| IDENTIFICATION AND VALIDATION OF POTENTIAL BIOMARKERS FOR DECITABINE-MEDIATED SENSITIZATION TO TEMOZOLOMIDE IN GLIOBLASTOMA TS Hurtado, J Inocencio, A Mead, G Fang, B Pai, N Tsankova, R Yong NEURO-ONCOLOGY 25, 2023 | | 2023 |
| The identification of GPR52 agonist HTL0041178, a potential therapy for schizophrenia and related psychiatric disorders S Poulter, N Austin, R Armstrong, M Barnes, SJ Bucknell, A Higueruelo, ... ACS Medicinal Chemistry Letters 14 (4), 499-505, 2023 | 5 | 2023 |
| Translation of in vitro cannabinoid 1 receptor agonist activity to in vivo pharmacodynamic endpoints S Jenkinson, SMG Goody, A Bassyouni, R Jones, A Otto-Bruc, ... Journal of Pharmacological and Toxicological Methods 104, 106899, 2020 | 1 | 2020 |
| Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF … SA Nickolls, R Gurrell, G van Amerongen, J Kammonen, L Cao, AR Brown, ... British journal of pharmacology 175 (4), 708-725, 2018 | 53 | 2018 |
| Dopamine D3/D2 receptor antagonist PF-4363467 attenuates opioid drug-seeking behavior without concomitant D2 side effects TT Wager, T Chappie, D Horton, RY Chandrasekaran, B Samas, ... ACS chemical neuroscience 8 (1), 165-177, 2017 | 21 | 2017 |
| Drug Addiction AN Mead, P Vezina Elsevier, 2017 | 3 | 2017 |
| Assessing the predictive value of the rodent neurofunctional assessment for commonly reported adverse events in phase I clinical trials AN Mead, HR Amouzadeh, K Chapman, L Ewart, A Giarola, SJ Jackson, ... Regulatory Toxicology and Pharmacology 80, 348-357, 2016 | 59 | 2016 |
| THE PREDICTIVE VALUE OF THE RODENT NEUROFUNCTIONAL ASSESSMENT FOR CENTRAL NERVOUS SYSTEM EVENTS IN PHASE I CLINICAL TRIALS AN Mead, HR Amouzadeh, K Chapman, L Ewart, A Giarola, S Jackson, ... Toxicological Sciences, 2016 | | 2016 |
| Casein kinase-1 inhibitors as a novel treatment for substance use disorders DB Horton, E Dunn-Sims, TT Wager, C Chang, A Doran, A Rosado, ... Drug and Alcohol Dependence 100 (156), e98, 2015 | | 2015 |
| Casein kinase 1δ/ε inhibitor PF-5006739 attenuates opioid drug-seeking behavior TT Wager, RY Chandrasekaran, J Bradley, D Rubitski, H Berke, S Mente, ... ACS Chemical Neuroscience 5 (12), 1253-1265, 2014 | 38 | 2014 |
| The concordance between nonclinical and phase I clinical cardiovascular assessment from a cross-company data sharing initiative L Ewart, M Aylott, M Deurinck, M Engwall, DJ Gallacher, H Geys, P Jarvis, ... Toxicological Sciences 142 (2), 427-435, 2014 | 75 | 2014 |
| Appropriate experimental approaches for predicting abuse potential and addictive qualities in preclinical drug discovery AN Mead Expert Opinion on Drug Discovery 9 (11), 1281-1291, 2014 | 13 | 2014 |
| A translational pharmacology approach to understanding the predictive value of abuse potential assessments DB Horton, DM Potter, AN Mead Behavioural pharmacology 24 (5 and 6), 410-436, 2013 | 51 | 2013 |
| Analysis of concordance of nonclinical rodent respiratory function measurements to phase i trial outcome using the animal model framework L Ewart, H Amouzadeh, M Aylott, K Chapman, P Jordaan, D Leishman, ... Journal of Pharmacological and Toxicological Methods 1 (68), e42-e43, 2013 | 1 | 2013 |
| Self administration of “weak” reinforcers in the rat N Nawreen, C Tyszkiewicz, D Roberts, D Parker, A Mead Journal of Pharmacological and Toxicological Methods 1 (68), e8, 2013 | | 2013 |
| Use of the beam walking and drug discrimination models for determining intrinsic efficacy and selectivity of subtype selective GABA-A ligands in rodents C Hsu, R Newman, S Shires, K Tse, A Warr, A Mead, G Waldron Journal of Pharmacological and Toxicological Methods 1 (68), e8, 2013 | | 2013 |
| Establishing the EEG Sleep Profile of Cocaine Withdrawal in Sprague–Dawley rats A Rosado, A Mead, J DaSilva Journal of Pharmacological and Toxicological Methods 1 (68), e8, 2013 | | 2013 |
| Drug-induced anxiety and the elevated plus maze: Effect of lighting conditions CM Tyszkiewicz, A Mead Journal of Pharmacological and Toxicological Methods 1 (64), e24, 2011 | | 2011 |
| Short-term social isolation: A possible rodent model for a depressive-like state? CM Tyszkiewicz, KE Cannon, A Mead Journal of Pharmacological and Toxicological Methods 1 (64), e21, 2011 | | 2011 |
| Optimizing learned helplessness testing conditions to detect changes in behavioral despair CM Tyszkiewicz, KE Cannon, A Mead Journal of Pharmacological and Toxicological Methods 1 (64), e21-e22, 2011 | | 2011 |
