Effects of Salvia officinalis L. and Chamaemelum nobile (L.) extracts on inflammatory responses in two models of human cells: Primary subcutaneous adipocytes and neuroblastoma … C Russo, KD Edwards, G Margetts, S Kleidonas, NS Zaibi, JC Clapham, ... Journal of Ethnopharmacology 268, 113614, 2021 | 14 | 2021 |
Sixty years of drug discovery for type 2 diabetes: where are we now? JC Clapham Type 2 Diabetes: Methods and Protocols, 1-30, 2020 | 15 | 2020 |
Effects of a specific MCHR1 antagonist (GW803430) on energy budget and glucose metabolism in diet-induced obese mice. ZLN Zhang LiNa, R Sinclair, C Selman, S Mitchell, D Morgan, ... | | 2014 |
Effects of a specific MCHR1 antagonist (GW803430) on energy budget and glucose metabolism in diet‐induced obese mice LN Zhang, R Sinclair, C Selman, S Mitchell, D Morgan, JC Clapham, ... Obesity 22 (3), 681-690, 2014 | 10 | 2014 |
NFκB as a potent regulator of inflammation in human adipose tissue, influenced by depot, adiposity, T2DM status, and TNFα AL Harte, G Tripathi, MK Piya, TM Barber, JC Clapham, N Al‐Daghri, ... Obesity 21 (11), 2322-2330, 2013 | 24 | 2013 |
Nicholas C. Turner Nicholas C. Turner received his PhD from the Uni-versity of London in 1982. He joined SmithKline Beecham in 1991 as Senior Pharmacologist. His research … JC Clapham Progress in Drug Research 51, 34, 2013 | | 2013 |
Central control of thermogenesis JC Clapham Neuropharmacology 63 (1), 111-123, 2012 | 127 | 2012 |
Factors predicting nongenetic variability in body weight gain induced by a high-fat diet in inbred C57BL/6J mice. ZLN Zhang LiNa, DG Morgan, JC Clapham, JR Speakman | | 2012 |
Factors predicting nongenetic variability in body weight gain induced by a high‐fat diet in inbred C57BL/6J mice LN Zhang, DG Morgan, JC Clapham, JR Speakman Obesity 20 (6), 1179-1188, 2012 | 39 | 2012 |
Effects of chronic oral rimonabant administration on energy budgets of diet-induced obese C57BL/6 mice. ZLN Zhang LiNa, Y Gamo, R Sinclair, SE Mitchell, DG Morgan, ... | | 2012 |
Effects of chronic oral rimonabant administration on energy budgets of diet‐induced obese C57BL/6 mice LN Zhang, Y Gamo, R Sinclair, SE Mitchell, DG Morgan, JC Clapham, ... Obesity 20 (5), 954-962, 2012 | 17 | 2012 |
Physiological and behavioral responses to intermittent starvation in C57BL/6J mice LN Zhang, SE Mitchell, C Hambly, DG Morgan, JC Clapham, ... Physiology & behavior 105 (2), 376-387, 2012 | 56 | 2012 |
Physiological and behavioral responses to intermittent starvation in C57BL/6J mice. ZLN Zhang LiNa, SE Mitchell, C Hambly, DG Morgan, JC Clapham, ... | | 2011 |
Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity JR Speakman, DA Levitsky, DB Allison, MS Bray, JM De Castro, DJ Clegg, ... Disease models & mechanisms 4 (6), 733-745, 2011 | 372 | 2011 |
Targeting thermogenesis and related pathways in anti-obesity drug discovery JC Clapham, JRS Arch Pharmacology & therapeutics 131 (3), 295-308, 2011 | 34 | 2011 |
Binding properties of antagonists to cannabinoid receptors in intact cells M Wennerberg, L Cheng, S Hjorth, JC Clapham, A Balendran, ... Fundamental & clinical pharmacology 25 (2), 200-210, 2011 | 17 | 2011 |
Mitochondrial bioenergetics changes are induced by metabolic endotoxinaemia contributing to mitochondrial stress and dysfunction in human adipocytes KC McGee, AL Harte, J Oscarsson, A Brown, N Fernandes Da Silva, ... Diabetologia 54, S16-S16, 2011 | | 2011 |
Unravelling the complex dissociation of [3H]‐rimonabant from plated CB1 cannabinoid receptor‐expressing cells M Wennerberg, A Balendran, JC Clapham, G Vauquelin Fundamental & clinical pharmacology 24 (2), 181-187, 2010 | 10 | 2010 |
Metabolic endotoxaemia as a mediator of mitochondrial dysfunction in human adipose tissue, alleviated by salicylate KC McGee, G Tripathi, SJ Creely, AL Harte, M Langowska, NF Da Silva, ... Diabetologia 53 (Suppl. 1), S285, 2010 | | 2010 |
Effect of Lipopolysaccharide and Salicylate on Mitochondrial Gene Expression in Primary Human Adipocytes KC McGee, G Tripathi, AL Harte, M Langowska, NF Da Silva, J Oscarsson, ... Diabetes 59, A390-A390, 2010 | | 2010 |