AAV-mediated gene delivery to the cardiac conduction system T Jonker, AR Boender, M Klerk, P Barnett, AAF De Vries, VM Christoffels, ... Cardiovascular Research 120 (Supplement_1), cvae088. 071, 2024 | | 2024 |
PO-05-203 AAV6-MEDIATED GENE TRANSFER OF HCN1-ΔΔΔ GENERATES MORE POTENT PACING THAN HCN2 YET WITH A POTENTIAL RISK FOR PRO-ARRHYTHMIA AC i Barea, J Wang, T Jonker, E Birza, M Klerk, A Boender, M Jansen, ... Heart Rhythm 21 (5), S586-S587, 2024 | | 2024 |
Role of Genetic Variation in Transcriptional Regulatory Elements in Heart Rhythm T Jonker, P Barnett, GJJ Boink, VM Christoffels Cells 13 (1), 4, 2023 | | 2023 |
TGFBR1 Variants Can Associate with Non-Syndromic Congenital Heart Disease without Aortopathy M Alaamery, N Albesher, F Alhabshan, P Barnett, M Salim Kabbani, ... Journal of cardiovascular development and disease 10 (11), 455, 2023 | | 2023 |
AAV6-mediated gene transfer of HCN1-ddd generates slightly faster baseline beating rates as compared to Hcn2 yet with a potential risk for pro-arrhythmia A Cervera Barea, J Wang, T Jonker, M Klerk, A Boender, M Jansen, ... European Heart Journal 44 (Supplement_2), ehad655. 3134, 2023 | | 2023 |
Unravelling the signaling pathway downstream of the neurokinin receptor in atrium: discovering novel anti-arrhythmic targets for treatment of atrial fibrillation MR Rivaud, S Casini, P Barnett, AO Verkerk, C Schumacher, ... European Heart Journal 44 (Supplement_2), ehad655. 3170, 2023 | | 2023 |
PO-02-244 AAV6-MEDIATED GFP GENE TRANSFER INDUCES TACHYARRHYTHMIAS IN A PORCINE MODEL OF AV BLOCK AC i Barea, J Wang, M Klerk, MM Ramírez, M Jansen, J Visser, ... Heart Rhythm 20 (5), S285, 2023 | | 2023 |
PO-02-242 AAV6-CTNT-HCN2/SKM1 GENE TRANSFER ENABLES A TRANSIENT BIOLOGICAL PACEMAKER ACTIVITY IN A PORCINE MODEL OF CAVB AC i Barea, J Wang, M Klerk, A Boender, M Jansen, J Visser, ... Heart Rhythm 20 (5), S284, 2023 | | 2023 |
Regulatory element usage in healthy and failing human heart tissue VM Christoffels, P Barnett Nature cardiovascular research 2 (1), 10-12, 2023 | | 2023 |
Gene Transfer of SCN10A-short Improves Cardiac Conduction in WT and Scn5a (Het) Mice J Wang, AO Verkerk, M Klerk, AR Boender, HL Tan, H Devalla, ... HUMAN GENE THERAPY 33 (23-24), A204-A205, 2022 | | 2022 |
Neuregulin-1 enhances cell-cycle activity, delays cardiac fibrosis, and improves cardiac performance in rat pups with right ventricular pressure load GPL Bossers, M Günthel, DE van der Feen, QAJ Hagdorn, AMC Koop, ... The Journal of Thoracic and Cardiovascular Surgery 164 (6), e493-e510, 2022 | 6 | 2022 |
BS-514-01 SCN10ASHORT AS A NOVEL GENE THERAPY TARGET TO TREAT CONDUCTION DEFECTS J Wang, AO Verkerk, M Klerk, A Boender, HL Tan, H Devalla, ... Heart Rhythm 19 (5), S30-S31, 2022 | 1 | 2022 |
Patient-specific TBX5-G125R variant induces profound transcriptional deregulation and atrial dysfunction AF van Ouwerkerk, FM Bosada, K van Duijvenboden, AC Houweling, ... Circulation 145 (8), 606-619, 2022 | 21 | 2022 |
Structure and physiological function of vanadium chloroperoxidase R Wever, P Barnett, WEC Hemrika Transition Metals in Microbial Metabolism, 415-433, 2022 | 2 | 2022 |
Common genetic variants contribute to risk of transposition of the great arteries D Škorić-Milosavljević, R Tadros, FM Bosada, F Tessadori, JH Van Weerd, ... Circulation research 130 (2), 166-180, 2022 | 22 | 2022 |
Epigenetic state changes underlie metabolic switch in mouse post-infarction border zone cardiomyocytes M Günthel, K van Duijvenboden, DEM de Bakker, IB Hooijkaas, J Bakkers, ... Journal of cardiovascular development and disease 8 (11), 134, 2021 | 8 | 2021 |
Variant Intronic Enhancer Controls SCN10A-short Expression and Heart Conduction JCK Man, FM Bosada, KT Scholman, JA Offerhaus, R Walsh, ... Circulation 144 (3), 229-242, 2021 | 26 | 2021 |
Neuregulin-1 enhances cell-cycle activity, delays cardiac fibrosis, and improves cardiac performance in rat pups with right ventricular pressure load QAJ Hagdorn, AMC Koop, K van Duijvenboden, P Barnett, MAJ Borgdorff, ... | | 2021 |
T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system RA Mohan, FM Bosada, JH van Weerd, K van Duijvenboden, J Wang, ... Proceedings of the National Academy of Sciences 117 (31), 18617-18626, 2020 | 24 | 2020 |
Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction JH van Weerd, RA Mohan, K van Duijvenboden, IB Hooijkaas, V Wakker, ... Elife 9, e56697, 2020 | 10 | 2020 |