| Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy M Zuckermann, C He, J Andrews, A Bagchi, R Sloan-Henry, B Bianski, ... Molecular cancer 23 (1), 123, 2024 | | 2024 |
| Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts X Lin, D Gupta, A Vaitsiankova, SK Bhandari, KSK Leung, D Menolfi, ... bioRxiv, 2024.03. 12.584665, 2024 | 1 | 2024 |
| Next‐generation bromodomain inhibitors of the SWI/SNF complex enhance DNA damage and cell death in glioblastoma C Yang, Y He, Y Wang, PJ McKinnon, V Shahani, DD Miller, LM Pfeffer Journal of Cellular and Molecular Medicine 27 (18), 2770-2781, 2023 | 4 | 2023 |
| Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers high‐grade gliomas DE Reuss, SM Downing, CV Camacho, YD Wang, RM Piro, ... Neuropathology and Applied Neurobiology 49 (4), e12915, 2023 | 3 | 2023 |
| Genome integrity and inflammation in the nervous system PJ McKinnon DNA repair 119, 103406, 2022 | 7 | 2022 |
| Out of LINE: Transposons, genome integrity, and neurodegeneration LC Dumitrache, PJ McKinnon Neuron 110 (20), 3217-3219, 2022 | 2 | 2022 |
| MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma M Zuckermann, C He, J Andrews, R Sloan-Henry, B Bianski, J Xie, ... Neuro-Oncology 24 (Supplement_1), i169-i169, 2022 | 2 | 2022 |
| Ptch2 is a Potential Regulator of Mesenchymal Stem Cells. Front. Physiol. 13: 877565. doi: 10.3389/fphys. 2022.877565 E Juuri, P Tikka, A Domanskyi, I Corfe, W Morita, PJ Mckinnon, N Jandova, ... Frontiers in Physiology| www. frontiersin. org 13, 2022 | | 2022 |
| Ptch2 is a potential regulator of mesenchymal stem cells E Juuri, P Tikka, A Domanskyi, I Corfe, W Morita, PJ Mckinnon, N Jandova, ... Frontiers in Physiology 13, 877565, 2022 | 3 | 2022 |
| Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage–induced neurodegeneration YD Kwak, TI Shaw, SM Downing, A Tewari, Aditi, H Jin, Y Li, ... Science Advances 7 (51), eabg6363, 2021 | 22 | 2021 |
| Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair SM Downing, PA Schreiner, YD Kwak, Y Li, TI Shaw, HR Russell, ... Neuron 109 (24), 3962-3979. e6, 2021 | 25 | 2021 |
| A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation H Perez, MF Abdallah, JI Chavira, AS Norris, MT Egeland, KL Vo, ... Elife 10, e64695, 2021 | 16 | 2021 |
| The dystonia gene THAP1 controls DNA double-strand break repair choice K Shinoda, D Zong, E Callen, W Wu, LC Dumitrache, F Belinky, R Chari, ... Molecular cell 81 (12), 2611-2624. e10, 2021 | 18 | 2021 |
| Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures E Komulainen, J Badman, S Rey, S Rulten, L Ju, K Fennell, I Kalasova, ... EMBO reports 22 (5), e51851, 2021 | 13 | 2021 |
| The cancer-associated ATM R3008H mutation reveals the link between ATM activation and its exchange M Milanovic, LM Houghton, D Menolfi, JH Lee, K Yamamoto, Y Li, BJ Lee, ... Cancer research 81 (2), 426-437, 2021 | 7 | 2021 |
| RAD51-Mediated DNA Homologous Recombination Is Independent of PTEN Mutational Status A Sinha, A Saleh, R Endersby, SH Yuan, CR Chokshi, KR Brown, B Kuzio, ... Cancers 12 (11), 3178, 2020 | 12 | 2020 |
| 53BP1 enforces distinct pre-and post-resection blocks on homologous recombination E Callen, D Zong, W Wu, N Wong, A Stanlie, M Ishikawa, R Pavani, ... Molecular cell 77 (1), 26-38. e7, 2020 | 108 | 2020 |
| Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance DR McNeill, AM Whitaker, WJ Stark, JL Illuzzi, PJ McKinnon, ... Mutagenesis 35 (1), 27-38, 2020 | 51 | 2020 |
| Functionally distinctive Ptch receptors establish multimodal Hedgehog signaling in the tooth epithelial stem cell niche M Binder, P Chmielarz, PJ Mckinnon, LC Biggs, I Thesleff, A Balic Stem Cells 37 (9), 1238-1248, 2019 | 24 | 2019 |
| Abstract LB-289: Genomic instability and the development of high-grade gliomas LJ Pribyl, SM Downing, CV Camacho, JD Larson, SJ Baker, PJ McKinnon Cancer Research 79 (13_Supplement), LB-289-LB-289, 2019 | | 2019 |
