Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof L Kotra, M Moscarello US Patent 9,908,853, 2018 | 1 | 2018 |
Protein hypercitrullination in CNS demyelinating disease reversed by PAD inhibition MA Moscarello Protein deimination in human health and disease, 187-217, 2014 | 1 | 2014 |
The modulation of glycosyltransferase activity in Golgi membranes MR Pâquet, MA Moscarello Membrane Fluidity in Biology: Cellular Aspects, 209, 2013 | 1 | 2013 |
Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis MA Moscarello, H Lei, FG Mastronardi, S Winer, H Tsui, Z Li, C Ackerley, ... Disease models & mechanisms 6 (2), 467-478, 2013 | 112 | 2013 |
Novel inhibitors of protein arginine deiminase with potential activity in multiple sclerosis animal model L Wei, E Wasilewski, SK Chakka, AM Bello, MA Moscarello, LP Kotra Journal of medicinal chemistry 56 (4), 1715-1722, 2013 | 65 | 2013 |
Interrogation of the active sites of protein arginine deiminases (PAD1,-2, and-4) using designer probes AM Bello, E Wasilewski, L Wei, MA Moscarello, LP Kotra ACS Medicinal Chemistry Letters 4 (2), 249-253, 2013 | 16 | 2013 |
Myelin basic protein undergoes a broader range of modifications in mammals than in lower vertebrates C Zhang, AK Walker, R Zand, MA Moscarello, JM Yan, PC Andrews Journal of proteome research 11 (10), 4791-4802, 2012 | 38 | 2012 |
isease Models & Mechanisms DMM MA Moscarello, H Lei, FG Mastronardi, S Winer, H Tsui, Z Li, C Ackerley, ... | | 2012 |
Anti-myelin antibodies modulate clinical expression of childhood multiple sclerosis KC O'Connor, C Lopez-Amaya, D Gagne, L Lovato, NH Moore-Odom, ... Journal of neuroimmunology 223 (1-2), 92-99, 2010 | 73 | 2010 |
NMDA receptor encephalitis mimicking seronegative neuromyelitis optica MC Kruer, TK Koch, DN Bourdette, D Chabas, E Waubant, S Mueller, ... Neurology 74 (18), 1473-1475, 2010 | 105 | 2010 |
Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system AA Musse, Z Li, CA Ackerley, D Bienzle, H Lei, R Poma, G Harauz, ... Disease models & mechanisms 1 (4-5), 229-240, 2008 | 157 | 2008 |
Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities DD Wood, CA Ackerley, B Van Den Brand, L Zhang, R Raijmakers, ... Laboratory investigation 88 (4), 354-364, 2008 | 136 | 2008 |
Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated FG Mastronardi, A Noor, DD Wood, T Paton, MA Moscarello Journal of neuroscience research 85 (9), 2006-2016, 2007 | 229 | 2007 |
Synergy between paclitaxel plus an exogenous methyl donor in the suppression of murine demyelinating diseases FG Mastronardi, H Tsui, S Winer, DD Wood, T Selvanantham, C Galligan, ... Multiple Sclerosis Journal 13 (5), 596-609, 2007 | 30 | 2007 |
The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis MA Moscarello, FG Mastronardi, DD Wood Neurochemical research 32, 251-256, 2007 | 302 | 2007 |
Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 … FG Mastronardi, DD Wood, J Mei, R Raijmakers, V Tseveleki, HM Dosch, ... Journal of Neuroscience 26 (44), 11387-11396, 2006 | 283 | 2006 |
Differences in susceptibility of MBP charge isomers to digestion by stromelysin-1 (MMP-3) and release of an immunodominant epitope CA D’Souza, MA Moscarello Neurochemical research 31, 1045-1054, 2006 | 74 | 2006 |
Increased citrullination of histone H3 in MS brain and animal models of demyelination: A role for TNF-induced PAD4 translocation FG Mastronardi, DD Wood, J Mei, R Raijmakers, V Tseveleki, HM Dosch, ... | 3 | 2006 |
Autocatalytic cleavage of myelin basic protein: an alternative to molecular mimicry CA D'Souza, DD Wood, YM She, MA Moscarello Biochemistry 44 (38), 12905-12913, 2005 | 57 | 2005 |
Molecules affecting myelin stability: a novel hypothesis regarding the pathogenesis of multiple sclerosis FG Mastronardi, MA Moscarello Journal of neuroscience research 80 (3), 301-308, 2005 | 107 | 2005 |