关注
Matthew Eddy
标题
引用次数
年份
Interaction Networks within Disease-Associated GαS Variants Characterized by an Integrative Biophysical Approach
K Anazia, L Koenekoop, G Ferré, E Petracco, H Gutiérrez-de-Teran, ...
Journal of Biological Chemistry, 107497, 2024
2024
Membrane mimetic-dependence of GPCR energy landscapes
N Thakur, AP Ray, B Jin, NP Afsharian, E Lyman, ZG Gao, KA Jacobson, ...
Structure 32 (5), 523-535. e5, 2024
22024
Protein-peg interactions that redirect the thermal unfolding pathway of pegylated human galectin-3c
AP MT Eddy, ME Harris
US Patent US20240100174A1, 2024
2024
Visualizing the impact of disease-associated mutations on G protein–nucleotide interactions
K Anazia, L Koenekoop, G Ferré, E Petracco, H Gutiérrez-de-Teran, ...
bioRxiv, 2024.01. 30.578006, 2024
2024
Single-molecule visualization of human A2A adenosine receptor activation by a G protein and constitutively activating mutations
S Wei, NG Pour, S Tiruvadi-Krishnan, AP Ray, N Thakur, MT Eddy, ...
Communications Biology 6 (1), 1218, 2023
32023
Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors
B Jin, N Thakur, AV Wijesekara, MT Eddy
Current Opinion in Pharmacology, 102364, 2023
22023
Dual mechanisms of cholesterol-GPCR interactions that depend on membrane phospholipid composition
AP Ray, N Thakur, NG Pour, MT Eddy
Structure, 2023
132023
Conserved Protein–Polymer Interactions across Structurally Diverse Polymers Underlie Alterations to Protein Thermal Unfolding
A Pritzlaff, G Ferré, E Dargassies, CO Williams, DD Gonzalez, MT Eddy
ACS Central Science, 2023
42023
Anionic phospholipids control mechanisms of GPCR-G protein recognition
N Thakur, AP Ray, L Sharp, B Jin, A Duong, NG Pour, S Obeng, ...
Nature Communications 14 (1), 794, 2023
272023
Global insights into the fine tuning of human A2AAR conformational dynamics in a ternary complex with an engineered G protein viewed by NMR
G Ferré, K Anazia, LO Silva, N Thakur, AP Ray, MT Eddy
Cell Reports 41 (12), 111844, 2022
72022
Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence spectroscopy
N Thakur, S Wei, AP Ray, R Lamichhane, MT Eddy
STAR Protocols 3 (3), 101535, 2022
142022
Atomic‐Scale View of Protein–PEG Interactions that Redirect the Thermal Unfolding Pathway of PEGylated Human Galectin‐3
A Pritzlaff, G Ferré, E Mulry, L Lin, NG Pour, M Eddy, DA Savin, M Harris
Angewandte Chemie International Edition, 2022
52022
A Comparative Study of Interfacial Environments in Lipid Nanodiscs and Vesicles
X You, N Thakur, AP Ray, MT Eddy, CR Baiz
Biophysical Reports, 100066, 2022
12022
Slow conformational dynamics of the human A2A adenosine receptor are temporally ordered
S Wei, N Thakur, AP Ray, B Jin, S Obeng, CR McCurdy, LR McMahon, ...
Structure, 2021
192021
Production of a Human Histamine Receptor for NMR Spectroscopy in Aqueous Solutions
EK Mulry, AP Ray, MT Eddy
Biomolecules 11 (5), 632, 2021
52021
NMR Spectroscopic Studies of Ion Channels in Lipid Bilayers: Sample Preparation Strategies Exemplified by the Voltage Dependent Anion Channel.
R Silvers, MT Eddy
Methods in Molecular Biology (Clifton, NJ) 2302, 201-217, 2021
42021
A2A Adenosine Receptor Partial Agonism Related to Structural Rearrangements in an Activation Microswitch
MT Eddy, BT Martin, K Wüthrich
Structure, 2020
312020
Structural Biology of Human GPCR Drugs and Endogenous Ligands-Insights from NMR Spectroscopy
G Ferré, M Eddy
Methods, 2020
62020
Adenosine A 2A receptor antagonists: From caffeine to selective non-xanthines
KA Jacobson, ZG Gao, P Matricon, MT Eddy, J Carlsson
British journal of pharmacology, 2020
702020
Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR
MT Eddy, TY Yu, G Wagner, RG Griffin
Journal of Biomolecular NMR, 1-10, 2019
172019
系统目前无法执行此操作,请稍后再试。
文章 1–20