关注
Mario Moscarello
标题
引用次数
年份
Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof
L Kotra, M Moscarello
US Patent 9,908,853, 2018
12018
Protein hypercitrullination in CNS demyelinating disease reversed by PAD inhibition
MA Moscarello
Protein deimination in human health and disease, 187-217, 2014
12014
The modulation of glycosyltransferase activity in Golgi membranes
MR Pâquet, MA Moscarello
Membrane Fluidity in Biology: Cellular Aspects, 209, 2013
12013
Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis
MA Moscarello, H Lei, FG Mastronardi, S Winer, H Tsui, Z Li, C Ackerley, ...
Disease models & mechanisms 6 (2), 467-478, 2013
1122013
Novel inhibitors of protein arginine deiminase with potential activity in multiple sclerosis animal model
L Wei, E Wasilewski, SK Chakka, AM Bello, MA Moscarello, LP Kotra
Journal of medicinal chemistry 56 (4), 1715-1722, 2013
652013
Interrogation of the active sites of protein arginine deiminases (PAD1,-2, and-4) using designer probes
AM Bello, E Wasilewski, L Wei, MA Moscarello, LP Kotra
ACS Medicinal Chemistry Letters 4 (2), 249-253, 2013
162013
Myelin basic protein undergoes a broader range of modifications in mammals than in lower vertebrates
C Zhang, AK Walker, R Zand, MA Moscarello, JM Yan, PC Andrews
Journal of proteome research 11 (10), 4791-4802, 2012
382012
isease Models & Mechanisms DMM
MA Moscarello, H Lei, FG Mastronardi, S Winer, H Tsui, Z Li, C Ackerley, ...
2012
Anti-myelin antibodies modulate clinical expression of childhood multiple sclerosis
KC O'Connor, C Lopez-Amaya, D Gagne, L Lovato, NH Moore-Odom, ...
Journal of neuroimmunology 223 (1-2), 92-99, 2010
732010
NMDA receptor encephalitis mimicking seronegative neuromyelitis optica
MC Kruer, TK Koch, DN Bourdette, D Chabas, E Waubant, S Mueller, ...
Neurology 74 (18), 1473-1475, 2010
1052010
Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system
AA Musse, Z Li, CA Ackerley, D Bienzle, H Lei, R Poma, G Harauz, ...
Disease models & mechanisms 1 (4-5), 229-240, 2008
1572008
Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities
DD Wood, CA Ackerley, B Van Den Brand, L Zhang, R Raijmakers, ...
Laboratory investigation 88 (4), 354-364, 2008
1362008
Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated
FG Mastronardi, A Noor, DD Wood, T Paton, MA Moscarello
Journal of neuroscience research 85 (9), 2006-2016, 2007
2292007
Synergy between paclitaxel plus an exogenous methyl donor in the suppression of murine demyelinating diseases
FG Mastronardi, H Tsui, S Winer, DD Wood, T Selvanantham, C Galligan, ...
Multiple Sclerosis Journal 13 (5), 596-609, 2007
302007
The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis
MA Moscarello, FG Mastronardi, DD Wood
Neurochemical research 32, 251-256, 2007
3022007
Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 …
FG Mastronardi, DD Wood, J Mei, R Raijmakers, V Tseveleki, HM Dosch, ...
Journal of Neuroscience 26 (44), 11387-11396, 2006
2832006
Differences in susceptibility of MBP charge isomers to digestion by stromelysin-1 (MMP-3) and release of an immunodominant epitope
CA D’Souza, MA Moscarello
Neurochemical research 31, 1045-1054, 2006
742006
Increased citrullination of histone H3 in MS brain and animal models of demyelination: A role for TNF-induced PAD4 translocation
FG Mastronardi, DD Wood, J Mei, R Raijmakers, V Tseveleki, HM Dosch, ...
32006
Autocatalytic cleavage of myelin basic protein: an alternative to molecular mimicry
CA D'Souza, DD Wood, YM She, MA Moscarello
Biochemistry 44 (38), 12905-12913, 2005
572005
Molecules affecting myelin stability: a novel hypothesis regarding the pathogenesis of multiple sclerosis
FG Mastronardi, MA Moscarello
Journal of neuroscience research 80 (3), 301-308, 2005
1072005
系统目前无法执行此操作,请稍后再试。
文章 1–20