Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma B Meyer, C Stirzaker, S Ramkomuth, K Harvey, B Chan, CS Lee, R Karim, ... The Journal of pathology 262 (4), 480-494, 2024 | 1 | 2024 |
Characterisation and reproducibility of the HumanMethylationEPIC v2. 0 BeadChip for DNA methylation profiling TJ Peters, B Meyer, L Ryan, J Achinger-Kawecka, J Song, EM Campbell, ... BMC genomics 25 (1), 251, 2024 | 3 | 2024 |
The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer J Achinger-Kawecka, C Stirzaker, N Portman, E Campbell, KM Chia, Q Du, ... Nature Structural & Molecular Biology 31 (3), 498-512, 2024 | 3 | 2024 |
18P A translational project of the WSG-ADAPT-TN trial demonstrates immunomodulatory and anti-viral defense gene networks predicting pathological complete response (pCR) and … M Graeser, N Harbeck, O Gluz, UA Nitz, M Christgen, S Kuemmel, ... ESMO Open 8 (1), 2023 | | 2023 |
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma JF Hastings, SL Latham, A Kamili, MS Wheatley, JZR Han, ... Science Advances 9 (9), eabp8314, 2023 | 7 | 2023 |
Comprehensive methylome sequencing reveals prognostic epigenetic biomarkers for prostate cancer mortality R Pidsley, D Lam, W Qu, TJ Peters, PL Luu, D Korbie, C Stirzaker, ... Clinical and Translational Medicine 12 (10), e1030, 2022 | 8 | 2022 |
Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor S Clark, E Zotenko, C Stirzaker, G Francis US Patent 11,352,672, 2022 | 6 | 2022 |
Epigenetic therapies and biomarkers in breast cancer LJ Brown, J Achinger-Kawecka, N Portman, S Clark, C Stirzaker, E Lim Cancers 14 (3), 474, 2022 | 24 | 2022 |
DNA Methylation Analysis of Circulating DNA Biomarkers K Warton, C Stirzaker, G Samimi, S Clark Cell-Free Circulating DNA: Purification and Analysis Techniques, 247-277, 2022 | | 2022 |
Identification of DNA methylation biomarkers with potential to predict response to neoadjuvant chemotherapy in triple-negative breast cancer B Meyer, S Clifton, W Locke, PL Luu, Q Du, D Lam, NJ Armstrong, ... Clinical Epigenetics 13, 1-7, 2021 | 17 | 2021 |
DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity Q Du, GC Smith, PL Luu, JM Ferguson, NJ Armstrong, CE Caldon, ... Cell Reports 36 (12), 2021 | 42 | 2021 |
MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detection PL Luu, PT Ong, TTH Loc, D Lam, R Pidsley, C Stirzaker, SJ Clark Bioinformatics 37 (15), 2198-2200, 2021 | 2 | 2021 |
Epigenetic changes during tumour development–functional epigenetics study C Stirzaker, K Skvortsova, SJ Clark Pathology 53, S10-S11, 2021 | | 2021 |
Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer J Achinger-Kawecka, C Stirzaker, N Portman, E Campbell, K Chia, Q Du, ... | 2 | 2021 |
Epigenetic therapy suppresses endocrine-resistant breast tumour growth by re-wiring ER-mediated 3D chromatin interactions J Achinger-Kawecka, C Stirzaker, KM Chia, N Portman, E Campbell, Q Du, ... bioRxiv, 2021.06. 21.449340, 2021 | 6 | 2021 |
Ubiquitin chromatin remodelling after DNA damage is associated with the expression of key cancer genes and pathways AJ Cole, KA Dickson, C Liddle, C Stirzaker, JS Shah, R Clifton-Bligh, ... Cellular and Molecular Life Sciences 78, 1011-1027, 2021 | 12 | 2021 |
Evaluation and measurement of epigenetic modifications in population-based studies C Stirzaker, NJ Armstrong Twin and Family Studies of Epigenetics, 17-39, 2021 | 2 | 2021 |
Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels D Lam, PL Luu, JZ Song, W Qu, GP Risbridger, MG Lawrence, J Lu, ... Clinical Epigenetics 12, 1-16, 2020 | 23 | 2020 |
Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer MG Lawrence, R Pidsley, B Niranjan, M Papargiris, BA Pereira, ... Clinical epigenetics 12, 1-18, 2020 | 24 | 2020 |
DNA methylation is required to maintain DNA replication timing precision and 3D genome integrity Q Du, GC Smith, PL Luu, JM Ferguson, NJ Armstrong, CE Caldon, ... Biorxiv, 2020.10. 15.338855, 2020 | 3 | 2020 |