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Jung-Eun Park
Jung-Eun Park
在 mail.nih.gov 的电子邮件经过验证
标题
引用次数
年份
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4+ T cells
JE Park, TS Kim, Y Zeng, M Mikolaj, J Il Ahn, MS Alam, CM Monnie, V Shi, ...
Nature Communications 15 (1), 2017, 2024
12024
Plk1 polo box domain inhibitors and method of treating cancer
KS Lee, KA Jacobson, CN Alverez, JE Park, P Oliva, H Lee, KP Kirsch
US Patent App. 18/028,463, 2023
2023
Specific inhibition of an anticancer target, polo-like kinase 1, by allosterically dismantling its mechanism of substrate recognition
JE Park, K Kirsch, H Lee, P Oliva, JI Ahn, H Ravishankar, Y Zeng, SD Fox, ...
Proceedings of the National Academy of Sciences 120 (35), e2305037120, 2023
12023
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr• VprBP• Plk4 complex in CD4+ T cells
K Lee, JE Park, TS Kim, Y Zeng, C Monnie, M Alam, M Zhou, M Mikolaj, ...
2023
Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells
J Il Ahn, L Zhang, H Ravishankar, L Fan, K Kirsch, Y Zeng, L Meng, ...
Communications Biology 6 (1), 712, 2023
12023
Structural optimization and anticancer activity of Polo-Like Kinase 1 (Plk1) polo-box domain (PBD) Inhibitors and their prodrugs
JE Park, H Lee, P Oliva, K Kirsch, B Kim, JI Ahn, CN Alverez, S Gaikwad, ...
ACS Pharmacology & Translational Science 6 (3), 422-446, 2023
22023
Author Correction: Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells
JI Ahn, L Zhang, H Ravishankar, L Fan, K Kirsch, Y Zeng, L Meng, JE Park, ...
Communications Biology 6, 2023
2023
Self‐assembling Long Coiled‐coil Proteins Driving the Formation of a Nanoscale Cylindrical Architecture at Human Centrosomes
JI Ahn, H Ravishankar, KP Kirsch, JE Park, KS Lee
The FASEB Journal 36, 2022
2022
Novel macrocyclic peptidomimetics targeting the polo-box domain of polo-like kinase 1
SS Ryu, JE Park, YJ Ham, DC Lim, NP Kwiatkowski, DH Kim, D Bhunia, ...
Journal of medicinal chemistry 65 (3), 1915-1932, 2022
52022
Constructing PCM with architecturally distinct higher-order assemblies
KS Lee, JE Park, J il Ahn, Y Zeng
Current Opinion in Structural Biology 66, 66-73, 2021
172021
Autophosphorylation-induced self-assembly and STIL-dependent reinforcement underlie Plk4’s ring-to-dot localization conversion around a human centriole
JE Park, L Meng, EK Ryu, K Nagashima, U Baxa, JK Bang, KS Lee
Cell Cycle 19 (24), 3419-3436, 2020
52020
Phase separation of the Cep63• Cep152 complex underlies the formation of dynamic supramolecular self-assemblies at human centrosomes
JI Ahn, JE Park, L Meng, L Zhang, TS Kim, MJ Kruhlak, BY Kim, KS Lee
Cell Cycle 19 (24), 3437-3457, 2020
142020
Identification of a new heterocyclic scaffold for inhibitors of the polo-box domain of polo-like kinase 1
CN Alverez, JE Park, KS Toti, Y Xia, KW Krausz, G Rai, JK Bang, ...
Journal of medicinal chemistry 63 (22), 14087-14117, 2020
162020
Development of a polo-like kinase-1 polo-box domain inhibitor as a tumor growth suppressor in mice models
P Gunasekaran, MS Yim, M Ahn, NK Soung, JE Park, J Kim, G Bang, ...
Journal of medicinal chemistry 63 (23), 14905-14920, 2020
182020
A self-assembled cylindrical platform for Plk4-induced centriole biogenesis
KS Lee, JE Park, J Il Ahn, Z Wei, L Zhang
Open Biology 10 (8), 200102, 2020
72020
Requirement of the Cep57-Cep63 interaction for proper Cep152 recruitment and centriole duplication
Z Wei, TS Kim, JI Ahn, L Meng, Y Chen, EK Ryu, B Ku, M Zhou, SJ Kim, ...
Molecular and cellular biology 40 (10), e00535-19, 2020
322020
Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis
JE Park, L Zhang, JK Bang, T Andresson, F DiMaio, KS Lee
Nature communications 10 (1), 4959, 2019
642019
Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
TR Burke Jr, F Liu, KS Lee, JE Park
US Patent 10,266,565, 2019
32019
Molecular architecture of a cylindrical self-assembly at human centrosomes
TS Kim, L Zhang, J Il Ahn, L Meng, Y Chen, E Lee, JK Bang, JM Lim, ...
Nature communications 10 (1), 1151, 2019
402019
Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use
W Qian, JE Park, CC Lai, JA Kelley, KS Lee, TR Burke Jr
US Patent 10,047,122, 2018
2018
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