polyubiquitination Switch I Bracho-Valdés, RD Cervantes-Villagrana, YM Beltrán-Navarro, ... International Journal of Molecular Sciences 24 (24), 17531, 2023 | | 2023 |
Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma U Baqai, AM Kurimchak, IV Trachtenberg, TJ Purwin, JI Haj, A Han, K Luo, ... Journal of Biological Chemistry 299 (12), 2023 | 2 | 2023 |