Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in CD46 and other loci F Grodstein, B Lemos, J Yang, K de Paiva Lopes, RA Vialle, N Seyfried, ... Epigenetics 19 (1), 2392050, 2024 | | 2024 |
Blood‐based multivariate methylation risk score for cognitive impairment and dementia J Koetsier, R Cavill, R Reijnders, J Harvey, J Homann, M Kouhsar, ... Alzheimer's & Dementia, 2024 | 1 | 2024 |
Long-read transcript sequencing identifies differential isoform expression in the entorhinal cortex in a transgenic model of tau pathology SK Leung, RA Bamford, AR Jeffries, I Castanho, B Chioza, CS Flaxman, ... Nature Communications 15 (1), 6458, 2024 | 2 | 2024 |
Whole blood DNA methylation changes are associated with anti-TNF drug concentration in patients with Crohn’s disease S Lin, E Hannon, M Reppell, JF Waring, N Smaoui, V Pivorunas, H Guay, ... Journal of Crohn's and Colitis 18 (8), 1190-1201, 2024 | 8 | 2024 |
Developmentally dynamic changes in DNA methylation in the human pancreas A MacCalman, E De Franco, A Franklin, CS Flaxman, SJ Richardson, ... BMC genomics 25 (1), 553, 2024 | 1 | 2024 |
Accelerated pace of aging in schizophrenia: five case-control studies A Caspi, G Shireby, J Mill, TE Moffitt, K Sugden, E Hannon Biological Psychiatry 95 (11), 1038-1047, 2024 | 8 | 2024 |
Brain cell-type shifts in Alzheimer’s disease, autism, and schizophrenia interrogated using methylomics and genetics CX Yap, DD Vo, MG Heffel, A Bhattacharya, C Wen, Y Yang, KE Kemper, ... Science Advances 10 (21), eadn7655, 2024 | 2 | 2024 |
Meta-analysis of epigenetic aging in schizophrenia reveals multifaceted relationships with age, sex, illness duration, and polygenic risk APS Ori, LM Olde Loohuis, J Guintivano, E Hannon, E Dempster, ... Clinical Epigenetics 16 (1), 53, 2024 | 2 | 2024 |
Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles E Hannon, EL Dempster, JP Davies, B Chioza, GET Blake, J Burrage, ... BMC biology 22 (1), 17, 2024 | 2 | 2024 |
Imputed DNA methylation outperforms measured loci associations with smoking and chronological age A Richmond, J Mur, S Harris, J Corley, HR Elliott, CN Foley, E Hannon, ... bioRxiv, 2024.09. 05.611501, 2024 | | 2024 |
Leveraging epigenetic signatures to determine the cell-type of origin from long read sequencing data E Hannon, J Mill bioRxiv, 2024.06. 03.597114, 2024 | | 2024 |
An atlas of expressed transcripts in the prenatal and postnatal human cortex R Bamford, SK Leung, VK Chundru, AR Jeffries, J Davies, A Franklin, ... bioRxiv, 2024.05. 24.595768, 2024 | | 2024 |
Uncertainty quantification of reference-based cellular deconvolution algorithms DS Vellame, G Shireby, A MacCalman, EL Dempster, J Burrage, ... Epigenetics 18 (1), 2137659, 2023 | 8 | 2023 |
Isoform characterisation & splicing signatures of AD‐risk genes using long‐read sequencing SK Leung, I Castanho, A Jeffries, K Moore, E Dempster, JT Brown, ... Alzheimer's & Dementia 19, e074237, 2023 | | 2023 |
T86. PREDICTING PSYCHOSIS: EXPLORING THE ADDITIVE AND INTERACTION EFFECTS OF GENETIC AND EPIGENETIC RISK SCORES L Spindola, AK Stavrum, K O'Connell, E Hannon, J Mill, S Djurovic, I Melle, ... European Neuropsychopharmacology 75, S208, 2023 | | 2023 |
W76. CELL-SPECIFIC METHYLOMIC VARIATION IN NEURODEVELOPMENT AND SCHIZOPHRENIA J Mill, E Hannon, E Dempster, A Franklin, J Burrage, J Davies, B Chioza, ... European Neuropsychopharmacology 75, S144-S145, 2023 | | 2023 |
59. ULTRA-DEEP LONG READ TRANSCRIPTOME SEQUENCING REVEALS DRAMATIC ISOFORM DIVERSITY ACROSS HUMAN CORTEX DEVELOPMENT: RELEVANCE FOR GENETIC STUDIES OF PSYCHIATRIC DISORDERS RA Bamford, SK Leung, AR Jeffries, A Franklin, G Commin, J Davies, ... European Neuropsychopharmacology 75, S88, 2023 | | 2023 |
Methylomic signature of current cannabis use in two first-episode psychosis cohorts E Dempster, C Wong, J Burrage, E Hannon, D Quattrone, T Giulia, ... | | 2023 |
Cross-national and cross-generational evidence that educational attainment may slow the pace of aging in European-descent individuals K Sugden, TE Moffitt, TE Arpawong, L Arseneault, DW Belsky, ... The Journals of Gerontology: Series B 78 (8), 1375-1385, 2023 | 15 | 2023 |
Genetic impacts on DNA methylation help elucidate regulatory genomic processes S Villicaña, J Castillo-Fernandez, E Hannon, C Christiansen, PC Tsai, ... Genome Biology 24 (1), 176, 2023 | 13 | 2023 |