Interaction Networks within Disease-Associated GαS Variants Characterized by an Integrative Biophysical Approach K Anazia, L Koenekoop, G Ferré, E Petracco, H Gutiérrez-de-Teran, ... Journal of Biological Chemistry, 107497, 2024 | | 2024 |
Membrane mimetic-dependence of GPCR energy landscapes N Thakur, AP Ray, B Jin, NP Afsharian, E Lyman, ZG Gao, KA Jacobson, ... Structure 32 (5), 523-535. e5, 2024 | 2 | 2024 |
Protein-peg interactions that redirect the thermal unfolding pathway of pegylated human galectin-3c AP MT Eddy, ME Harris US Patent US20240100174A1, 2024 | | 2024 |
Visualizing the impact of disease-associated mutations on G protein–nucleotide interactions K Anazia, L Koenekoop, G Ferré, E Petracco, H Gutiérrez-de-Teran, ... bioRxiv, 2024.01. 30.578006, 2024 | | 2024 |
Single-molecule visualization of human A2A adenosine receptor activation by a G protein and constitutively activating mutations S Wei, NG Pour, S Tiruvadi-Krishnan, AP Ray, N Thakur, MT Eddy, ... Communications Biology 6 (1), 1218, 2023 | 3 | 2023 |
Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors B Jin, N Thakur, AV Wijesekara, MT Eddy Current Opinion in Pharmacology, 102364, 2023 | 2 | 2023 |
Dual mechanisms of cholesterol-GPCR interactions that depend on membrane phospholipid composition AP Ray, N Thakur, NG Pour, MT Eddy Structure, 2023 | 13 | 2023 |
Conserved Protein–Polymer Interactions across Structurally Diverse Polymers Underlie Alterations to Protein Thermal Unfolding A Pritzlaff, G Ferré, E Dargassies, CO Williams, DD Gonzalez, MT Eddy ACS Central Science, 2023 | 4 | 2023 |
Anionic phospholipids control mechanisms of GPCR-G protein recognition N Thakur, AP Ray, L Sharp, B Jin, A Duong, NG Pour, S Obeng, ... Nature Communications 14 (1), 794, 2023 | 27 | 2023 |
Global insights into the fine tuning of human A2AAR conformational dynamics in a ternary complex with an engineered G protein viewed by NMR G Ferré, K Anazia, LO Silva, N Thakur, AP Ray, MT Eddy Cell Reports 41 (12), 111844, 2022 | 7 | 2022 |
Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence spectroscopy N Thakur, S Wei, AP Ray, R Lamichhane, MT Eddy STAR Protocols 3 (3), 101535, 2022 | 14 | 2022 |
Atomic‐Scale View of Protein–PEG Interactions that Redirect the Thermal Unfolding Pathway of PEGylated Human Galectin‐3 A Pritzlaff, G Ferré, E Mulry, L Lin, NG Pour, M Eddy, DA Savin, M Harris Angewandte Chemie International Edition, 2022 | 5 | 2022 |
A Comparative Study of Interfacial Environments in Lipid Nanodiscs and Vesicles X You, N Thakur, AP Ray, MT Eddy, CR Baiz Biophysical Reports, 100066, 2022 | 1 | 2022 |
Slow conformational dynamics of the human A2A adenosine receptor are temporally ordered S Wei, N Thakur, AP Ray, B Jin, S Obeng, CR McCurdy, LR McMahon, ... Structure, 2021 | 19 | 2021 |
Production of a Human Histamine Receptor for NMR Spectroscopy in Aqueous Solutions EK Mulry, AP Ray, MT Eddy Biomolecules 11 (5), 632, 2021 | 5 | 2021 |
NMR Spectroscopic Studies of Ion Channels in Lipid Bilayers: Sample Preparation Strategies Exemplified by the Voltage Dependent Anion Channel. R Silvers, MT Eddy Methods in Molecular Biology (Clifton, NJ) 2302, 201-217, 2021 | 4 | 2021 |
A2A Adenosine Receptor Partial Agonism Related to Structural Rearrangements in an Activation Microswitch MT Eddy, BT Martin, K Wüthrich Structure, 2020 | 31 | 2020 |
Structural Biology of Human GPCR Drugs and Endogenous Ligands-Insights from NMR Spectroscopy G Ferré, M Eddy Methods, 2020 | 6 | 2020 |
Adenosine A 2A receptor antagonists: From caffeine to selective non-xanthines KA Jacobson, ZG Gao, P Matricon, MT Eddy, J Carlsson British journal of pharmacology, 2020 | 70 | 2020 |
Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR MT Eddy, TY Yu, G Wagner, RG Griffin Journal of Biomolecular NMR, 1-10, 2019 | 17 | 2019 |