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Zhijian Chen
Zhijian Chen
在 utsouthwestern.edu 的电子邮件经过验证
标题
引用次数
年份
Editorial overview: Four dimensions of innate immunity
D Bogunovic, ZJ Chen
Current Opinion in Immunology 75, 102174, 2022
2022
TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance
T Li, S Yum, M Li, X Chen, X Zuo, ZJ Chen
Journal of Experimental Medicine 219 (1), e20211539, 2021
332021
cGAS restricts colon cancer development by protecting intestinal barrier integrity
S Hu, Y Fang, X Chen, T Cheng, M Zhao, M Du, T Li, M Li, Z Zeng, Y Wei, ...
Proceedings of the National Academy of Sciences 118 (23), e2105747118, 2021
492021
TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections
S Yum, M Li, Y Fang, ZJ Chen
Proceedings of the National Academy of Sciences 118 (14), e2100225118, 2021
3182021
Phosphorylation and chromatin tethering prevent cGAS activation during mitosis
T Li, T Huang, M Du, X Chen, F Du, J Ren, ZJ Chen
Science 371 (6535), eabc5386, 2021
1682021
Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression
K Zhang, L Miorin, T Makio, I Dehghan, S Gao, Y Xie, H Zhong, M Esparza, ...
Science Advances 7 (6), eabe7386, 2021
1872021
MLH1 deficiency-triggered DNA hyperexcision by exonuclease 1 activates the cGAS-STING pathway
J Guan, C Lu, Q Jin, H Lu, X Chen, L Tian, Y Zhang, J Ortega, J Zhang, ...
Cancer cell 39 (1), 109-121. e5, 2021
1472021
cGAS suppresses genomic instability as a decelerator of replication forks
H Chen, H Chen, J Zhang, Y Wang, A Simoneau, H Yang, AS Levine, ...
Science advances 6 (42), eabb8941, 2020
962020
STEEP mediates STING ER exit and activation of signaling
B Zhang, R Nandakumar, LS Reinert, J Huang, A Laustsen, Z Gao, C Sun, ...
Nature immunology 21 (8), 868-879, 2020
1062020
Old dogs, new trick: classic cancer therapies activate cGAS
S Yum, M Li, ZJ Chen
Cell research 30 (8), 639-648, 2020
1392020
Structures and mechanisms in the cGAS-STING innate immunity pathway
X Zhang, X Bai, ZJ Chen
Immunity 53 (1), 43-53, 2020
4162020
Type I interferon response in radiation-induced anti-tumor immunity
F Zhang, S Manna, LM Pop, ZJ Chen, YX Fu, R Hannan
Seminars in radiation oncology 30 (2), 129-138, 2020
282020
–The Garibaldi Volcanic Belt Geothermal Energy Project–Mount Meager 2019 Field Program
SE Grasby, SM Ansari, R Bryant, A Calahorrano-DiPatre, Z Chen, ...
Garibaldi Geothermal Energy Project, 1, 2020
62020
Discovery of small-molecule cyclic GMP-AMP synthase inhibitors
R Padilla-Salinas, L Sun, R Anderson, X Yang, S Zhang, ZJ Chen, H Yin
The Journal of Organic Chemistry 85 (3), 1579-1600, 2019
602019
Structural basis of STING binding with and phosphorylation by TBK1
C Zhang, G Shang, X Gui, X Zhang, X Bai, ZJ Chen
Nature 567 (7748), 394-398, 2019
7192019
Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
X Gui, H Yang, T Li, X Tan, P Shi, M Li, F Du, ZJ Chen
Nature 567 (7747), 262-266, 2019
8922019
cGAS in action: Expanding roles in immunity and inflammation
A Ablasser, ZJ Chen
Science 363 (6431), eaat8657, 2019
7502019
Roles of the cGAS-STING pathway in cancer immunosurveillance and immunotherapy
S Yum, M Li, AE Frankel, ZJ Chen
Annual review of cancer biology 3 (1), 323-344, 2019
792019
Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
G Shang, C Zhang, ZJ Chen, X Bai, X Zhang
Nature 567 (7748), 389-393, 2019
5262019
PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation
J Chen, ZJ Chen
Nature 564 (7734), 71-76, 2018
5722018
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