O29 A core transcriptional resistome, characterised by neutrophil degranulation and extracellular matrix dysregulation, predicts resistance to multiple therapies in UC A Saifuddin, D Cozzetto, M Olbei, P Pavlidis, A Hart, T Korcsmaros, ... Gut 73 (Suppl 1), A16-A17, 2024 | | 2024 |
Tu1761 GENE CORRELATION NETWORK ANALYSES REVEAL TRANSCRIPT MODULES AND PATHOGENIC MECHANISMS ASSOCIATED WITH RESISTANCE AND RESPONSE TO USTEKINUMAB THERAPY IN ULCERATIVE COLITIS A Saifuddin, D Cozzetto, M Olbei, P Pavlidis, A Hart, T Korcsmaros, ... Gastroenterology 166 (5), S-1410, 2024 | | 2024 |
340 BEYOND ATG16L1: MULTIPLE NON-CODING SNPS PERTURB AUTOPHAGY AND STRATIFY IBD PATIENTS INTO DISTINCT SUBGROUPS L Csabai, D Modos, B Bohar, M Olbei, L Gul, J Thomas, B Verstockt, ... Gastroenterology 166 (5), S-78-S-79, 2024 | | 2024 |
Revolutionizing immune research with organoid-based co-culture and chip systems D Papp, T Korcsmaros, I Hautefort Clinical and Experimental Immunology, uxae004, 2024 | 2 | 2024 |
AutophagyNet: high-resolution data source for the analysis of autophagy and its regulation L Csabai, B Bohár, D Türei, S Prabhu, L Földvári-Nagy, M Madgwick, ... Autophagy 20 (1), 188-201, 2024 | 1 | 2024 |
DOP31 Gene correlation network analyses reveal transcript modules and pathogenic mechanisms associated with resistance and response to ustekinumab therapy in Ulcerative Colitis A Saifuddin, D Cozzetto, M Olbei, A Hart, T Korcsmaros, N Powell Journal of Crohn's and Colitis 18 (Supplement_1), i129-i129, 2024 | | 2024 |
Managing type 2 diabetes: targeting a microbial enzyme as a novel treatment option A Keller-Pintér, T Korcsmáros, T Vellai Signal Transduction and Targeted Therapy 8 (1), 444, 2023 | 1 | 2023 |
Sulforaphane rewires central metabolism to support antioxidant response and achieve glucose homeostasis F Bernuzzi, A Maertens, S Saha, P Troncoso-Rey, T Ludwig, K Hiller, ... Redox Biology 67, 102878, 2023 | 3 | 2023 |
Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on an IL23/IFNγ axis JW Lo, D Cozzetto, JL Alexander, NP Danckert, M Madgwick, N Knox, ... Nature Communications 14 (1), 6719, 2023 | | 2023 |
Genetic signature detected in T cell receptors from patients with severe COVID-19 M Corpas, C de Mendoza, V Moreno-Torres, I Pintos, P Seoane, ... Iscience 26 (10), 2023 | 1 | 2023 |
Democratizing knowledge representation with BioCypher S Lobentanzer, P Aloy, J Baumbach, B Bohar, VJ Carey, P Charoentong, ... Nature Biotechnology 41 (8), 1056-1059, 2023 | 23 | 2023 |
Stress-responsive Gdf15 counteracts renointestinal toxicity via autophagic and microbiota reprogramming N Ray, SJ Park, H Jung, J Kim, T Korcsmaros, Y Moon Communications Biology 6 (1), 602, 2023 | 1 | 2023 |
Sa1795 SYSTEMS GENOMICS AND NETWORK APPROACHES UNCOVER HOW SINGLE NUCLEOTIDE POLYMORPHISMS IN CROHN'S DISEASE AND ULCERATIVE COLITIS AFFECT COMMON PROCESSES THROUGH DIFFERENT … D Modos, M Poletti, J Brooks-Warburton, B Bohar, M Madgwick, ... Gastroenterology 164 (6), S-435, 2023 | | 2023 |
Oscillation of autophagy induction under cellular stress and what lies behind it, a systems biology study B Hajdú, L Csabai, M Márton, M Holczer, T Korcsmáros, O Kapuy International Journal of Molecular Sciences 24 (8), 7671, 2023 | 4 | 2023 |
Microbiota-dependent expression of CTLA-4 by innate lymphoid cells restrains IFNγ dependent colitis J Lo, JH Schroeder, G Beattie, L Roberts, D Cozzetto, O Omer, E Ross, ... | | 2023 |
Various regulatory single nucleotide polymorphisms regulate similar biological pathways in Crohn's disease D Modos, M Poletti, J Brooks-Warburton, B Bohar, M Madgwick, ... Journal Of Crohns & Colitis 17, I260-I261, 2023 | | 2023 |
DOP71 TREM1, OSM and a co-expressed transcriptional module are core components of the molecular resistome to anti-cytokine therapy in Ulcerative Colitis A Saifuddin, M Madgwick, D Cozzetto, P Pavlidis, B Verstockt, A Hart, ... Journal of Crohn's and Colitis 17 (Supplement_1), i146-i148, 2023 | | 2023 |
The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients JL Alexander, BH Mullish, NP Danckert, Z Liu, ML Olbei, A Saifuddin, ... EBioMedicine 88, 2023 | 26 | 2023 |
FAK family proteins regulate in vivo breast cancer metastasis via distinct mechanisms. A Genna, J Alter, M Poletti, T Meirson, T Sneh, M Gendler, N Saleev, ... bioRxiv, 2023.10. 27.564212, 2023 | | 2023 |
Invariant natural killer T-cell and CD4+ T-cell derived IL22 is a regulator of epithelial-to-mesenchymal transition and extracellular matrix remodelling in perianal fistulas LE Constable, N Iqbal, D Cozzetto, L Csabai, S Anandabaskaran, ... bioRxiv, 2023.09. 11.557122, 2023 | | 2023 |