| Non-clinical evaluation of NT-112, an autologous T cell product engineered to express an HLA-C* 08: 02-restricted TCR targeting KRAS G12D and resistant to TGF-b inhibition. J Ma, V Tubb, M Mojadidi, K Meade, X Kong, P Kroon, A Sareen, ... Journal of Clinical Oncology 42 (16_suppl), e14533-e14533, 2024 | | 2024 |
| Non-clinical evaluation of NT-175, an autologous T cell product engineered to express an HLA-A* 02: 01-restricted TCR targeting TP53 R175H and resistant to TGF-b inhibition. V Tubb, J Ma, K Buchner, S Eshuis, M Mojadidi, X Kong, P Kroon, ... Journal of Clinical Oncology 42 (16_suppl), 2560-2560, 2024 | | 2024 |
| An open-label, phase 1, multicenter study to evaluate the safety and preliminary anti-tumor activity of NT-112 in human leukocyte antigen-C* 08: 02–positive adult patients with … SR Punekar, M Pelster, CR Becerra, JR Hecht, AS Paulson, P Grierson, ... Journal of Clinical Oncology 42 (16_suppl), TPS2677-TPS2677, 2024 | | 2024 |
| Engineered t cells with reduced tgf-beta receptor signaling JWJ VAN HEIJST, GM Bendle US Patent App. 18/055,370, 2023 | | 2023 |
| METHOD FOR ISOLATION OF TCR GENES ANM Schumacher, C LINNEMANN, T KUILMAN, GM BENDLE, ... | | 2023 |
| DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age J Urbanus, J Cosgrove, JB Beltman, Y Elhanati, RA Moral, C Conrad, ... Nature Communications 14 (1), 2184, 2023 | 5 | 2023 |
| 239 Engineering of potency-enhanced TCR-edited T cells for shared neoantigen-targeted cancer immunotherapy L Kok, S Eshuis, P Kroon, V Tubb, X Kong, C Linnemann, G Bendle, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
| Engineered antigen presenting cells ANM Schumacher, C Linnermann, T Kuilman, GM Bendle, JFC Gadiot, ... US Patent App. 17/578,955, 2022 | | 2022 |
| Peptide markers to track genetically engineered cells C Linnemann, T Kuilman, GM Bendle, JWJ Van Heijst, X Kong, ... US Patent App. 17/557,514, 2022 | | 2022 |
| Association of myeloid liver kinase B1 depletion with a reduction in alveolar macrophage numbers and an impaired host defense during gram-negative pneumonia NA Otto, AF de Vos, JWJ van Heijst, JJTH Roelofs, T van der Poll The Journal of infectious diseases 225 (7), 1284-1295, 2022 | 13 | 2022 |
| An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes LEH van der Donk, J van der Spek, T van Duivenvoorde, MS Ten Brink, ... Biology open 11 (2), bio059032, 2022 | 1 | 2022 |
| Methods to enrich genetically engineered t cells C Linnemann, T Kuilman, GM Bendle, JWJ Van Heijst, X Kong US Patent App. 17/395,132, 2022 | | 2022 |
| Separate signaling events control TCR downregulation and T cell activation in primary human T cells LEH van der Donk, LS Ates, J van der Spek, LM Tukker, TBH Geijtenbeek, ... Immunity, Inflammation and Disease 9 (1), 223-238, 2021 | 15 | 2021 |
| Adherence affects monocyte innate immune function and metabolic reprogramming after lipopolysaccharide stimulation in vitro NA Otto, JM Butler, I Ramirez-Moral, M van Weeghel, JWJ van Heijst, ... The Journal of Immunology 206 (4), 827-838, 2021 | 19 | 2021 |
| Method to isolate tcr genes ANM Schumacher, C Linnemann, T Kuilman, GM Bendle, JFC Gadiot, ... US Patent App. 16/927,661, 2021 | 2 | 2021 |
| Method to isolate tcr genes ANM Schumacher, C LINNEMANN, T KUILMAN, GM Bendle, JFC Gadiot, ... | | 2021 |
| Hypoxia‐Inducible Factor‐1α in Macrophages, but Not in Neutrophils, Is Important for Host Defense during Klebsiella pneumoniae‐Induced Pneumosepsis NA Otto, L Pereverzeva, V Leopold, I Ramirez-Moral, JJTH Roelofs, ... Mediators of Inflammation 2021 (1), 9958281, 2021 | 8 | 2021 |
| Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite-induced murine asthma model J Yang, C van’t Veer, JJTH Roelofs, JWJ van Heijst, AF de Vos, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 316 (1 …, 2019 | 6 | 2019 |
| Unexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and Immunogenicity LS Ates, A Dippenaar, F Sayes, A Pawlik, C Bouchier, L Ma, RM Warren, ... Genome biology and evolution 10 (8), 1858-1874, 2018 | 39 | 2018 |
| RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection LS Ates, F Sayes, W Frigui, R Ummels, MPM Damen, D Bottai, MA Behr, ... PLoS pathogens 14 (6), e1007139, 2018 | 40 | 2018 |
Ton N.M. SchumacherThe Netherlands Cancer Institute, Third Rock Ventures在 nki.nl 的电子邮件经过验证
