287-OR: Traf6 Directs a Noncanonical Role for Innate Immune Signaling in Pancreatic ß-Cells E LEVI D ANCONA, JIE ZHU, EM WALKER, V SIDARALA, ... Diabetes 73 (Supplement_1), 2024 | | 2024 |
LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes J Li, J Zhu, Y Deng, EC Reck, EM Walker, V Sidarala, DL Hubers, ... bioRxiv, 2024 | | 2024 |
Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis A Arunagiri, M Alam, L Haataja, H Draz, B Alasad, P Samy, N Sadique, ... Protein Science 33 (4), e4949, 2024 | | 2024 |
Assessment of Mitophagy Flux in Pancreatic β-Cells Using Effective and Robust Complementary Approaches (Video)| JoVE E Levi-D’Ancona, V Sidarala, SA Soleimanpour JoVE (Journal of Visualized Experiments), e65789, 2023 | | 2023 |
Ovarian Cancer Patient-Derived Organoid Models for Pre-Clinical Drug Testing BE Fashemi, L van Biljon, J Rodriguez, O Graham, M Mullen, D Khabele JoVE (Journal of Visualized Experiments), e65068, 2023 | 2 | 2023 |
Complementary Approaches to Interrogate Mitophagy Flux in Pancreatic β-Cells E Levi-D’Ancona, V Sidarala, SA Soleimanpour Journal of visualized experiments: JoVE, 2023 | 1 | 2023 |
Mitochondrial metabolism and dynamics in pancreatic beta cell glucose sensing GA Rutter, V Sidarala, BA Kaufman, SA Soleimanpour Biochemical Journal 480 (11), 773-789, 2023 | 12 | 2023 |
Reciprocal regulatory balance within the CLEC16A–RNF41 mitophagy complex depends on an intrinsically disordered protein region MA Gingerich, J Zhu, B Chai, MP Vincent, N Xie, V Sidarala, NA Kotov, ... Journal of Biological Chemistry 299 (4), 2023 | 4 | 2023 |
An intrinsically disordered protein region encoded by the human disease gene CLEC16A regulates mitophagy MA Gingerich, X Liu, B Chai, GL Pearson, MP Vincent, T Stromer, J Zhu, ... Autophagy 19 (2), 525-543, 2023 | 6 | 2023 |
β-Cell Cre Expression and Reduced Ins1 Gene Dosage Protect Mice From Type 1 Diabetes S Skovsø, P Overby, J Memar-Zadeh, JTC Lee, JCC Yang, I Shanina, ... Endocrinology 163 (11), bqac144, 2022 | 7 | 2022 |
Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues GL Pearson, EM Walker, N Lawlor, A Lietzke, V Sidarala, J Zhu, T Stromer, ... bioRxiv, 2022.08. 02.502357, 2022 | | 2022 |
Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis V Sidarala, J Zhu, E Levi-D’Ancona, GL Pearson, EC Reck, EM Walker, ... Nature communications 13 (1), 2340, 2022 | 42 | 2022 |
Effects of pro-inflammatory cytokines on the pancreatic islet transcriptome: a view at both temporal and single-cell resolution V Sidarala, SA Soleimanpour Function 3 (3), zqac026, 2022 | | 2022 |
Mitofusin 1 and 2 regulation of mtDNA content is a critical determinant of glucose homeostasis V Sidarala, J Zhu, G Pearson, E Reck, B Kaufman, S Soleimanpour | 3* | 2021 |
Mitophagy protects β cells from inflammatory damage in diabetes V Sidarala, GL Pearson, VS Parekh, B Thompson, L Christen, ... JCI insight 5 (24), 2020 | 79 | 2020 |
52-OR: Mitophagy Forms a Protective Response to Inflammatory Damage in Pancreatic ß-Cells V Sidarala, S Soleimanpour Diabetes 69 (Supplement_1), 2020 | | 2020 |
Clarifying the function of genes at the chromosome 16p13 locus in type 1 diabetes: CLEC16A and DEXI MA Gingerich, V Sidarala, SA Soleimanpour Genes & Immunity 21 (2), 79-82, 2020 | 11 | 2020 |
Exposure to chronic hyperglycemic conditions results in Ras-related C3 botulinum toxin substrate 1 (Rac1)-mediated activation of p53 and ATM kinase in pancreatic β-cells V Sidarala, A Kowluru Apoptosis 22, 597-607, 2017 | 25 | 2017 |
The regulatory roles of mitogen-activated protein kinase (MAPK) pathways in health and diabetes: lessons learned from the pancreatic β-cell V Sidarala, A Kowluru Recent patents on endocrine, metabolic & immune drug discovery 10 (2), 76-84, 2016 | 69 | 2016 |
NSC23766, a known inhibitor of Tiam1-Rac1 signaling module, prevents the onset of type 1 diabetes in the NOD mouse model R Veluthakal, V Sidarala, A Kowluru Cellular Physiology and Biochemistry 39 (2), 760-767, 2016 | 38 | 2016 |