| Effect of ferroptosis inhibitors in a murine model of acetaminophen‐induced liver injury OB Adelusi, Y Etemadi, JY Akakpo, A Ramachandran, H Jaeschke Journal of Biochemical and Molecular Toxicology 38 (8), e23791, 2024 | | 2024 |
| Central mechanisms of acetaminophen hepatotoxicity: Mitochondrial dysfunction by protein adducts and oxidant stress H Jaeschke, A Ramachandran Drug Metabolism and Disposition 52 (8), 712-721, 2024 | 7 | 2024 |
| FRI-333 Sibiriline, an inhibitor of regulated necrosis, protects mice against Acetaminophen-induced liver injury, alone or in combination with N-acetyl-cysteine MS Eugenio, G Imerzoukene, A Hamon, C Piquet-Pellorce, A Rapin, ... Journal of Hepatology 80, S109-S110, 2024 | | 2024 |
| The thrombopoietin mimetic JNJ-26366821 reduces the late injury and accelerates the onset of liver recovery after acetaminophen-induced liver injury in mice OB Adelusi, JY Akakpo, G Eichenbaum, E Sadaff, A Ramachandran, ... Archives of Toxicology 98 (6), 1843-1858, 2024 | | 2024 |
| The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failure DS Umbaugh, NT Nguyen, SC Curry, JA Rule, WM Lee, A Ramachandran, ... Hepatology 79 (6), 1352-1364, 2024 | 3 | 2024 |
| The p21+ perinecrotic hepatocytes produce the chemokine CXCL14 after a severe acetaminophen overdose promoting hepatocyte injury and delaying regeneration DS Umbaugh, NT Nguyen, SH Smith, A Ramachandran, H Jaeschke Toxicology 504, 153804, 2024 | 1 | 2024 |
| Comments on: Unveiling the therapeutic promise of natural products in alleviating drug‐induced liver injury: Present advancements and future prospects H Jaeschke, A Ramachandran Phytotherapy Research 38 (4), 1781-1782, 2024 | | 2024 |
| Spatial analysis of renal acetaminophen metabolism and its modulation by 4-methylpyrazole with DESI mass spectrometry imaging JY Akakpo, H Olivos, B Shrestha, A Midey, H Jaeschke, A Ramachandran Toxicological Sciences 198 (2), 328-346, 2024 | 1 | 2024 |
| Hepatocyte miR-21-5p-deficiency alleviates APAP-induced liver injury by inducing PPARγ and autophagy C Xu, F Yan, Y Zhao, H Jaeschke, J Wu, L Fang, L Zhao, Y Zhao, L Wang Toxicological Sciences 198 (1), 50-60, 2024 | 1 | 2024 |
| Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure A Ramachandran, JY Akakpo, SC Curry, BH Rumack, H Jaeschke Biochemical Pharmacology, 116056, 2024 | 1 | 2024 |
| Biomarker discovery in acetaminophen hepatotoxicity: leveraging single-cell transcriptomics and mechanistic insight DS Umbaugh, H Jaeschke Expert Review of Clinical Pharmacology 17 (2), 143-155, 2024 | 2 | 2024 |
| Acetaminophen hepatotoxicity: paradigm for understanding mechanisms of drug-induced liver injury H Jaeschke, A Ramachandran Annual Review of Pathology: Mechanisms of Disease 19 (1), 453-478, 2024 | 16 | 2024 |
| High-Dose Acetaminophen with Concurrent CYP2E1 Inhibition Has Profound Anticancer Activity without Liver Toxicity A Bryan, P Pingali, A Faber, J Landry, JY Akakpo, H Jaeschke, H Li, ... Journal of Pharmacology and Experimental Therapeutics 388 (1), 209-217, 2024 | 2 | 2024 |
| High-throughput screening of novel TFEB agonists in protecting against acetaminophen-induced liver injury in mice X Chao, M Niu, S Wang, X Ma, X Yang, H Sun, X Hu, H Wang, L Zhang, ... Acta Pharmaceutica Sinica B 14 (1), 190-206, 2024 | 1 | 2024 |
| Hepatocyte-specific deletion of small heterodimer partner protects mice against acetaminophen-induced hepatotoxicity via activation of Nrf2 P Ghosh, N Magee, JY Akakpo, F Ahamed, N Eppler, E Jones, Y Yu, L He, ... Toxicological Sciences 197 (1), 53-68, 2024 | | 2024 |
| Translocation of Adenosine A2B Receptor to Mitochondria Influences Cytochrome P450 2E1 Activity after Acetaminophen Overdose G Sanchez-Guerrero, DS Umbaugh, AA Ramachandran, A Artigues, ... Livers 4 (1), 15-30, 2023 | | 2023 |
| Lack of mitochondrial Cyp2E1 drives acetaminophen-induced ER stress-mediated apoptosis in mouse and human kidneys: Inhibition by 4-methylpyrazole but not N-acetylcysteine JY Akakpo, A Ramachandran, BH Rumack, DP Wallace, H Jaeschke Toxicology 500, 153692, 2023 | 4 | 2023 |
| Nrf2 as a therapeutic target in acetaminophen hepatotoxicity: A case study with sulforaphane Y Etemadi, JY Akakpo, A Ramachandran, H Jaeschke Journal of Biochemical and Molecular Toxicology 37 (12), e23505, 2023 | 7 | 2023 |
| The mitochondrial calcium uniporter mediates mitochondrial Fe2+ uptake and hepatotoxicity after acetaminophen J Hu, AL Nieminen, JL Weemhoff, H Jaeschke, LG Murphy, JA Dent, ... Toxicology and Applied Pharmacology 479, 116722, 2023 | 1 | 2023 |
| ACTIVATION OF TFEB PROTECTS AGAINST ACETAMINOPHEN-INDUCED LIVER INJURY IN MICE M Niu, X Chao, S Wang, H Jaeschke, HM Ni, WX Ding HEPATOLOGY 78, S29-S29, 2023 | | 2023 |
Anup RamachandranUniversity of Kansas Medical Center在 kumc.edu 的电子邮件经过验证
