Exploring nutrient supplementation and bioprocess optimization to improve the production of lentiviral vectors in serum‐free medium suspension cultures TA Vaz, AF Rodrigues, AS Coroadinha Biotechnology Journal 19 (1), 2300212, 2024 | 2 | 2024 |
Novel scFv against notch ligand JAG1 suitable for development of cell therapies toward JAG1-positive tumors G Silva, AF Rodrigues, S Ferreira, C Matos, RP Eleutério, G Marques, ... Biomolecules 13 (3), 459, 2023 | 2 | 2023 |
Novel scFv against Notch Ligand JAG1 Suitable for Development of Cell Therapies toward JAG1-Positive Tumors. Biomolecules 2023, 13, 459 G Silva, AF Rodrigues, S Ferreira, C Matos, RP Eleutério, G Marques, ... | | 2023 |
Modified envelope glycoproteins for retroviridae viral vector pseudotyping and process for obtaining it HA TOMÁS, DAF MESTRE, AFDEAF RODRIGUES, ... US Patent App. 17/612,057, 2022 | | 2022 |
Bioengineered liver cell models of hepatotropic infections F Arez, AF Rodrigues, C Brito, PM Alves Viruses 13 (5), 773, 2021 | 6 | 2021 |
Overexpression of ER protein processing and apoptosis regulator genes in human embryonic kidney 293 cells improves gene therapy vectors production AS Formas‐Oliveira, JS Basílio, AF Rodrigues, AS Coroadinha Biotechnology Journal 15 (9), 1900562, 2020 | 15 | 2020 |
Cell bank origin of MDCK parental cells shapes adaptation to serum-free suspension culture and canine adenoviral vector production AF Rodrigues, P Fernandes, T Laske, R Castro, PM Alves, Y Genzel, ... International Journal of Molecular Sciences 21 (17), 6111, 2020 | 6 | 2020 |
Improved GaLV-TR glycoproteins to pseudotype lentiviral vectors: impact of viral protease activity in the production of LV pseudotypes HA Tomás, DA Mestre, AF Rodrigues, MR Guerreiro, MJT Carrondo, ... Molecular Therapy Methods & Clinical Development 15, 1-8, 2019 | 21 | 2019 |
Year-long rhinovirus infection is influenced by atmospheric conditions, outdoor air virus presence, and immune system-related genetic polymorphisms AF Rodrigues, AM Santos, AM Ferreira, R Marino, ME Barreira, ... Food and environmental virology 11 (4), 340-349, 2019 | 26 | 2019 |
MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1 N Schmolka, PH Papotto, PV Romero, T Amado, FJ Enguita, A Amorim, ... Science immunology 3 (23), eaao1392, 2018 | 43 | 2018 |
LentiPro26: novel stable cell lines for constitutive lentiviral vector production HA Tomás, AF Rodrigues, MJT Carrondo, AS Coroadinha Scientific reports 8 (1), 5271, 2018 | 58 | 2018 |
Tetraspanins displayed in retrovirus-derived virus-like particles and their immunogenicity HR Soares, R Castro, HA Tomás, AF Rodrigues, P Gomes-Alves, B Bellier, ... Vaccine 34 (13), 1634-1641, 2016 | 17 | 2016 |
Increased titer and reduced lactate accumulation in recombinant retrovirus production through the down‐regulation of HIF1 and PDK AF Rodrigues, MR Guerreiro, AS Formas‐Oliveira, P Fernandes, ... Biotechnology and bioengineering 113 (1), 150-162, 2016 | 16 | 2016 |
Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology AF Rodrigues, HR Soares, MR Guerreiro, PM Alves, AS Coroadinha Biotechnology journal 10 (9), 1329-1344, 2015 | 88 | 2015 |
Single-step cloning-screening method: a new tool for developing and studying high-titer viral vector producer cells AF Rodrigues, AS Formas-Oliveira, MR Guerreiro, HA Tomás, PM Alves, ... Gene Therapy 22 (9), 685-695, 2015 | 12 | 2015 |
Robust expansion of human pluripotent stem cells: integration of bioprocess design with transcriptomic and metabolomic characterization MM Silva, AF Rodrigues, C Correia, MFQ Sousa, C Brito, AS Coroadinha, ... Stem cells translational medicine 4 (7), 731-742, 2015 | 45 | 2015 |
Cellular targets for improved manufacturing of virus-based biopharmaceuticals in animal cells AF Rodrigues, MJT Carrondo, PM Alves, AS Coroadinha Trends in biotechnology 32 (12), 602-607, 2014 | 32 | 2014 |
Metabolic pathways recruited in the production of a recombinant enveloped virus: Mining targets for process and cell engineering AF Rodrigues, AS Formas-Oliveira, VS Bandeira, PM Alves, WS Hu, ... Metabolic Engineering 20, 131-145, 2013 | 37 | 2013 |
Impact of E1 and Cre on adenovirus vector amplification: developing MDCK CAV-2-E1 and E1-Cre transcomplementing cell lines P Fernandes, VM Santiago, AF Rodrigues, H Tomas, EJ Kremer, ... PLoS One 8 (4), e60342, 2013 | 21 | 2013 |
Lentiviral gene therapy vectors: challenges and future directions HA Tomás, AF Rodrigues, PM Alves, AS Coroadinha Gene therapy-tools and potential applications, 2013 | 40 | 2013 |