RCC1 regulation of subcellular protein localization via Ran GTPase drives pancreatic ductal adenocarcinoma growth SF Bannoura, A Aboukameel, HY Khan, MH Uddin, H Jang, E Beal, ... Cancer Letters, 217275, 2024 | | 2024 |
The Janus kinase 1 is critical for pancreatic cancer initiation and progression H Shrestha, PD Rädler, R Dennaoui, MN Wicker, N Rajbhandari, Y Sun, ... Cell Reports 43 (5), 2024 | 1 | 2024 |
Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure M Saleem, LA Aden, AP Mutchler, C Basu, LA Ertuglu, Q Sheng, ... Circulation Research, 2024 | | 2024 |
Cellular Plasticity in Mammary Gland Development and Breast Cancer MN Wicker, KU Wagner Cancers 15 (23), 5605, 2023 | 2 | 2023 |
Dendritic cell-specific SMAD3, downstream of JAK2, contributes to inflammation and salt-sensitivity of blood pressure M Saleem, L Aden, A Mutchler, C Basu, L Ertuglu, Q Sheng, J Park, ... | | 2023 |
Identification of actionable targets for breast cancer intervention using a diversity outbred mouse model JB Jacob, KC Wei, G Bepler, JD Reyes, A Cani, L Polin, K White, S Kim, ... Iscience 26 (4), 106320, 2023 | 4 | 2023 |
Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis SF Bannoura, A Aboukameel, HY Khan, MH Uddin, E Beal, KU Wagner, ... bioRxiv, 2023.12. 18.572102, 2023 | 1 | 2023 |
Ecdysoneless overexpression drives mammary tumorigenesis through upregulation of c-MYC and glucose metabolism BC Mohapatra, S Mirza, A Bele, CB Gurumurthy, M Raza, I Saleem, ... Molecular Cancer Research 20 (9), 1391-1404, 2022 | 1 | 2022 |
Peripubertal requirement of Tsg101 in maintaining the integrity of membranous structures in mouse oocytes H Shin, D Park, J Kim, MY Nam, S Kwon, DE Um, JE Oh, E Youn, ... Cell Proliferation, e13288, 2022 | 1 | 2022 |
Know thy cells: commonly used triple-negative human breast cancer cell lines carry mutations in RAS and effectors KU Wagner Breast Cancer Research 24 (1), 44, 2022 | 15 | 2022 |
Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux I Dotan, J Yang, J Ikeda, Z Roth, E Pollock-Tahiri, H Desai, ... Communications Biology 5 (1), 132, 2022 | 15 | 2022 |
Tumor susceptibility gene 101 is required for the maintenance of uterine epithelial cells during embryo implantation H Byun, S Kwon, KU Wagner, H Shin, HJ Lim Reproductive Biology and Endocrinology 19, 1-17, 2021 | 2 | 2021 |
Dual recombinase action in the normal and neoplastic mammary gland epithelium PD Rädler, K Vistisen, AA Triplett, R Dennaoui, Y Li, H Shrestha, ... Scientific Reports 11 (1), 20775, 2021 | 3 | 2021 |
PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to EverolimusKPT-9274 Sensitizes PNETs to the mTOR Inhibitor Everolimus GB Mpilla, M Uddin, MN Al-Hallak, A Aboukameel, Y Li, SH Kim, ... Molecular Cancer Therapeutics 20 (10), 1836-1845, 2021 | 22 | 2021 |
Targeting Gi/o protein–coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy C Lyu, Y Ye, MM Lensing, KU Wagner, RJ Weigel, S Chen JCI insight 6 (18), 2021 | 10 | 2021 |
NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers Y Sun, N Yang, FE Utama, SS Udhane, J Zhang, AR Peck, A Yanac, ... Science Advances 7 (38), eabc8145, 2021 | 14 | 2021 |
Models of pancreatic ductal adenocarcinoma R Dennaoui, H Shrestha, KU Wagner Cancer and Metastasis Reviews 40 (3), 803-818, 2021 | 11 | 2021 |
Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells PD Rädler, BL Wehde, AA Triplett, H Shrestha, JH Shepherd, AD Pfefferle, ... Nature Communications 12 (1), 3742, 2021 | 43 | 2021 |
Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity. S Lim, KW Min, JW Park, Y Kim, T Ha, KH Moon, KU Wagner, JW Kim Molecules and Cells 44 (3), 168-178, 2021 | 5 | 2021 |
Exosomal microRNA in Pancreatic Cancer Diagnosis, Prognosis, and Treatment: From Bench to Bedside M Uddin, MN Al-Hallak, PA Philip, RM Mohammad, N Viola, KU Wagner, ... Cancers 13 (11), 2777, 2021 | 33 | 2021 |