| Retinal proteome associated with bradykinin-induced edema N Murugesan, W Fickweiler, AC Clermont, Q Zhou, EP Feener Experimental eye research 186, 107744, 2019 | 7 | 2019 |
| Rapid and nearly complete suppression of plasma kallikrein activity with the oral inhibitor KVD900: Results of a phase 1 study evaluating KVD900's potential as a treatment for … A Maetzel, MD Smith, RM Morten, SL Hampton, GM De Donatis, ... ALLERGY 74, 271-272, 2019 | | 2019 |
| Complement C3 mediates vascular endothelial growth factor (VEGF) induced retinal edema but not visual dysfunction in mice. AC Clermont, A Feener, N Murugesan, LP Aiello, E Feener Investigative Ophthalmology & Visual Science 60 (9), 2791-2791, 2019 | | 2019 |
| Novel oral plasma kallikrein (PKa) inhibitors KV998052 and KV998054 ameliorate VEGF-induced retinal thickening in a murine model of retinal edema N Murugesan, AC Clermont, SJ Pethen, L Li, EJ Duckworth, SL Hampton, ... Investigative Ophthalmology & Visual Science 60 (9), 2596-2596, 2019 | 1 | 2019 |
| KVD900 as a Single Dose, Rapid, Oral Plasma Kallikrein Inhibitor for the On-Demand Treatment of Hereditary Angioedema Attacks: Pharmacokinetic and Pharmacodynamic results from … SL Hampton, GM De Donatis, NI Murugesan, LJ Rushbrooke, L Li, ... Journal of Allergy and Clinical Immunology 143 (2), AB39, 2019 | 6 | 2019 |
| Vascular endothelial growth factor (VEGF) mediates electroretinogram (ERG) dysfunction in mice through plasma kallikrein and nitric oxide AC Clermont, F Simao, N Murugesan, P Huang, LP Aiello, EP Feener Investigative Ophthalmology & Visual Science 59 (9), 3463-3463, 2018 | 1 | 2018 |
| A novel oral plasma kallikrein (PKal) inhibitor KV123833 blocks VEGF-mediated retinal vascular hyperpermeability in a murine model of retinal edema (# 3464) N Murugesan, AC Clermont, LJ Rushbrooke, PA Robson, ... | 5 | 2018 |
| KVD900 protects high molecular weight kininogen (HK) from ex vivo plasma kallikrein mediated cleavage in plasma from patients with hereditary angioedema (HAE): Results from a … EP Feener, N Murugesan, PA Robson, L Li, LJ Rushbrooke, R Thoonen, ... EAACI, 2018 | 1 | 2018 |
| Effects of Vascular endothelial growth factor (VEGF) on electroretinogram (ERG) amplitude in rats are mediated by bradykinin. AC Clermont, N Murugesan, T Ustunkaya, B Mastromarino, LP Aiello, ... Investigative Ophthalmology & Visual Science 58 (8), 5347-5347, 2017 | | 2017 |
| Increased FXII activity in vitreous of patients with Diabetic Macular Edema (DME) and in animal models of VEGF-and bradykinin-induced retinal edema T Ustunkaya, N Murugesan, AC Clermont, EP Feener Investigative Ophthalmology & Visual Science 57 (12), 4183-4183, 2016 | | 2016 |
| Complement component 3 (C3) is increased in vitreous in diabetic macular edema and is required for bradykinin (BK)-induced retinal edema. N Murugesan, AC Clermont, T Kita, EP Feener Investigative Ophthalmology & Visual Science 57 (12), 2016 | | 2016 |
| Vascular endothelial growth factor (VEGF) and bradykinin induce increased electroretinogram amplitude and decreased visual acuity. AC Clermont, N Murugesan, C Lin, SR Sheskey, DA Antonetti, EP Feener Investigative Ophthalmology & Visual Science 57 (12), 2016 | | 2016 |
| Plasma Kallikrein Mediates Vascular Endothelial Growth Factor–Induced Retinal Dysfunction and Thickening A Clermont, N Murugesan, Q Zhou, T Kita, PA Robson, LJ Rushbrooke, ... Investigative ophthalmology & visual science 57 (6), 2390-2399, 2016 | 32 | 2016 |
| Plasma kallikrein-kinin system as a VEGF-independent mediator of diabetic macular edema T Kita, AC Clermont, N Murugesan, Q Zhou, K Fujisawa, T Ishibashi, ... Diabetes 64 (10), 3588-3599, 2015 | 82 | 2015 |
| Thrombosis and hemorrhage in diabetic retinopathy: a perspective from an inflammatory standpoint N Murugesan, T Üstunkaya, EP Feener Seminars in thrombosis and hemostasis 41 (06), 659-664, 2015 | 39 | 2015 |
| Proteomic characterization of retinal edema in rats N Murugesan, AC Clermont, LL Sun, EP Feener Investigative Ophthalmology & Visual Science 56 (7), 4693-4693, 2015 | | 2015 |
| Vascular endothelial growth factor (VEGF)-and the kallikrein kinin system (KKS)-induced neuronal dysfunction in a rodent model of retinal edema. AC Clermont, N Murugesan, EP Feener Investigative Ophthalmology & Visual Science 56 (7), 5487-5487, 2015 | | 2015 |
| Plasma kallikrein (PKal) deficiency ameliorates the effects of vascular endothelial growth factor (VEGF) on retinal hyperpermeability and edema. AC Clermont, Q Zhou, N Murugesan, W Fickweiler, EP Feener Investigative Ophthalmology & Visual Science 55 (13), 594-594, 2014 | 1 | 2014 |
| Role of Akt in VEGF-, bradykinin-, and diabetes-induced retinal dysfunction and edema W Fickweiler, AC Clermont, N Murugesan, EP Feener Investigative Ophthalmology & Visual Science 55 (13), 2256-2256, 2014 | | 2014 |
| Active induction of experimental autoimmune encephalomyelitis by MOG 35-55 peptide immunization is associated with differential responses in separate compartments of the … N Murugesan, D Paul, Y Lemire, B Shrestha, S Ge, JS Pachter Fluids and Barriers of the CNS 9 (1), 15, 2012 | 54 | 2012 |
