Overcoming the cell membrane to target intracellular oncoproteins CJ Brown, Y Li, K Sabapathy Frontiers in Oncology 13, 1222095, 2023 | | 2023 |
Further Characterization of Fungal Halogenase RadH and Its Homologs GR Peh, GA Gunawan, T Tay, E Tiong, LL Tan, S Jiang, YL Goh, S Ye, ... Biomolecules 13 (7), 1081, 2023 | 1 | 2023 |
A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays SH Kasper, S Otten, B Squadroni, C Orr‐Terry, Y Kuang, L Mussallem, ... Bioengineering & Translational Medicine, e10542, 2023 | | 2023 |
Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists A Chandramohan, H Josien, T Yuen, R Duggal, D Spiegelberg, L Yan, ... bioRxiv, 2023.02. 25.530030, 2023 | 1 | 2023 |
Stitched peptides as potential cell permeable inhibitors of oncogenic DAXX protein C Jelinska, S Kannan, Y Frosi, SR Ramlan, F Winnerdy, ... bioRxiv, 2022.09. 25.508451, 2022 | 1 | 2022 |
P53 activator peptidomimetic macrocycles P Aronica, CJ Brown, FJ Ferrer, CW Johannes, S Kannan, DP Lane, ... US Patent App. 17/618,751, 2022 | | 2022 |
Engineering an autonomous VH domain to modulate intracellular pathways and to interrogate the eIF4F complex Y Frosi, YC Lin, J Shimin, SR Ramlan, K Hew, AH Engman, A Pillai, ... Nature communications 13 (1), 1-22, 2022 | 6 | 2022 |
Peptides and Compounds that Bind to Elongation Initiation Factor 4E S Ng, CJ Brown US Patent App. 17/436,118, 2022 | | 2022 |
Molecular descriptors suggest stapling as a strategy for optimizing membrane permeability of cyclic peptides J Li, S KANNAN, P ARONICA, C BROWN, A Partridge, C Verma The Journal of Chemical Physics, 2022 | | 2022 |
Development of a Novel Peptide Aptamer that Interacts with the eIF4E Capped-mRNA Binding Site using Peptide Epitope Linker Evolution (PELE) Y Frosi, S Ng, YC Lin, S Jiang, R Ramlan, D Lama, C Verma, I Asial, ... RSC Chemical Biology, 2022 | 1 | 2022 |
Correction to: Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides TJ Desai, B Habulihaz, JR Cannon, A Chandramohan, HYK Kaan, ... Pharmaceutical research 38 (4), 735-736, 2021 | | 2021 |
Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides (Mar, 10.1007/s11095-021-03005-z, 2021) TJ Desai, B Habulihaz, JR Cannon, A Chandramohan, HYK Kaan, ... PHARMACEUTICAL RESEARCH 38 (4), 735-736, 2021 | | 2021 |
Engineering Disulphide-Free Autonomous Antibody VH Domains to modulate intracellular pathways Y Frosi, S Jiang, SR Ramlan, KH Hew, AH Engman, A Pillai, YX Cheng, ... | 1 | 2021 |
Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides TJ Desai, B Habulihaz, JR Cannon, A Chandramohan, HYK Kaan, ... Pharmaceutical research, 1-8, 2021 | 10 | 2021 |
NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability Assay A Peier, L Ge, N Boyer, J Frost, R Duggal, K Biswas, S Edmondson, ... ACS Chemical Biology 16 (2), 293-309, 2021 | 36 | 2021 |
Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling S Lim, N Boyer, N Boo, C Huang, G Venkatachalam, YCA Juang, ... Chemical Science, 2021 | 15 | 2021 |
Conformational ordering of intrinsically disordered peptides for targeting translation initiation CJ Brown, CS Verma, DP Lane, D Lama Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (1), 129775, 2021 | 2 | 2021 |
Directed co-evolution of interacting protein–peptide pairs by compartmentalized two-hybrid replication (C2HR) JW Siau, S Nonis, S Chee, LQ Koh, FJ Ferrer, CJ Brown, FJ Ghadessy Nucleic acids research 48 (22), e128-e128, 2020 | 4 | 2020 |
Enhancing the therapeutic effects of in vitro targeted radionuclide therapy of 3D multicellular tumor spheroids using the novel stapled MDM2/X-p53 antagonist PM2 ACL Mortensen, E Morin, CJ Brown, DP Lane, M Nestor EJNMMI research 10 (1), 1-10, 2020 | 8 | 2020 |
Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells Y Frosi, SR Ramlan, CJ Brown JoVE (Journal of Visualized Experiments), e60850, 2020 | | 2020 |