Abstract 2237 Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals sub-conductance that is abolished by PKA phosphorylation O Haji-Ghassemi, F Van Petegem, H Valdivia, S Chen, K Woll, G Gurrola, ... Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Research Note: Clostridium perfringens NetB and CnaA neutralizing nanobodies in feed reduce the incidence of poultry necrotic enteritis SA Loutet, S Cheung, S Zaytsoff, C Hofacre, MK Jones, F Van Petegem, ... Poultry Science, 103578, 2024 | | 2024 |
Cryo-EM analysis of the malignant hyperthermia-causing T4826I mutant of ryanodine receptor 1 and its interplay with pharmacological agents YS Chen, M García-Castañeda, PD Allen, F Van Petegem Biophysical Journal 123 (3), 443a, 2024 | | 2024 |
Propofol binding sites on ryanodine receptor 1 TT Joseph, W Bu, O Haji-Ghassemi, K Woll, GH Brannigan, ... Biophysical Journal 123 (3), 534a, 2024 | | 2024 |
Cryo-EM reveals binding of ryanodine receptors to drugs that are associated with muscle weakness S Molinarolo, CR Valdivia, HH Valdivia, F Van Petegem Biophysical Journal 123 (3), 534a, 2024 | | 2024 |
Localising elements in single-particle reconstructions by REEL-EM: Reconstructed Electron Energy-Loss-Elemental Mapping O Pfeil-Gardiner, HVD Rosa, D Riedel, YS Chen, D Lorks, P Kukelhan, ... bioRxiv, 2024.01. 18.575858, 2024 | | 2024 |
Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1) TT Joseph, W Bu, O Haji-Ghassemi, YS Chen, K Woll, PD Allen, ... bioRxiv, 2024.01. 10.575040, 2024 | | 2024 |
Crystallographic, kinetic, and calorimetric investigation of PKA interactions with L-type calcium channels and Rad GTPase R Yoo, O Haji-Ghassemi, C McFarlane, J Xu, F Van Petegem bioRxiv, 2023.10. 24.563811, 2023 | | 2023 |
RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET J Seflova, JA Schwarz, AN Smith, B Svensson, DJ Blackwell, TA Phillips, ... ACS Chemical Biology 18 (10), 2290-2299, 2023 | 2 | 2023 |
Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives S Cholak, JW Saville, X Zhu, AM Berezuk, KS Tuttle, O Haji-Ghassemi, ... Structure 31 (7), 790-800. e4, 2023 | 5 | 2023 |
Electrophysiological Characterisation of Calcium Channel Mutant, Cav1. 2-R1586Q, Associated With Long QT Syndrome 8 A Dyrda, E Ingley, F van Petegem, L Hool Heart, Lung and Circulation 32, S153-S154, 2023 | | 2023 |
Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation O Haji-Ghassemi, YS Chen, K Woll, GB Gurrola, CR Valdivia, W Cai, S Li, ... Science Advances 9 (21), eadf4936, 2023 | 5 | 2023 |
PO-01-178 MAPPING OF PATHOGENIC VARIANT HOTSPOTS ON THE STRUCTURE OF RYANODINE RECEPTOR TYPE 2 DRIVES A RATIONAL DRUG DESIGN APPROACH FOR CATECHOLAMINERGIC POLYMORPHIC … G Monaco, LM Kurzlechner, F Van Petegem, AP Landstrom Heart Rhythm 20 (5), S155, 2023 | | 2023 |
RNA Polymerase II transcription independent of TBP in murine embryonic stem cells JZJ Kwan, TF Nguyen, AC Uzozie, MA Budzynski, J Cui, JMC Lee, ... Elife 12, e83810, 2023 | 6 | 2023 |
Structural insights for the modulation of KCNQ1 channel by ML277 E Kyriakis, J Eldstrom, K Willegems, F Ataei, H Sahakyan, Y Dou, S Russo, ... Biophysical Journal 122 (3), 21a, 2023 | | 2023 |
Cryo-EM investigation of the subconductance state of ryanodine receptor calcium release channels induced by scorpion toxins F Van Petegem, O Haji-Ghassemi, Y Chen, K Woll, CR Valdivia, ... Biophysical Journal 122 (3), 164a, 2023 | | 2023 |
Investigation of PKA interactions with cardiac voltage gated calcium channel and Rad GTPase O Haji-Ghassemi, R Yoo, J Xu, C McFarlane, F Van Petegem Biophysical Journal 122 (3), 480a-481a, 2023 | | 2023 |
Allosteric Modulation of RyR1 with Nucleotide Analogs S Cholak, J Saville, X Zhu, A Berezuk, O Haji-Ghassemi, K Tuttle, ... PROTEIN SCIENCE 32, 2023 | | 2023 |
RYR-1-related diseases international research workshop: from mechanisms to treatments Pittsburgh, PA, USA, 21-22 July 2022 TN O'Connor, LR van den Bersselaar, YS Chen, S Nicolau, B Simon, ... | 3 | 2023 |
Structural and functional conservation of the activating Ca2+ binding site in inositol 1, 4.5-trisphosphate and ryanodine receptors YS Chen, F Van Petegem Cell Calcium 108, 102671, 2022 | 2 | 2022 |